Browsing by Author "Sayin, R."

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Acute Motor Axonal Neuropathy Cases in Van Region
(Comenius Univ, 2011) Sayin, R.; Tombul, T.; Gulec, T. C.; Anlar, O.; Akbayram, S.; Caksen, H.
Acute motor axonal neuropathy (AMAN) is a form of Guillain Barre Syndrome (GBS) seen in summer months in Northern China to cause epidemics. This form of the disease, which is also sporadically observed in other countries, constitutes less than 5 % of GBS in Western countries. It usually develops with motor findings. No sensory findings are observed. In some of the cases, the severe impairments in tissues improve however slowly and inadequately. In the motor conduction studies of cases with AMAN, motor action potential values are lowered. On needle electromyography (EMG), motor unit potential (MUP) activity is diminished with spontaneous denervation findings. Investigations were conducted on nerve conduction of patients with GBS aged from 1 to 77 years. AMAN was detected in 25 of these patients. In our investigation, AMAN as a GBS variant was detected in 39.7 % of the patients. The conduction velocities of motor nerves were in normal ranges whereas combined muscle action potentials were significantly lower. No F response could be obtained. Although AMAN is a rare variant of GBS and shows different clinical courses, it has been brought under intense scrutiny since there is high prevalence of acute inflammatory neuropathies in our region (Tab. 1, Ref. 7). Full Text in free PDF www.bmj.sk.
A Case With Multiple Sclerosis and Familial Mediterranean Fever
(Medecine Et Hygiene, 2011) Sayin, R.; Alpayci, M.; Soyoral, Y. Usul
Clinical and Magnetic Resonance Imaging Findings of Siblings From a Turkish Family With Mother Diagnosed as Multiple Sclerosis: Case Report
(Sage Publications Ltd, 2006) Anlar, O.; Sayin, R.; Kayan, M.; Tombul, T.; Unal, O.
Clinical Presentation and the Efficacy of Antiepileptic Therapy in the Patients With Partial and Generalized Epilepsy
(2011) Sayin, R.; Tombul, T.; Anlar, O.; Caksen, H.
Epilepsy is an abnormal recurrent disease, resulting from various disorders of central nervous system. In this study, we aimed to compare the patients in terms of therapeutic efficiency. We enrolled a total of 106 patients in the study and of them, 45 were male and 61 were female, aged between 2 to 52 years. Of these patients, 69 (65%) had partial and 37 (35%) had generalized seizures. Seventy three patients were being treated with monotherapy and 33 patients were being treated with polytherapy. The number of the patients that were taking monotherapy was higher in the pediatric group (age, 0 to 16) compared to adult group (age, above 16). In the study, we tried to express the importance of monotherapy in the pediatric patients, the higher number of the pathologies that can be detected using an imaging method in the patients with partial epilepsy compared to that of generalized epilepsy, and the most frequent occurrence of therapeutic resistance in the partial epilepsies, ©2011 Academic Journals.
Congenital Myasthenic Syndrome: a Case Report
(Medecine Et Hygiene, 2011) Ceylan, A.; Tuncer, O.; Sayin, R.; Peker, E.; Caksen, H.; Sari, S.
Congenital myasthenic syndrome: a case report: Congenital myasthenic syndromes (CMS) are diseases of the neuromuscular junction. They usually belong to the disease groups that begin in the infantile or childhood period and carry genetic characteristics. The following is important in establishing the diagnosis of this disease: clinical findings, electromyography, genetic tests, determination of serum acetylcholine receptor antibodies. Acetylcholine esterase inhibitor drugs are used in treatment of CMS. A seven-month old male patient was brought to our department with the complaints of difficult breathing, falling of the eyelids and swallowing difficulty. With clinical and laboratory findings, he was diagnosed with congenital myasthenia and treatment was started. CMS should be suspected in patients with no pathological findings on the physical examination, and normal chest X-rays.
Eclampsia With Neurological Complications: a Five-Year Experience of a Tertiary Centre
(I R O G Canada, inc, 2013) Kurdoglu, Z.; Ay, G.; Sayin, R.; Kurdoglu, M.; Kamaci, M.
Purpose: The neurological signs and symptoms in 107 pregnant women with eclampsia in the last five years at the Department of Obstetrics and Gynecology at the Yuzuncu Yil University School of Medicine are presented. Materials and Methods: The medical records of 107 pregnant women with eclampsia in the Clinic of Obstetrics and Gynecology at the Yuzuncu Yil University consulted with neurology clinic from September 2005 to December 2010, were evaluated. Results: The most common symptoms of the patients were seizure, headache, and seeing spots of light. Although neurologic examination was normal in 81 patients, 26 had pathological signs. The most common neurologic pathologic signs determined were alterations in consciousness. Conclusion: In eclamptic patients, brain scanning might reveal pathological results in spite of normal neurological examination. With neurological examination and brain scanning, it may be possible to diagnose and treat severe complications that may otherwise result in maternal mortality.
Posterior Reversible Encephalopathy Syndrome in Eclamptic Patients: Five Years Experience of a Tertiary Center
(Wiley-blackwell, 2014) Kurdoglu, Z.; Sayin, R.; Cetin, O.; Dirik, D.; Karaagac, N.
Sleep Quality, Depression and Anxiety in Carpal Tunnel Syndrome
(2008) Tekeoǧlu, I.; Gülcü, E.; Sayin, R.; Beşiroǧlu, L.; Yazmalar, L.
Objective: The purpose of this study was to examine the sleep disorders, anxiety and depression caused by CTS in patients, and whether electrodiagnostic study findings were associated with the severity of symptoms of sleep quality, anxiety and depression in patients. Materials and Methods: Using a case-control methodology, 87 electrophysiologically confirmed CTS patients with a mean age of 45±13 (27-62) years (86.9% women, n=73) and 50 controls with a mean age of 40±9.2 (21-56) years (54% women, n=27) were examined. Clinical neurological examinations of CTS patients and validated Turkish version of self-reported Sleep Quality Index, Beck Depression Scale and Beck Anxiety Scale were employed. Results: The majority of patients in the CTS group had worse symptoms of depression and anxiety, compared with the control group (p<0.05). The severity of CTS was not significantly associated with right and left hand utilization and the severity of symptoms of self-reported sleep quality, anxiety and depression scales. There were no statistically significant relationships between the electrodiagnostic findings and the patient functional status and symptom severity. Conclusion: Electrodiagnostic findings and patient CTS-related symptoms and sleep, anxiety and depression appear to be independent measures. Clinicians and researchers interested in CTS outcomes need to assess both. While depression and anxiety levels are found to be high in CTS, sleep-quality is relatively low. However, knowing that there is no correlation between the intensity of the illness and the number of symptoms with those variables, leads us to consider that the severity of the illness is evaluated on the self reports of patients. For this reason, physical impacts of the illness should also be evaluated as subjective.
Thrombocytopenia Due To the Use of Rifampicin in Brucellosis
(2012) Demir, C.; Sayin, R.; Soyoral, Y.; Karahocagil, M.K.
Thrombocytopenia may develop after drug therapy and is a life-threatening condition. Thrombocytopenia may also occur after high-dose use of rifampicin which is an antibiotic. Here, we report five cases of thrombocytopenia developing after the use of rifampicin for the treatment of brucellosis. Four cases had experienced diffuse petechiae and ecchymosis with severe thrombocytopenia. The other patient had a complicated thrombocytopenia with intracerebral hemorrhage. As a result, the usage of rifampicin in the treatment of brucellosis could lead to systemic or central complications.