Browsing by Author "Ragbetli, MÇ"

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Numerical Density of Pyramidal Neurons in the Hippocampus of 4 and 20 Week Old Male and Female Rats
(John Wiley & Sons inc, 2003) Kaplan, S; Ragbetli, MÇ; Canan, S; Sahin, B; Marangoz, C
A study designed to investigate how the cellular laterality in rostro-caudal direction changes due to age and sex was presented. It is a well-known fact that asymmetry is an important issue in understanding brain functions. Frontal sections of 5 Pin thickness with 200 mum intervals were taken from both dorsal hippocampi of 4- and 20-week-old male and female rats. Sections were stained with hematoxylin-eosin and the levels of sections were determined according to a stereotaxic atlas. In each level, numerical density of pyramidal cells of the right and left area CA1, CA3 and CA4 of dorsal hippocampi were estimated by means of counting pyramidal cells under 10 x 40 magnification. Numerical cell density obtained from the right and left dorsal hippocampi of male and female rats were compared. Results are as follows: 1) Numerical cell density in the left and right dorsal hippocampi of 20-week female rats was not high than 4-week female dorsal hippocampi (p>0.05). 2) Difference between 4-week-old female and male dorsal hippocampi of right and left CA1, CA3 and CA4 areas were not raised a significant level (p> 0.05). Differences between 20-week-old group of male and female rats with the exception of female CA4 area were not also significant. 3) Right and left dorsal hippocampi CA4 areas of the 20-week-old group showed a higher numerical density than the same area of the 4-week-old group (p<0.007). This difference may show a postnatal neurogenesis in area CA4. The results, which are summarized above, may be helpful in understanding the mechanisms of human brains.
The Relationship of Callosal Anatomy To Paw Preference in Dogs
(Swets Zeitlinger Publishers, 2000) Aydinlioglu, A; Arslan, K; Erdogan, AR; Ragbetli, MÇ; Keles, P; Diyarbakirli, S
Previous studies have described the paw preference and asymmetry in dog brains, based on experimental studies. The purpose of the present study is to investigate a possible association between callosal anatomy and paw preference in dogs. The midsagittal area of the dog corpus callosum was measured in its entirety and in six subdivisions in a sample of 21 brains obtained from 9 male and 12 female mongrel dogs which had paw preference testing. The present study showed significant paw differences in dog corpus callosum. A posterior segment of the callosum, the isthmus, was significantly larger in the right pawedness than the left.
Sex Differences and Right-Left Asymmetries in Rat Hippocampal Components
(Taylor & Francis Ltd, 2002) Ragbetli, MÇ; Aydinlioglu, A; Kaplan, S
Previous reports have indicated morphologic hippocampal asymmetry in thickness in male and female rats. In the present study, the possible sex differences and right-left asymmetries in rat hippocampal components were investigated. Pyramidal cells in four hippocampal sectors on thionin-stained sections were counted and the thickness of the hippocampal components was measured on microslide-projected images. The present study showed significant sexual dimorphism in two hippocampi as well as asymmetry in male. These findings agree with those found in humans.
Sex Differences in Dog Corpus Callosum
(Swets Zeitlinger Publishers, 2000) Aydinlioglu, A; Arslan, K; Ragbetli, MÇ; Erdogan, AR; Keles, P; Diyarbakirli, S
Human studies reported sex differences in size and shape of the corpus callosum. These observations have been contested. The purpose of the present study is to investigate possible sex differences in the corpus callosum of dogs. The entire brains including the medulla from 12 female and 9 male adult mongrel dogs wore removed and weighed. Total and partial area measurements of the callosum were made from photographic tracings of its outline. The callosum was partitioned into 3 regions; anterior half, posterior half, posterior one-fifth. The total corpus callosum, anterior half, posterior half, and posterior fifth or splenium areas were measured. Sex differences were found. The anterior half, the posterior half, the posterior fifth, and the total callosum were significantly greater in absolute area in males than in females.