Browsing by Author "Sayarlioglu, Hayriye"

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Analysis of Factors Associated With Survival in Advanced Stage Gastric Adenocarcinoma
(Kare Publ, 2005) Alici, Suleyman; Kaya, Serap; Izmirli, Mustafa; Tuncer, Ilyas; Dogan, Ekrem; Ozbek, Hanefi; Sayarlioglu, Hayriye
In this study, 138 patients with high grade gastric adenocarcinoma who were admitted to Yuzuncu Yil University, Medical School, Department of Medical Oncology between September 1999 and April 2002 were retrospectively evaluated in terms of the effects of clinicopathological parameters and treatment approaches on survival by single and multiple variable analyses. Patients histopathologically diagnosed as gastric adenocarcinomas with stage IV M0 (without distant organ metastasis) or stage IV M1 (with distant organ metastasis) were included in the study. Mean age of the patients was 61.1 (34-84), 64.6% male and 35.5% female. The ratio of patients with a performance score of 2-3 was 55%. The BMI was below 20 in 53.6% of the patients. According to histological grading, 41.9% of patients had indifferentiated adenocarcinoma, mucinous cell adenocarcinoma or signet ring cell adenocarcinoma. 84% of patients were clinically at stage IV M1. The percentage of patients with tumor localized upper 1/3 of stomach was 60.8%. While 19.6% of patients had received surgical treatment, 47% of the patients had received chemotherapy as adjuvant or paliative purposes. The percentage of the patients who responded to the therapy (complete response + partial response + stable response) was 39% and the percentage of patients who had progression was 7.2%. Overall median survival time was 3.1 months and three years survival rate was 8%. At single variable analysis, BMI, clinical stage, surgery, type of surgery and serum level of albumin were significant prognostic factors related to overall median survival time. Gender, clinical stage, surgery, type of surgery, hemoglobine concentration and serum level of albumin were found to be significant prognostic factors related to survival without progression (p<0.05). The factors found to be significant related to overall survival rate in single variable analysis were reevaluated in multiple variable analysis. No surgical treatment, paliative surgery (compared to radical surgery), BMI below 20 were found to be the statistically significant poor prognostic factors related to survival. The factors found to be significant related to survival without progression in single variable analysis were evaluated in multiple variable analysis and no surgical treatment (compared to surgery), male gender (compared to female) were found to be statistically significant poor prognostic parameters. In terms of both overall survival and survival without progression, whether performing surgery or not was statistically most significant independent prognostic factor. In conclusion, no surgical treatment, paliative surgery instead of radical surgery, and BMI below 20 on first admission were determined as poor prognostic factors related to survival in patients with high grade gastric adenocarcinoma.
Cloudy Dialysate Due To Lercanidipine
(Oxford Univ Press, 2006) Topal, Cevat; Sayarlioglu, Hayriye; Dogan, Ekrem; Erkoc, Reha; Soyoral, Yasemin
Comparative Effects of Carvedilol and Lercanidipine on Ultrafiltration and Solute Transport in Capd Patients
(Taylor & Francis Ltd, 2009) Topal, Cevat; Erkoc, Reha; Sayarlioglu, Hayriye; Dogan, Ekrem; Beyenik, Huseyin
Background. Peritonitis, the type of buffer used in the dialysate, continue ambulatory peritoneal dialysis (CAPD) of greater than two years duration, increased exposure to dialysate glucose, diabetes mellitus, and the use of beta blockers may contribute to impaired ultrafiltration. Objectives. The aim of the present study is to compare the effects of a calcium-channel blocker and a beta-blocker on the peritoneal transport and clearance. Methods. We studied 48 patients with ESRD on chronic peritoneal dialysis, included 27 females and 19 males with mean age 42.6 +/- 16.4 years. Two patients were excluded from the study due to peritonitis. Patients were treated either with carvedilol or lercanidipine. In all patients; peritoneal equilibration test ( PET), ultrafiltration (UF), Kt/V ratio, creatinine clearance (CrCl), systolic blood pressure, diastolic blood pressure, serum BUN, creatinine, glucose, sodium, potassium, albumin, cholesterol, and triglyceride values were obtained before and after 8 weeks from the start of the drug treatment. Results. Lercanidipine and carvedilol showed a good antihypertensive effect in CAPD patients. Both drugs had a good tolerability profile and showed no effect on plasma lipids. There were no differences in terms of PET, ultrafiltration, Kt/V ratio, CrCl, systolic blood pressure, diastolic blood pressure, serum BUN, creatinine, glucose, sodium, and potassium values between both patient groups. After antihypertensive treatment, neither group showed a difference in the above-mentioned parameters (p > 0.05) except potassium, which was significantly higher in the carvedilol group (p < 0.05). Conclusions. In CAPD patients. short-term usage of carvedilol has no effect on ultrafiltration and solute transport like lercanidipine. Both drugs showed a good antihypertensive effect.
