Browsing by Author "Sagici, Ozge"
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Conference Object Cognitive Impairment in Multiple Sclerosis: Comparing Dual-Task Performance, Anxiety, Depression and Disability(Sage Publications Ltd, 2023) Sagici, Ozge; Ozdogar, Asiye Tuba; Baba, Cavid; Ozakbas, SerkanConference Object Cognitive Impairment Is Associated With Chronic Neuropathic Pain(Sage Publications Ltd, 2023) Karakas, Hilal; Ozdogar, Asiye Tuba; Sagici, Ozge; Samadzade, Ulvi; Kahraman, Turhan; Ozakbas, SerkanConference Object Comparison of Early-Onset and Very Early-Onset People With Multiple Sclerosis Based on Cognitive and Physical Assessments(Sage Publications Ltd, 2023) Kaya, Ergi; Ozdogar, Asiye Tuba; Karakas, Hilal; Sagici, Ozge; Ozakbas, SerkanConference Object Comparison of Two Commonly Used Depression Questionnaires Based on Reflecting Physical and Cognitive Functions in People With Multiple Sclerosis(Sage Publications Ltd, 2023) Ozdogar, Asiye Tuba; Sagici, Ozge; Aslan, Taha; Ozcelik, Sinem; Ozakbas, SerkanConference Object Correlation Between Lesion Loads and Cognitive, Social Cognitive, and Physical Measures in Persons With Multiple Sclerosis(Sage Publications Ltd, 2023) Aslan, Taha; Ozdogar, Asiye Tuba; Sagici, Ozge; Karakas, Hilal; Ozakbas, SerkanConference Object Do Brand-Name and Generic-Brand Drugs of Dimethyl Fumarate Show Similar Efficacy and Safety Profiles in Relapsing-Remitting Multiple Sclerosis(Sage Publications Ltd, 2023) Kaya, Ergi; Sagici, Ozge; Ozdogar, Asiye Tuba; Ozcelik, Sinem; Ozakbas, SerkanConference Object The Effect of Cognitive Impairment on Six Spot Step Test Performance in People With Multiple Sclerosis(Sage Publications Ltd, 2023) Dastan, Seda; Sagici, Ozge; Ozdogar, Asiye Tuba; Kaya, Ergi; Ozakbas, SerkanConference Object Effect of Telerehabilitation-Based Motor Imagery Training on Pain and Related Factors in People With Multiple Sclerosis: a Randomized, Controlled, Assessor-Blinded Trial(Sage Publications Ltd, 2023) Karakas, Hilal; Kahraman, Turhan; Ozdogar, Asiye Tuba; Sagici, Ozge; Baba, Cavid; Ozakbas, SerkanConference Object The Effect of Two Gram of Methylprednisol Treatment on Physical and Cognitive Status in People With Multiple Sclerosis(Sage Publications Ltd, 2023) Ozakbas, Serkan; Dastan, Seda; Sagici, Ozge; Aslan, Taha; Ozdogar, Asiye TubaConference Object Effects of Two Grams of Methylprednisolone in People With Multiple Sclerosis Who Received One Gram of Methylprednisolone for Relapses(Sage Publications Ltd, 2023) Alizada, Said; Ozcelik, Sinem; Dastan, Seda; Sagici, Ozge; Ozdogar, Asiye Tuba; Ozakbas, SerkanConference Object Efficacy of Original Fingolimod Vs. Generic-Brand Drugs in Treating Multiple Sclerosis: a Comparative Study Using Real-World Data From Turkey(Sage Publications Ltd, 2023) Ozcelik, Sinem; Sagici, Ozge; Ozdogar, Asiye Tuba; Kaya, Ergi; Ozakbas, SerkanConference Object Factors Explained the Objective and Subjective Cognitive Fatigue in People With Multiple Sclerosis(Sage Publications Ltd, 2023) Karakas, Hilal; Ozdogar, Asiye Tuba; Sagici, Ozge; Ozakbas, SerkanArticle Factors Related To Restless Leg Syndrome in Neuromyelitis Optica Spectrum Disorder(Elsevier Sci Ltd, 2025) Ozdogar, Asiye Tuba; Karakas, Hilal; Dastan, Seda; Kaya, Ergi; Sagici, Ozge; Ozcelik, Sinem; Ozakbas, SerkanObjective: Although the feeling of unrest in the legs is frequently reported as a sensory symptom by people with Neuromyelitis Optica Spectrum Disorder (NMOSD, pwNMOSD), there are limited studies to investigate the relationship between Restless Legs Syndrome (RLS) and NMOSD. The study's primary aim is to determine the frequency and severity of RLS in pwNMOSD. The other aim is to compare the sleep quality, daytime sleepiness level, quality of life, fatigue, magnetic resonance imaging results, and cognitive functions in RLS-positive and negative pwNMOSD. Methods: The RLS diagnosis was performed with RLS-Diagnostic Index criteria. The patient-reported outcomes were RLS Severity Rating Score, The Preference-Based Multiple Sclerosis Index (PBMSI), the Modified Fatigue Impact Scale (MFIS), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale (ESS). Cognitive function was assessed with The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) battery. The neurologist recorded the demographic and clinical characteristics of the participants. Results: The RLS was detected in 17 (21.5 %) of the 79 pwNMOSD participants. Fifty-six pwNMOSD were reached to assess cognitive functions and patient-reported outcomes. The rate of RLS was 60.71 % in this group. The PBMSI, PSQI, MFIS, and ESS scores were significantly different in RLS-positive participants than in RLS-negative (p < 0.05). Moreover, while participants' visuospatial and verbal learning was similar, the processing speed was slow in the RLS-positive group (p > 0.05). Conclusions: Our preliminary results have shown that the RLS frequency is high in pwNMOSD. This study suggests a connection between the presence of RLS and worse sleep quality, fatigue level, processing speed, and quality of life in the NMOSD population. However, our results should be considered with the fact that the study has a small sample size and needs future studies to confirm our results for solid evidence.Article Feasibility of Telerehabilitation-Based Pelvic Floor Muscle Training for Urinary