Browsing by Author "Sahin, I"

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Cesarean Delivery Rates in Adolescent Pregnancy
(Parthenon Publishing Group, 2005) Zeteroglu, S; Sahin, I; Gol, K
Objectives To investigate the rates of cesarean deliveries in two different hospitals, which serve different populations in Turkey. Methods The study was conducted at two centers, one of which is a university hospital in a rural area and the other a community hospital in capital city, for 5 years (1999-2003). The subjects were < 18 years old adolescent mothers. The adult controls ( >= 18 years) were further divided in two age groups: 18-35 years and > 35 years. Results A total of 40,391 pregnant women were evaluated in both hospitals. Cesarean delivery rates in adolescent pregnancies were not higher than adults. Moreover, in community hospital, cesarean delivery rate in adolescents was significantly lower (17.12% vs. 28.84%). Conclusions We concluded that, the cesarean deliveries are not increased, and even decreased in adolescent pregnancies and biological immaturity is not a significant problem in adolescent pregnancy.
Mild Renal Injury in Behcet's Disease
(Taylor & Francis Ltd, 2004) Sahin, I; Noyan, T; Karaman, E; Yalçinkaya, AS; Metin, A; Akpolat, T
Aim: The aim of this study is to investigate the frequency of microalbuminuria and abnormal urinary beta(2)-microglobulin excretion in patients with Behcet's disease (BD). Materials and Methods: Twenty-eight patients and 27 healthy controls were included in this study. Urine albumin/creatinine and beta(2)-microglobulin/creatinine ratios were calculated. Results: The frequency of microalbuminuria and abnormal urinary beta(2)-microglobulin excretion was higher among patients with BD than in control group, but this was not statistically significant (p>0.05). Conclusion: Microalbuminuria and abnormal beta(2)-microglobulin excretion are markers of renal injury, which have not been investigated in BD previously. Renal injury in BD is more frequent than has been recognized and it is most often in mild nature.
The Prevalence of Pancreatitis in Organophosphate Poisonings
(Arnold, Hodder Headline Plc, 2002) Sahin, I; Onbasi, K; Sahin, H; Karakaya, C; Ustun, Y; Noyan, T
Objective: The aim of this study was to evaluate the prevalence of pancreatitis in cases of organophosphate (OP) poisonings admitted to Yuzuncu Yil University Teaching Hospital over an 18-month period. Materials and Methods: A total of 47 patients of acute poisoning with OP insecticides attended the Emergency Department of the Yuzuncu Yil Medical School Hospital, from May 1999 to December 2000, and were prospectively studied. Serum amylase and lipase levels were studied with colorimetric assay. Serum SGOT, SGPT, LDH, CPK, K levels, leukocyte count and total hospitalization days were also evaluated. Results: Four of 47 patients had obviously elevated amylase and lipase levels (amylase > 300 U/L, lipase > 60 U/L). Only two of the patients with amylase levels between 100 and 300 V/L had also elevated levels of lipase. None of the patients with normal amylase levels had elevated levels of lipase. A total of 12.76% was diagnosed as acute pancreatitis. Conclusion: Acute pancreatitis as a complication of OP intoxication is not a rare condition. In order to improve the outcome of OP poisoning, early diagnosis of acute pancreatitis is important and serum levels of amylase and lipase should be routinely considered carefully. In acute pancreatitis, serum levels of SGOT, SGPT, LDH and leukocyte counts may also be found to be elevated. However, serum K levels are only slightly decreased.
Raynaud's Phenomenon in a Healthy Turkish Population
(Springer London Ltd, 2005) Onbasi, K; Sahin, I; Onbasi, O; Üstün, Y; Koca, D
Raynaud's phenomenon (RP) is a vasospastic disease and is characterized by ischemia of the digits, nose, and ears. The vasospasm can be triggered by cold weather, cold water, or emotional stress and is followed by triphasic color changes. First white color (ischemia), then blue color (congestion and cyanosis), and finally red color change (reactive hyperemia) can be observed. The prevalence is reported to be between 0.5 and 20% in different studies and is dependent on genetic, occupational, and environmental factors. The purpose of our study was to determine the prevalence of RP in an eastern part of Turkey among healthy subjects. A total of 768 people were included in the study. This cross-sectional study was conducted between April 2003 and October 2003 at the University Hospital and at the State Hospital in Van, Turkey. The participants were interviewed and examined to diagnose RP and a questionnaire and color charts were used. Of these 768 patients, 25 women and 20 men were diagnosed to have RP. A female predominance (25/20) was observed. Their mean age was 24.78 +/- 5.71 years. The prevalence of RP was 5.9% in our study population.