Comparison of Argon Laser Photocoagulation-Induced Cutaneous Inflammation and Skin Pathergy Test in Behcet's Disease
(Springer, 2010) Sayarlioglu, Mehmet; Calka, Omer; Cinal, Adnan; Sayarlioglu, Hayriye; Akdeniz, Necmeddin; Topcu, Nazan; Gul, Ahmet
Nonspecific increased inflammatory response is an important feature of Behcet's disease (BD). The skin pathergy reaction (SPR) which tests this hyperreactivity in the skin is frequently used as a diagnostic tool. This study aims to investigate the argon laser photocoagulation (ALP)-induced cutaneous inflammation in BD patients and controls and also to compare the results with the skin pathergy test (SPT). The study group consisted of 35 patients with BD and 28 healthy volunteers. The ALP was applied to the left forearms of all cases from 20-cm distance (2,000 mW, 100 A mu m) with exposure times ranging from 0.2 to 0.7 s with 0.1-s increments. Also, a SPT with three prics was performed to both forearms of all cases. The ALP-induced cutaneous inflammation and SPT were evaluated and scored with the same method at 48 h, and the SPR scores of 2+ and above was accepted as positive. Positive results as defined above were found in eight cases (23%) with the ALP and in nine (26%) with the SPT in patients with BD. There was no clear correlation between the ALP and SPT results and also between the exposure time to laser beam and SPR scores. The preliminary results of this study reveal that ALP can induce a skin hyperreactivity similar to the needle prick-induced SPR in patients with BD. We, herein, showed that ALP can induce skin inflammation with its thermal effect and without any inoculation of antigen in BD. This method would help to develop another experimental method to investigate the cutaneous inflammation in BD.
Diurnal Rhythm of Urinary Calcium Excretion in Adults
(Taylor & Francis inc, 2008) Topal, Cevat; Algun, Ekrem; Sayarlioglu, Hayriye; Erkoc, Reha; Soyoral, Yasemin; Dogan, Ekrem; Cekici, Saliha
Twenty-four-hour urinary calcium excretion is normally the equivalent of daily calcium intake, and varies between 200-300 mg/dL with a calcium/creatinine ratio of 0.07-0.15. In this study, we aimed to investigate the diurnal rhythm of calcium excretion in healthy individual. Forty subjects (30 male, 10 female) were involved into the study. The spot urine samples were taken at 08: 00, 14: 00, and 22: 00 together with a 24-hour collection. Mean spot urinary calcium levels at 08: 00, 14: 00, and 22: 00 were 12.39 +/- 8.19, 12.97 +/- 8.37, and 16.95 +/- 10.39 mg/dL, with calcium/creatinine ratios of 0.104 +/- 5.261, 0.119 +/- 7.85, and 0.133 +/- 8.17, respectively. Twenty-four-hour urinary calcium excretion was 12.74 +/- 7.31 mg/dL with a calcium/creatinine ratio of 0.111 +/- 5.41. The values at 08: 00, 14: 00, and of 24-hour collection were statistically similar (p > 0.05), but the nighttime values were significantly elevated (p < 0.05). In conclusion, calcium excretion is increased at night, and urinary calcium measurements should be interpreted accordingly.
