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Browsing by Author "Sayan, Sena"

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    Energy Drinks May Affect the Ovarian Reserve and Serum Anti-Mullerian Hormone Levels in a Rat Model
    (Galenos Yayincilik, 2021) Elci, Erkan; Elci, Gulhan Gunes; Cim, Numan; Aras, Ibrahim; Sayan, Sena; Yildizhan, Recep
    Objective: Energy drinks have an impact on concentration levels, physical performance, speed of reaction, and focus, but these drinks cause many adverse effects and intoxication symptoms. The main goal of this study was to determine the effect of energy drink consumption on ovarian reserve and serum anti-mullerian hormone (AMH) levels. Materials and Methods: Female Wistar albino rats (n=16) were included and randomized into two groups (n=8). Serum AMH levels were checked before and after energy drinks were given. Eight weeks later, the ovaries and uteruses of the rats were analyzed histopathologically. The number of follicles in the ovaries was counted. Results: The total number of the preantral plus small antral follicles, which show the ovarian reserve, was decreased at the end of eight weeks in both the control group and the energy drink group. There was a statistical difference between them (p=0.021). Also, there was a statistically significant difference in the initial/final AMH (ng/mL) reduction levels between the control group and the energy drink group (p=0.002). AMH levels were decreased more in the energy drink group. Conclusion: The consumption of energy drinks can lead to a decrease in ovarian reserve and AMH values and may cause weight gain.
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    Article
    Menopoza Güncel Yaklaşım
    (2017) Yildizhan, Recep; Sayan, Sena
    Yaşam süresinin artması ile fizyolojik menopoz dönemi de uzamıştır. Vazomotor semptomlar başta olmak üzere bir çok sağlık sorunu gelişecektir. Tüm bunlara karşın geliştirilen medikal ve paramedikal yöntemler sık olarak güncellenmektedir. Önceki yıllarda olduğu gibi sık reçete edilmemekle beraber hormon replasman tedavisi halen bu semptomların giderilmesinde en önemli yöntemdir.
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    Two Years Follow-Up of Patients With Abnormal Uterine Bleeding After Insertion of the Levonorgestrel-Releasing Intrauterine System
    (Karger, 2018) Cim, Numan; Soysal, Sunullah; Sayan, Sena; Yildizhan, Begum; Karaman, Erbil; Cetin, Orkun; Yildizhan, Recep
    Aim: To evaluate the efficacy and safety of levonorgestrel-releasing intrauterine system (LNG-IUS) in the long-term treatment of heavy menstrual blood loss in women unrelated to intrauterine pathology. Methods: One hundred and six parous women aged 33-48 years with recurrent heavy menstrual bleeding (HMB) participated in this study. The women were followed up for 24 months and were assessed for intensity of bleeding both for pre- and post-insertion periods. An LNG-IUS was inserted in each patient within 7 days of the start of menstrual flow. The women were followed up at 1, 3, 6, 12, 18, and 24 months following the insertion of the intrauterine device. Results: One hundred and two women completed the follow-up period and had a significant reduction in the amount of menstrual blood loss. The LNG-IUS was well tolerated by all women. Pre-treatment of the use of the LNG-IUS, endometrial biopsy patterns for irregular proliferative endometrium and for atypical simple hyperplasia were 34/106 (32.08%) and 61/106 (57.55%) respectively and after treatment no abnormal pathologic findings were determined (p < 0.001). Conclusion: Our findings indicate that the LNG-IUS is effective for significantly reducing the amount of menstrual blood loss in women with HMB. (c) 2017 S. Karger AG, Basel