Browsing by Author "Sarikaya, M."

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Antioxidant Effect of Omega-3 Fatty Acids on Exercise-Induced Oxidative Stress in Rats
(Verduci Editore s.r.l, 2023) Sarikaya, M.; Aslan, M.; Çinar, V.; Çibuk, S.; Selçuk, M.; Embiyaoğlu, N.M.; Öğe, B.
OBJECTIVE: The aim of this study is to examine the effects of omega-3 supplementation on Catalase (CAT) activity, Malondialdehyde (MDA), advanced oxidation protein products (AOPP) and reduced glutathione (GSH) levels in long-term aerobic exercises in rats. MATERIALS AND METHODS: 28 male Wistar albino rats (8 weeks old, 220-350 g body weight) were included in the study. The rats were given treadmill exercise for 20 minutes at an average speed of 15 cm/s, 5 days a week, for 8 weeks. The experiment was terminated at the end of the eighth week. Blood samples were taken. CAT, MDA, AOPP and GSH analyses were performed. SPSS v. 21 package program was used in the analysis of the data. The distribution of the data was examined with the normality homogeneity test, and it was determined that it was a normal distribution. As a result, the One-Way ANOVA test, one of the parametric tests, was used. Tukey test was used to determine the difference between groups. Significance levels were evaluated as (p < 0.05). RESULTS: Statistical analysis showed a statistically significant difference between groups in CAT, MDA and GSH levels (p < 0.05), while there were no differences between the groups in AOPP levels (p > 0.05). CONCLUSIONS: In the conclusion of the study, it was determined that omega-3 supplementation caused a decrease in MDA level, an increase in CAT activity and GSH level in rats exposed to chronic long-term exercise. Thus, it can be said that omega-3 supplementation in chronic long-term exercise will provide antioxidant protection against potential oxidative damage. © 2023 Verduci Editore s.r.l. All rights reserved.
The Effect of 8 Week Resistance Exercise on Some Anthropometric Measurements and Body Composition To Sedentary Women
(Natl Olympic Committee Ukraine, Kharkov Regional Branch, 2019) Turgut, M.; Bagir, S.; Sarikaya, M.; Tinaz, U.
Purpose: The aim of this study is to determine the effect of resistance exercise program applied to eight weeks on some anthropometric measurements and body composition in sedentary women. Material: Fifteen volunteer women with a mean age of 20.67 +/- 1.29 years were included in the study. After asking the participants whether there are any health problems before the exercise program, detailed information was given and the exercises were implemented correctly and efficiently. Participants were given a 45-minute resistance exercise for 3 days a week. In order to compare the data obtained (Wilcoxon Test) was applied to compare descriptive statistics with pre- and post-exercise values via using SPSS 22.0. Before and after the exercise program (Weight, Hip circumference, calf circumference, chest circumference, waist circumference, shoulder circumference and BMI) were measured. Results: According to the findings of the study, it was determined that there was a significant difference between the anthropometric measurement and body composition values of the exercise program applied before and after the exercise program of the participating women (p > 0.05). Conclusions: In conclusion, the effects of regularly performed exercises, especially aerobic and resistance exercises done for women, on persons are seen in the literature and research essays. Deterioration in the body composition of women is seen depending on age and excessive weight.
The Effect of 8 Week Resistance Exercises on Blood Lipids and Blood Sugar Levels in Sedentary Women
(South Ural State Univ, Scientific Research dept, 2019) Turgut, M.; Bagir, S.; Bozkus, T.; Talaghir, L. G.; Sarikaya, M.
Aim. The purpose of this study was to investigate the effects of an eight-week resistance exercise program on blood fats and blood sugar in sedentary women. The study included 20 volunteers with a mean age of 31.70 +/- 3.81 years. Materials and methods. Blood samples were taken by the experts in the appropriate laboratory environment in the morning before and after the resistance exercise program, which was administered 60 minutes 3 days a week for 8 weeks in the mornings on an empty stomach. Dependent groups t-test (Paired Sample T-Test) was applied to compare descriptive statistics with pre- and post-exercise values by using SPSS 22.0 package program. Results. There was a significant difference between GLU, Triglyceride, HDL, LDL, and total cholesterol levels before and after the resistance exercise program (p > 0.05). Conclusions. Resistance exercises have a positive effect on blood sugar and blood fat change. Therefore, we think that it can be used as protection from cardiovascular diseases, and if these exercises are applied regularly, they will have many positive results in terms of health.
Effect of Zinc Supplement and Weight Lifting Exercise on Thyroid Hormone Levels
(Association of Physiologists and Pharmacologists of India, 2017) Cinar, V.; Akbulut, T.; Sarikaya, M.
The aim is to determine the effect of 6-week zinc supplement and weight lifting exercise on the thyroid hormone levels. Study participants were 40 males, age between 18-22 years; 20 sedentaries and 20 individuals who do physical exercises. Subjects were divided equally into 4 groups. Which is: The sedentary group (S) control group,Sedentary group which is supplied withonly zinc (Z+S),Training Group which is supplied with zinc (Z+T) and Athletes Group that train regularly (T). Zinc supplement was given 3mg/kg/day/6 weeks as oral. At the beginning of the study and after 6-week training, the blood samples were drawn from the participants before and after the treatments; and TSH, FT3 and FT4 levels of the participants were determined. It was identified that thyroid values of groups which were supplied with zinc decreased owing to the training and zinc supplement. Consequently, it is thought 6-week zinc supplement and exercise can contribute to the athletes’ performance by changing thyroid values positively. © 2017, Association of Physiologists and Pharmacologists of India. All rights reserved.
Effects of Curcumin Administration on Nesfatin-1 Levels in Blood, Brain and Fat Tissues of Diabetic Rats
(verduci Publisher, 2021) Algul, S.; Ozcelik, O.; Oto, G.; Sarikaya, M.; Goceroglu, R. T.; Embiyaoglu, N. M.; Akcan, A. G.
OBJECTIVE: We evaluated the efficacy of curcumin administration on blood glucose levels and its relationship with nesfatin-1 levels in blood brain and adipose tissue of streptozotocin-induced diabetic rats. MATERIALS AND METHODS: A total of 28 male rats were divided into four groups: control group, type 2 diabetes mellitus (DM) group, control plus curcumin group and type 2DM plus curcumin group. After fifteen days, blood samples were collected from sacrificed rats. Nesftain-1 levels were analysed from blood, brain, and fat tissues of rats in all groups. RESULTS: Nesfatin-1 level was found to be significantly lower in blood, brain and fat tissues of type 2 DM rats compared to the control group. A significant decrease in fasting blood glucose levels was observed in the curcumin administration group compared to type 2 DM group. Improvement of fasting blood glucose level was accompanied by improvement of nesfatin-1 levels in blood, brain, and fat tissues. CONCLUSIONS: As expected, curcumin administration caused significant improvement in fasting blood glucose levels. However, for the first time, we found marked improvements in nesfatin-1 levels in blood, brain, and fat tissues of type 2 DM rats. Thus, considering the crucial role of nesfatin-1 in regulation of glucose metabolism, it is logical to expect an interactive relationship between curcumin and nesfatin-1.