Effect of Depot Oral Cholecalciferol Treatment on Secondary Hyperparathyroidism in Stage 3 and Stage 4 Chronic Kidney Diseases Patients
(Taylor & Francis Ltd, 2008) Dogan, Ekrem; Erkoc, Reha; Sayarlioglu, Hayriye; Soyoral, Yasemin; Dulger, Haluk
By the time patients require dialysis replacement therapy, nearly all chronic kidney diseases (CKD) patients are affected with uremic bone diseases. High-turnover osteodystrophy can be prevented; patients with CKD should be monitored for imbalances in calcidiol (25 OH vitamin D), calcium, and phosphate homeostasis. We aimed to determine the effect of a monthly oral 300,000 IU vitamin D-3 (cholecalciferol) supplementation on the uremic bone diseases (UBD) markers such as iPTH and alkaline phosphatase in CKD patients. Among a total of 70 patients under treatment in the nephrology unit, 40 predialysis CKD patients (mean age of 49 14, male/female 20/20) were included the study. The patients were randomly divided into two groups. Treatment group included 20 patients (mean age of 51 +/- 14, male/female 9/11), and the control group comprised 20 patients (mean age of 47 +/- 14, male/female 9/11). Treatment group patients were given a single dose of Devit3 ampoule (300,000 U cholecalciferol) per month orally way. Patients in the control group did not take any vitamin D for a month. The level of calcidiol was lower than normal range in two groups. After a month, treatment group patient's calcidiol increased statistically significant (6.8 +/- 3.5 to 17.8 +/- 21.4 ng/mL, p < 0.001). After a month, iPTH level decreased in the treatment group statistically significantly (368 +/- 274 to 279 +/- 179 pg/ml, p < 0.001). At the 30(th) day of the treatment, in 9/20 of the treatment group patients (45%), the iPTH value decreased at least 30% (p < 0.001). We suggest that oral depot cholecalciferol treatment causes a statistically significant decrease of serum iPTH level but does not cause a statistically significant change in Ca, P, ratio of CaxP, or urinary calcium creatinine rate in UBD predialysis CKD. This treatment can be used safely for the predialysis CKD patients, along with the cautious control of serum calcium and phosphor.
The Effect of Zofenopril on the Peritoneal Membrane in Capd Patients
(Oxford Univ Press, 2006) Sayarlioglu, Hayriye; Dogan, Ekrem; Erkoc, Reha; Soyoral, Yasemin; Kara, Pinar; Baykal, Sanem; Guducuoglu, Huseyin
Effects of Low Sodium Dialysate in Chronic Hemodialysis Patients With Hypertension
(Oxford Univ Press, 2007) Esen, Ramazan; Erkoc, Reha; Sayarlioglu, Hayriye; Soyoral, Yasemin; Dogan, Ekrem; Sekeroglu, Ramazan; Begenik, Huseyin
Effects of Low Sodium Dialysate in Chronic Hemodialysis Patients: an Echocardiographic Study
(Taylor & Francis Ltd, 2007) Sayarlioglu, Hayriye; Erkoc, Reha; Tuncer, Mustafa; Soyoral, Yasemin; Esen, Ramazan; Gumrukcuoglu, Hasan Ali; Sayarlioglu, Mehmet
Background. Chronic kidney disease (CKD) and hemodialysis (HD) patients who cannot restrict sodium consumption in their diets sometimes develop significant saline excess and hypertension between dialyses. This study assessed the effect of relatively low sodium dialysate dialysis on changes of echocardiography in hemodialysis patients. Methods and Results. Eighteen patients with end stage renal failure on chronic HD were studied (8 females, 10 males) with a mean age 48.3 +/- 14.6 (24-70) years. The mean time on HD was 30.8 +/- 14.0 (12-60) months. Patients with hematocrit levels under 24% were excluded from the study. In all patients, echocardiography was performed thrice weekly before and after eight-week HD treatment with low sodium dialysate hemodialysis by the same operator (135 mEq/L for patients with sodium levels less than 137, 137 for patients with sodium levels over 137). Left atrium (LA) and left ventricle (LV) volumes and ejection fractions were measured, specifically: LV systolic diameter (LVSD), LV diastolic diameter (LVDD), interventricular septum (IVS), tricuspid regurgitation (TR), mitral regurgitation (MR), pulmonary artery pressure (PAP), and inferior vein cava diameter (IVCD). Results. In terms of echocardiographic parameters, LVSD, TR, PAP, and IVCD were statistically decreased after low-sodium dialysate treatments (p = 0.002, 0.04, 0.013, and 0.00, respectively). Predialysis systolic and diastolic blood pressure (BP), post-dialysis systolic blood pressure, and interdialytic weight gain was statistically decreased when compared to basal levels (p = 0.00, p = 0.011, p = 0.022, p = 0.001, respectively). Conclusion A reduction of the dialysate sodium concentration based on the predialysis sodium levels of the patients could reduce the systolic BP and decrease the volume load on the heart as assessed by echocardiography. Within this short period, postdialysis diastolic BP could not be lowered. The effect of this approach should be studied in broad and lengthy series.