Incontinence in People With Multiple Sclerosis: a Randomized, Controlled, Assessor-Blinded Study(Lippincott Williams & Wilkins, 2023) Yavas, Ipek; Kahraman, Turhan; Sagici, Ozge; Ozdogar, Asiye Tuba; Yigit, Pinar; Baba, Cavid; Ozakbas, SerkanBackground and Purpose: Urinary incontinence is a common symptom in people with multiple sclerosis. The primary aim was to investigate feasibility of telerehabilitation-based pelvic floor muscle training (Tele-PFMT) and compare its effects on leakage episodes and pad usage with home exercise-based pelvic floor muscle training (Home-PFMT) and control groups. Methods: Forty-five people with multiple sclerosis with urinary incontinence were randomized into 3 groups. Tele-PFMT and Home-PFMT groups followed the same protocol for 8 weeks, but Tele-PFMT performed exercises 2 sessions/week under a physiotherapist's supervision. The control group did not receive any specific treatment. Assessments were made at baseline, weeks 4, 8, and 12. Primary outcome measures were feasibility (compliance to exercise, patient satisfaction, and number of participants included in the study), number of leakage episodes, and pad usage. Secondary outcomes included severity of urinary incontinence and overactive bladder symptoms, sexual function, quality of life, anxiety, and depression. Results: Participant eligibility rate was 19%. Patient satisfaction and compliance to exercise were significantly higher in Tele-PFMT than in Home-PFMT (P < 0.05). No significant differences in the change of leakage episodes and pad usage were found between Tele-PFMT and Home-PFMT. No significant differences in secondary outcomes were found between PFMT groups. Participants in both the TelePFMT and Home-PFMT groups had significantly better scores for some measures of urinary incontinence, and overactive bladder and quality of life in compared with the control group. Discussion and Conclusions: Tele-PFMT was feasible and acceptable in people with multiple sclerosis, and this mode of delivery was associated with greater exercise compliance and satisfaction compared with Home-PFMT. However, Tele-PFMT did not exhibit superiority in terms of leakage episodes and pad usage compared with Home-PFMT. A large trial comparing Home-PFMT and Tele-PFMT is warranted.Conference Object Recommendation Regarding Health-Related Quality of Life Measurement in People With Multiple Sclerosis(Sage Publications Ltd, 2023) Ozdogar, Asiye Tuba; Sagici, Ozge; Ozcelik, Sinem; Dastan, Seda; Baba, Cavid; Ozakbas, SerkanArticle The Relationship Between Work Difficulties and Physical Disability, Cognitive and Social Cognitive Impairment and Subcortical Gray Matter Atrophy in Persons With Multiple Sclerosis(Springer Heidelberg, 2024) Aslan, Taha; Ozdogar, Asiye Tuba; Sagici, Ozge; Ozakbas, SerkanBackground Multiple sclerosis (MS) is commonly associated with work difficulties. This study aimed to examine the relationship between work difficulties and physical disability, cognitive and social cognitive impairment, and subcortical gray matter (scGM) atrophy in pwMS. Methods Thirty-three employees with MS underwent assessments with Multiple Sclerosis Work Difficulties Questionnaire-23 MSWDQ-23. Physical disability was measured using EDSS, Timed 25-Foot Walk (T25FW), 2-Minute Walking Test (2-MWT), the Nine-Hole Peg test (N-HPT), and 12-item Multiple Sclerosis Walking Scale (MSWS-12). Cognitive functions were evaluated with Brief International Cognitive Assessment in MS (BICAMS), social cognition with Facial Emotion Identification (FEI), Reading the Mind in the Eyes Test (RMET), and Empathy Quotient (EQ). Anxiety and depression were assessed using Hospital Anxiety and Depression Scale (HADS). The association between variables was analysed using Spearman's correlation coefficient. GM volumes were calculated from 3T MRI data using Freesurfer, their potential relationship with work difficulties were evaluated through a linear regression model. Results MSWDQ-23 was strongly correlated with T25FW and MSWS-12 (p<0.01), moderately correlated with EDSS, 2MWT, HAD, BICAMS, and EQ (p<0.05). According to the linear regression model the decrease in volumes of total GM and scGM, bilateral Thalamus, bilateral Hippocampus, left Putamen, and right Caudate related with the severity of work difficulties (R-2=0.815, p=0.25). Conclusion This study provides valuable insights into the multifaceted nature of work difficulties experienced by pwMS. It suggests that not only physical disability but also other factors, such as mood, cognition, empathy, and cortical and subcortical gray matter atrophy may contribute to work difficulties among pwMS.Conference Object Revolutionizing Multiple Sclerosis Treatment: Unleashing the Power of the Symbol Digit Modalities Test To Optimize Cognitive Function(Sage Publications Ltd, 2023) Sagici, Ozge; Karakas, Hilal; Ozdogar, Asiye Tuba; Baba, Cavid; Ozakbas, SerkanConference Object Telerehabilitation From the Perspective of People With Multiple Sclerosis(Sage Publications Ltd, 2023) Dastan, Seda; Ertekin, Ozge; Ozdogar, Asiye Tuba; Sagici, Ozge; Ozakbas, SerkanConference Object What Upper Extremity Functions Manifest in People With Ms? Presentation of Big Data From Turkey(Sage Publications Ltd, 2023) Ozdogar, Asiye Tuba; Sagici, Ozge; Dastan, Seda; Aslan, Taha; Baba, Cavid; Ozakbas, Serkan