Renal Involvement in Brucellosis
(Oxford Univ Press, 2005) Sahin, I; Arabaci, F; Eminbeyli, L; Ilhan, M; Onbasi, K; Sahin, HA
The Serum Vitamin C Levels in Behcet's Disease
(Yonsei Univ Coll Medicine, 2003) Noyan, T; Sahin, I; Sekeroglu, MR; Dülger, H
Behcet's disease (BD) is a chronic inflammatory disorder of unknown aetiology, and recognised as a multi-system vasculitis. It has been postulated that an imbalance of the oxidant and antioxidant systems related to the disease are important in its pathogenesis. Previous publications have reported increased levels of enzymatic antioxidant defence systems in patients with BD. The non-enzymatic antioxidant systems, including vitamin C and uric acid, were looked for in the present study. For this aim, the serum malondialdehyde (MDA), an end product of lipid peroxidation, and vitamin C and uric acid, as endogenous antioxidants, were determined in 20 patients with BD (11 in active and 9 in inactive periods) and 20 healthy subjects. The MDA level was significantly higher in both the active and inactive period patients compared with the control group (p < 0.001, p < 0.05, respectively). The MDA level was also significantly higher in the active period patients compared with the inactive period patients (p < 0.05). The vitamin C levels were significantly lower in both the active and inactive period patients compared with the control group (p < 0.001, p < 0.05, respectively). There was no significant difference in the vitamin C level between the active and inactive period patients (p > 0.05). There was also no significant difference in uric acid levels between the groups (p > 0.05). In the patients group, a negative correlation was found between the levels of serum MDA and vitamin C (r=-0.517; p < 0.05). Our results indicate that decreased vitamin C and increased MDA levels reflect the increased levels of oxidative stress in BD patients, and this situation may be important in relation with its pathogenesis.
Sociodemographic Factors in Organophosphate Poisonings: a Prospective Study
(Sage Publications Ltd, 2003) Sahin, HA; Sahin, I; Arabaci, F
The sociodemographic features of organophosphate poisonings (OPPs) in the east Anatolian region of Turkey were investigated in this study. All OPPs admitted to the Emergency Department of Yuzuncu Yil University Medical Faculty Hospital in Turkey from 1 April 1999 to 31 August 2001 were prospectively studied. Data collected included age, gender, education, employment and marital status, socioeconomic levels, time and route of exposure of the toxic agents, treatment before admission, duration of hospitalization and complications. The proportion of OPPs was 15.1% among 564 poisonings. Fifty-seven (67.1%) patients were female, 28 (32.9%) were male. Fifty-six (65.9%) cases were attempted suicides and 29 cases (34.1%) were due to accidental events. Mean age was 22.1 +/- 9.2 years in the suicidal cases and 43 (76.8%) of them were less than 24 years ( P = 0.001). Among the suicide attempts, 29 (51.8%) patients were unmarried and 43 ( 76.8%) patients were female. The attempted suicide proportion was 46.4% in men and 75.4% in women ( P = 0.008). Eighty per cent of cases had a primary education level or were illiterate and 78.8% of the patients were in the lower socioeconomic status. The patients' mean arrival time to the hospital after poisoning was 4.4 +/- 3.7 (1-15) hours and mean hospitalization duration was 4.9 +/- 4.1 (1-32) days. Exposure routes were gastrointestinal in 75 (88.2%), respiratory in five (5.9%), dermal in four (4.7%) and both dermal and respiratory in one case (1.2%). Seventeen patients (23.5%) were admitted to the ICU and four ( 4.7%) of them died. In conclusion, OPPs especially affected young unmarried females, and most of them were due to attempted suicide. As OPP is the important cause of morbidity and mortality in the region, therapy should be started as early as possible so undesirable consequences can be avoided.