Epidemiology of Glomerulonephritis in the City of Van: Pathological Findings of 129 Cases
(Turk Nefroloji Diyaliz Transplantasyon dergisi, 2005) Sayarlioglu, Hayriye; Erkoc, Reha; Topal, Cevat; Dogan, Ekrem; Ozen, Suleyman; Bayram, Irfan; Ugras, Serdar
Epidemiologies of nephropathies differ in different geographical and developmental areas. In order to determine the region's adult nephropathy profile, consecutive renal biopsies performed between January 1997 and December 2003 were reviewed. There were 129 cases (M 63, F 66, mean age 32.2 +/- 15.6), of which 115 had adequate biopsies. Lupus nephritis formed the largest diagnostic entity (23.3%). When lupus cases are excluded, the most common form of glomerulonephritis is membranoproliferative form (27.6%). While high lupus nephritis incidence may be due to our routine biopsy protocol for these patients, relatively higher incidence of MPGN may represent higher prevalences of different infections in the region.
Gall Bladder Perforation, a Rare Complication of Continuous Ambulatory Peritoneal Dialysis: Case Report
(Turk Nefroloji Diyaliz Transplantasyon dergisi, 2007) Sayarlioglu, Hayriye; Soyoral, Yasemin; Dogan, Ekrem; Kotan, Cetin; Asian, Murat; Baser, Murat; Erkoc, Reha
Continuous ambulatory peritoneal dialysis (CAPI2b is a widely used method al the treatment of end stage Fero' failure patients, Mechanical and meoholo cornplications can be detected during CAPD treatment. Perforwions of inusanderpinal organs are rarely seen complitations CAR) benefits We presented a CAPD patient anth gall bladder perfuranan.
Gebelikte Akut Böbrek Yetersizliği
(2006) Sayarlioglu, Hayriye; Dilek, İmdat; Esen, Ramazan; Topal, Cevat; Erkoç, Reha; Doğan, Ekrem
Gelişmekte olan ülkelerde alınan tüm önlemlere rağmen obstetrik kaynaklı akut böbrek yetersizliği (ABY) halen önemli bir problemdir. Bu çalışmada 2000-2004 yılları arasında ABY tanısı ile izlenen 402 hastadan obstetrik nedenli olan 37 olgu değerlendirildi. Bu hastalarda ABY; %40.5 (n=15) doğum sonu kanamaya, %24.2 (n=9) eklampsi ve HELLP sendromuna, % 13.5 (n-5) sepsise, %13.5 (n=5) yeni tanı kronik böbrek yetersizliğine bağlandı. Birinde kronik hipertansiyon zemininde gelişen preeklanıpsi mevcuttu. İki vakada ise ABY düzelmeyince biyopsi yapılarak akut kortikal nekroz tanısı kondu. Olgulardan biri ise sepsise bağlı solunum yetersizliği nedeniyle kaybedildi. Kortikal nekrozu olan 2 vaka kronik hemodiyaliz programına alındı. Gebelik öncesinde saptanmamış, doğum sonu böbrek yetersizliği olarak kliniğimize başvurup tetkik edildikten sonra bilateral atrofık böbrek tespit edilip, kronik böbrek yetmezliği olduğu anlaşılan 5 vaka saptandı. Hastaların 17 sinde diyaliz ihtiyacı gelişti. Diğer hastaların tamamı tanıdan itibaren en geç 6 ay içinde tamamen iyileşti. Obstetrik kaynaklı ABY'de mortalite ve morbidije halen oldukça yüksektir. Obstetrik Kaynaklı ABY'yi önlemek için önlemler enerjik olarak uygulanmalıdır.
