Browsing by Author "Sayhan, H."
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Letter Comment On: Does Sugammadex Decrease the Severity of Agitation and Complications in Pediatric Patients Undergoing Adenotonsillectomy(Saudi Arabian Armed Forces Hospital, 2019) Kim, Y.H.; Korkmaz, M.O.; Sayhan, H.; Guven, M.Article The Correlation Between Red Blood Cell Distribution Width Levels With the Severity of Obstructive Sleep Apnea and Carotid Intima Media Thickness(International Scientific Literature Inc., 2014) Gunbatar, H.; Sertogullarindan, B.; Ekin, S.; Akdag, S.; Arisoy, A.; Sayhan, H.Background: Obstructive sleep apnea syndrome (OSAS) is characterized by repetitive collapse of the upper airway during sleep. Red blood cell distribution width (RDW) increases platelet activation and has been reported as an independent predictor of adverse outcomes in the general population and is believed to be associated with cardiovascular morbidity and mortality. We evaluated RDW, mean platelet volume (MPV), and platelet distribution width (PDW) as a severity index in OSAS and the relationship between carotid intima media thickness and pulmonary hypertension.; Material/Methods: The study population consisted of 99 patients who were admitted to the sleep laboratory. Based on the apneahypopnea index, patients were grouped into 3 OSAS severity categories. Morning blood samples were withdrawn from patients after a 12-hour fasting period. MPV, PDW, and RDW were measured in a blood sample. Bilateral common carotid arteries of the patients were scanned.; Results: Ninety-nine patients – 73 with OSAS and 26 simple snoring control cases – were included. Mean values of MPV, PDW, and RDW were similar in patients compared to simple snoring subjects in the control group (p=0.162, p=0.656, p=0.091). RDW showed an inverse correlation with mean desaturation and lowest desaturation (p<0.01). Body mass index, apnea-hypopnea index, pulmonary artery pressure, and desaturation time under 90% were positively correlated with RDW (p<0.05). MPV, PDW, and carotid intima media thickness had no correlation with any other parameters.; Conclusions: The study showed a positive relationship between RDW and the apnea-hypopnea index and systolic pulmonary hypertension in patients with OSAS. © Med Sci Monit, 2014.Article Does Sugammadex Decrease the Severity of Agitation and Complications in Pediatric Patients Undergoing Adenotonsillectomy(Saudi Arabian Armed Forces Hospital, 2019) Korkmaz, M.O.; Sayhan, H.; Guven, M.Objectives: To evaluate the effectiveness of sugammadex in reducing or eliminating postoperative agitation levels, early respiratory complications and nausea/vomiting in children undergoing adenotonsillectomy. Methods: A total of 70 patients (age range: 5-13 years) who underwent an adenotonsillectomy in the Otolaryngology Clinic, Sakarya University, Sakarya, Turkey between May 2015 and September 2017 were included in the study. The patients were randomized into a sugammadex group (Group S) and a neostigmine + atropine (Group N); each group contained 35 patients. Time to extubation, postoperative agitation levels, and early postoperative complications were evaluated and recorded. Data from both groups were statistically evaluated and compared. Results: The time to extubation was significantly shorter in Group S than Group N (p<0.05). Agitation scores during recovery were significantly lower in Group S than Group N (p<0.05). More complications were observed in Group N than in Group S; the number of patients seen coughing and experiencing nausea/vomiting in Group S was statistically significantly lower (p<0.05). Conclusion: This study demonstrated that the use of sugammadex results in less time to recovery and less agitation in comparison to conventional administration of neostigmine + atropine in the reversal of neuromuscular blocking after adenotonsillectomy. © 2019 Saudi Arabian Armed Forces Hospital. All rights reserved.