Hemodiyaliz Amaçlı Açılan A-v Fistüllerde Proksimal Distal Başarı Oranı Karşılaştırılması
(2006) Kotan, M. Çetin; Çiftçi, Ali; Başer, Murat; Sayarlioglu, Hayriye; Doğan, Ekrem; Erkoç, Reha
Amaç: Hemodiyaliz hastalarında yaşam beklentisi ve hayat kalitesi uygun bir damar yolu seçimi ile yeterli diyalize bağlıdır. Damar yolu yetersizliği hemodiyaliz hastalarında önemli bir problemdir. Bu konuda gelişen komplikasyonlar önemli morbidite nedenidir. Çalışmamızda kronik böbrek yetmezlikli hastalarda açılan arteriovenöz (A-V) fistüllerin, yerlerini de göz önüne alarak, erken ve geç dönemde açık kalma oranlarını ve cerrahi sonuçları değerlendirmeyi amaçladık. Method: Çalışmada, ocak 1997- aralık 2004 yılları arasında 114 kronik böbrek yetmezliği vakasına damar yolu amaçlı açılan arteriovenöz fistüller değerlendirildi. Operasyon için hastanın dominant olmayan kolu seçildi. Hastaların 63'ü erkek (% 55.3), 51'i kadındı (%44.7). Ortalama yaş 45.5±14.4 yıl idi. Bulgular: Açılan fistüllerin 39(%.29.5)'u radiosefalik, 86(%65.2)'sı brakiosefalik, 7(%5.3)'si brakiobazilik A-V fistüllerdi.Tüm vakalarda erken başarısızlık 18(%13.63) olguda, geç dönemde başarısızlık ise 8(%6.06) olguda gözlendi. Erken başarısızlık distaldeki fistüllerde (%23.07) proksimaldeki fistüllerden (%9.67) istatistiksel anlamlı olarak daha yüksek bulunmuştur (p<0.05). Geç dönemde ise proksimal ve distal başarısızlık oranları arasında istatistiksel fark yoktu (p>0.05). Açılan fistüllerin 31(%23.48)'inde komplikasyon gelişti. Sonuç: Ekstremite distaline açılan arterio venöz fistüllerde proksimale açılanlara oranla başarı oranları daha düşüktür. Brakial bölgeyi sonraki dönemlerde kullanılmak üzere korumak için distal uygulamalar ilk seçenek olarak tercih edilmelidir.
Homocysteine Levels and Lipid Profile in Hemodialysis Patients
(Ortadogu Ad Pres & Publ Co, 2007) Dulger, Haluk; Gur, Tugba; Sayarlioglu, Hayriye; Sekeroglu, Ramazan; Erkoc, Reha; Begenik, Hueseyin
Objective: The aim of this study was to investigate the levels of homocysteine and lipid profiles in patients included in hemodialysis programs for chronic renal failure (CRF). Material and Methods: The patients were divided into 2 groups and each group consisted of 30 patients, leading to a total of 60 patients. On the other hand, 20 healthy people comprised the control group. The first group (nontreated CRF) included new patients without a previous history of dialysis or any medical treatment; the second group (treated CRF) included patients who have received medical treatment [vitamin 13,2 (1 mg/month) and folic acid (15 mg/week)] and dialysis for at least the last 5 years. Serum total homocysteine, vitamin B-12, folic acid, creatinine, triglyceride, total cholesterol, HDL, LDL, VLDL, cholesterol levels were measured in all patients and the control group. Results: Levels of homocysteine were high in group I and group 2 patients (respectively p < 0.01, p < 0.05), whereas serum HDL cholesterol levels in group 2 were low compared to those in the control group (p < 0.01). In addition, a negative correlation was observed between homocysteine and folic acid levels in group 2 patients (r= -0.48, p < 0.01). Conclusion: The results of this study showed that homocysteine levels in CRF increased and this increase was lower in group 2 patients. Administration of folic acid reduced the levels of homocycstein. Thus, we Suggest that folic acid may be a significant factor to prevent the progression of chronic renal failure.
Internal Jugular Vein Thrombosis Two Different Etiologies
(Modestum Ltd, 2005) Erkoc, Reha; Uzun, Kursat; Yuca, Koksal; Etlik, Omer; Dogan, Ekrem; Sayarlioglu, Hayriye; Cankaya, Hakan
Internal Jugular vein (IJV) thrombosis is a rare entity. It is usually secondary to various etiologies such as catheter, malignancy, trauma, infection and hypercoagulable status. Associated malignancies, either known or occult, are also uncommon and not well documented in the etiology of IJV thrombosis. We reported IJV thrombosis with two different pathologies i.e. malignacy and congestive heart failure. The diagnosis of IJV thrombosis was established with Doppler ultrasound and CT scan. These patients were treated low-molecular-weight heparin and oral anticoagulation. Early diagnosis and appropriate management is important to prevent potentially fatal complications from internal jugular vein thrombosis.
Lymphocyte Subtype and Immunglobulins Levels in Hcv Positive Hemodialysis Pateints
(Modestum Ltd, 2012) Sayarlioglu, Hayriye; Erkoc, Reha; Dogan, Ekrem; Soyoral, Yasemin; Oner, Ahmet Faik
Epidemiological studies indicate that in chronic HD patients, bacterial and viral infection rank second place in mortality and morbidity, behind cardiovascular disease. Chronic hepatitis C virus (HCV) is very prevalent in some Hemodialysis (HD) centers. We have investigated lymphocyte subtype count and immunoglobulin levels in hemodialyzed patient with HCV. We studied 55 patients with end stage renal disease (ESRD) on chronic HD and 21 healty subjects. Patients group included 34 female and 21 male with mean age 46.5 +/- 16.1(18-77) years. Serum concentrations of IgG, IgM, IgA, CD4, CD8, CD19, CD16-56 lymphocytes were measured. Kt/V values were calculated according to DOQI guideline. Lymphocyte and lymphocyte subgroups values of HD patients were significant lower than healty persons. IgG, IgM and ALT levels of HCV positive HD patients compared with significant higher than HCV negative HD patients. CD4/CD8 ratios within groups were no differences. Lymphocyte subtype count of between HCV positive and HCV negative HD patients was no differences. IgG and IgM levels of HCV positive HD patients were higher than HCV negative HD patients. High Ig levels were also associated with ALT levels
Nutritional Status and Immune Functions in Maintenance Hemodialysis Patients
(Hindawi Ltd, 2006) Sayarlioglu, Hayriye; Erkoc, Reha; Demir, Cengiz; Dogan, Ekrem; Sayarlioglu, Mehmet; Oner, Ahmet Faik; Dilek, Imdat
Epidemiological studies suggest various kinds of immune dysregulation in hemodialysis (HD) patients. The aim of this study was to investigate the relationship between immune functions and nutritional status of HD patients. We studied 54 patients with ESRD on chronic HD, included 34 females and 20 males with mean age 46.6 +/- 16.3 (18-77) years. We measured the height and dry weight of all patients. The BMI was calculated by dividing weight (kg) by height squared (m(2)). In all patients serum urea, creatinine, albumin, iron, cholesterol, triglyceride, CRP, IgG, IgM, IgA, CD4, CD8, CD19, CD16-56 lymphocytes were measured. Kt/V values were calculated according to DOQI guideline. In this study, a positive correlation between albumin, cholesterol, and triglyceride levels as nutritional parameters and immune functions in terms of total and subtype lymphocyte counts was observed. Further prospective studies are needed to determine the clinical importance of this finding and the appropriate means of measurement and effects of nutrition on immune function in hemodialysis patients. Copyright (c) 2006 Hayriye Sayarlioglu et al.
Prevalence and Risk Factors of Restless Leg Syndrome in a Single Hemodialysis Unit
(Tubitak Scientific & Technological Research Council Turkey, 2010) Soyoral, Yasemin; Sayarlioglu, Hayriye; Tuncel, Deniz; Sahin, Murat; Dogan, Ekrem; Erkoc, Reha
Aim: Restless legs syndrome (RLS) is characterized by symptoms of spontaneous, continuous leg movements associated with unpleasant paresthesias. RLS is common among dialysis patients, with a reported incidence of 6 6 to 6 8 percent. This study is an attempt to find out the prevalence of RLS in our hemodialysis patients. We compared several demographic and clinical characteristics of RLS patients identified by the International Restless Legs Syndrome Study Group (IRLSSG) criteria with those of individuals without RLS. Materials and methods: We studied 76 patients with end-stage renal disease (ESRD) on hemodialysis (34 females and 42 males, mean age 52 28 +/- 18.13, range 18-83 years) RLS patients' diagnoses were confirmed using the IRLSSG criteria. RLS is diagnosed when a patient answered positively to all of the 4 questions. Hemoglobin, ferritin, iron, iron binding capacity, PTH, and Kt/V ratio values were measured Results: We found an RLS frequency of 14 5% in our sample. There was no significant difference in terms of serum iron, terrain, creatinine, iPTH, hemoglobin, and Kt/V between groups of hemodialysis patients with and without RLS (P = 0.89, 0 87, and 0 37, respectively) Conclusion: The 14 5% prevalence of RLS in hemodialysis patients was lower than that has been reported previously The variability in RLS prevalence rates among hemodialysis patients may result from some racial, regional, socioeconomic, or ethnic differences These findings need to be confirmed in larger studies
Profile of Behcet's Disease at Van and Vicinity
(Modestum Ltd, 2005) Calka, Omer; Akdeniz, Necmettin; Metin, Ahmet; Sayarlioglu, Hayriye
Aim: Behcet's disease is a chronic, progressive disease with an unknown etiology and involves many organs and systems. Although the disease can be encountered at different regions on earth, prevalence and clinical findings of the disease may demonstrate differences due to local and geographical specifications. Methods: We report epidemiological and clinical characteristics of 65 patients with Behcet disease during four years in Van and vicinity. Results: The patients, mean age was 32.8 years (16-72 years) and the disease was more common between 21 and 40 years. The sex ratio was 1.4 (38 men - 27 women). Frequencies of the clinical features were as follows: oral aphthae (100%), genital ulcer (84.6%), cutaneous findings (61.1%), ocular (40%) neurological (27.6%), articular (52.3%), vascular (16.9%), gastrointestinal (27.6%), epididymitis (3%) and positive pathergy test (46.1%). Conclusion: We thought that, this first description of data about BD in Van and vicinity might be helpful for researchers.
Rakımın İdrarda Protein Atılımı Üzerine Etkisi
(2005) Bayraktaroğlu, Taner; Doğan, Ekrem; Koçak, Gülay; Koçak, Erdem; Külah, Eyüp; Erkoç, Reha; Sayarlioglu, Hayriye
Amaç: İdrar protein miktarı 24 saatlik idrar toplanarak ölçülür ve günlük 150 mg'a kadar olan değerler normal kabul edilir. Normal populasyonda deniz seviyesinden yükseğe çıkıldıkça proteinürinin normal seviyelerinin değişip değişmediği bilinmemektedir. Çalışmamızda 1727 m rakımda yaşayan sigara içmeyen sağlıklı insanlardaki proteinüri seviyelerini deniz seviyesindeki sağlıklı populasyonla karşılaştırdık. Yöntem: Denizden 1727 m yüksek bir yerleşim yeri olan Van ile deniz seviyesindeki Zonguldak'ta yaşayan sağlıklı ve sigara içmeyen, Van'dan 35 (21 kadın, 14 erkek/yaş aralığı: 16-74, yaş ort.: 36,7±15 yıl) Zonguldak'tan-28 (15 kadın,13 erkek, yaş aralığı:22-62, yaş ort.:. 42,1±12,1 yıl) gönüllü katılımcı çalışmaya alindi, Her iki grup arasında yaş, cins,hemoglobin ve ürik asit düzeylerinde istatistiksel açıdan fark yoktu. Van'da ölçülen idrar protein ortalama 60±29,8 (10-13Q jn'g/dl), Zonguldak'ta 64,7±29,8 (10-130,5 mg/dl) idi (p=0,53), Sonuç: Çalışmamızdaki vaka grubunda proteinüri açısından her iki grup arasında anlamlı fark bulunamadı.