Browsing by Author "Sayir, Fuat"

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A 3-Cm Single-Port Video-Assisted Thoracoscopic Lobectomy for Lung Cancer
(Lippincott Williams & Wilkins, 2015) Ocakcioglu, Ilhan; Sayir, Fuat; Dinc, Mustafa
Video-assisted thoracoscopic surgery is advantageous over traditional surgical practices, because of a faster postoperative recovery period, less pain, and a shorter hospital length of stay. There is no single standard technique in the video-assisted thoracoscopic surgery approach. Although these minimally invasive resections are habitually performed through 3-port or 4-port incision, we performed a left lower lobectomy in a 54-year-old male patient for lung cancer, through a 3-cm single-port incision.
Are Serum Mac 2-Binding Protein Levels Elevated in Esophageal Cancer? a Control Study of Esophageal Squamous Cell Carcinoma Patients
(Hindawi Ltd, 2018) Cobanoglu, Ufuk; Mergan, Duygu; Dulger, Ahmet Cumhur; Celik, Sebahattin; Kemik, Ozgur; Sayir, Fuat
Objective. Elevated serum Mac 2-binding protein (M2BP) levels have been observed in some cancers. As far as we know, its importance has not been investigated in esophageal squamous cell carcinoma (ESCC). The investigated problem of this study was to evaluate whether there was a difference between ESCC patients and the control group in terms of M2BP. Also, we evaluated the diagnostic performance of serum M2BP alone or in combination with the CEA for patients with ESCC. Material and Methods. Blood serum samples were collected from 50 healthy donors and 150 patients with ESCC. M2BP levels of all 200 samples were quantified by ELISA (enzyme-linked immunosorbent assay). Patients who had been diagnosed with ESCC and did not have any other malignancies were enrolled to study. Results. The two groups did not significantly differ in terms of age (p > 0 05). In the control group, the mean serum M2BP level was 14.97 coproduct 3.46 ng/mL. The mean serum M2BP level of the ESCC patients was 176.65 +/- 22.14 ng/mL. The serum M2BP level was significantly higher in patients with ESCC than in the control group (p < 0 001). Gender was also comparable in both groups (p = 0 695). Conclusions. Our analysis demonstrated that this marker may be associated with the mechanism of the disease. Despite that serum M2BP is not a specific marker for ESCC, it can be used as an adjuvant biomarker for the diagnosis of ESCC.
Borchardt Triade: a Symptom of Acute Gastric Volvulus
(derman Medical Publ, 2014) Bilici, Salim; Goksu, Mehmet; Melek, Mehmet; Sayir, Fuat; Simsek, Metin
Gastric volvulus, especially cases with an acute onset, may result strangulation, perforation, peritonitis, shock and death. The disease is rarely seen in children, but early diagnosis and treatment is essential due to its life-threatening potential. In patients with acute gastric volvulus, the clinical Borchardt triade may be observed, which is characterized by acute severe pain and distension in the upper abdomen or lower thoracic region, retching and the inability to pass a nasogastric tube. In this article, We aimed to emphasize the Borchardt's triad by presenting a pediatric case who was diagnosed with Borchardt's triad and who had acute mesenteric axial gastric volvulus which diaphragmatic hernia and mobile (wandering) spleen were accompanied.
Chest Traumas Due To Bicycle Accident in Childhood
(derman Medical Publ, 2011) Cobanoglu, Ufuk; Melek, Mehmet; Sayir, Fuat; Mergan, Duygu
Aim Childhood injuries are the leading cause of death in children and result in significant healthcare utilization. Trauma is the second most common cause of mortality in children aged 1-4 years and leading cause of death in children older than 4 years. Thoracic injury is the second most leading cause of death in traumatized children. Multisystemic injury is found in more than 50% of children with thoracic injuries most of which are secondary to blunt traumas. We planned this study to evaluate thorax trauma cases secondary to bicycle driving in childhood and to draw attention to the importance of the regulation of traffic rules, the education of bicycle drivers. Material and Methods A retrospective evaluation was performed in 17 pediatric patients admitted to the Department of Thoracic Surgery during 2006-2010 with a diagnosis of chest trauma due to bicycle driving. For every patient, a pediatric trauma score (PTS) was calculated. Descriptive statistics were performed for PTS. Results Eleven (64.70%) cases were injured due to the tricycle accidents and six cases 6 (35.29%) were injured due to the two-wheeled bicycle accidents. The most frequent thoracic pathologies included pulmonary contusion (41.2%) and chest wall contusion (29.41%). Extrathoracic injuries were seen in 35.29%, the extremities (17.64%) and abdomino pelvic (11.76%) being the most commonly involved. Treatment consisted of symptomatic treatment in 12 patients (70.58%), tube thoracostomy in 2 patients (11.76%), and thoracotomy in 1 patient (5.9%). The morbidity was seen in 3 patients (17.64%). The mortality rate was 5.9% (n:1). The mean PTS of the cases who had additional system injuries were significantly worse than the cases who had isolated chest traumas. Conclusions The pediatric thorax has a greater cartilage content and incomplete ossification of the ribs. Due to the pliability of the pediatric rib cage and mediastinal mobility, significant intrathoracic injury may exist in the absence of external signs of trauma. Pulmonary contusion and pneumothorax are frequently present without rib fractures. Pulmonary contusion, pneumothorax, and rib fractures are the most common injuries. In order to prevent bicycle accidents; bicycle drivers should have specific education, helmet use must become widespread and special traffic regulations have to be settled. Increasing the education level if family will contribute to the prevention of childhood trauma.
Clinical Analysis of Pneumonectomy for Destroyed Lung: a Retrospective Study of 32 Patients
(Springer Japan Kk, 2019) Sayir, Fuat; Ocakcioglu, Ilhan; Sehitogullari, Abidin; Cobanoglu, Ufuk
ObjectiveDestroyed lung is whole lung destruction secondary to chronic or recurrent lung infections. This clinical condition can result in irreversible changes in the lung parenchyma. In this study, we aimed to evaluate patients undergoing pneumonectomy with a diagnosis of lung destruction in terms of surgical technique, post-operative morbidity and mortality, and long-term outcomes.MethodsA total of 32 patients that underwent pneumonectomy due to a destroyed lung between 2005 and 2017 were retrospectively reviewed. Age, gender, presenting symptoms, etiologies, localization of the destruction, pre-operative medical history, pre- and post-operative respiratory function tests, intraoperative complications and bleeding volume, morbidity and mortality, length of hospital stay, and long-term follow-up outcomes were reviewed for each patient.ResultsThe study included 32 patients with a mean age of 31.710.8years. All the patients presented with persistent cough, whereas sputum production was presented by 25, hemoptysis by 18, and chest pain by 11 patients. The underlying primary diseases included nonspecific bronchiectasis in 20 (62.5%), tuberculosis in 9 (28.1%), left pulmonary hypoplasia accompanied by Bochdalek hernia in 2 (6.2%), and aspiration of a foreign body lodged in the left main bronchus in 1 (3.1%) patient. Mean operative time was 220.6 +/- 40.2min and mean perioperative bleeding was 450.9 +/- 225.7ml. Post-operative complications occurred in 14.2% of the patients, most commonly including atelectasis associated with stasis of secretions and wound site infection. Mean post-operative hospital stay was 11.8 +/- 2.8days and mean follow-up period was 35.5 +/- 28.3months. A significant clinical improvement was observed in 81.2% of the patients post-operatively.Conclusions Favorable long-term outcomes were obtained in our patients through careful patient selection and appropriate pre-operative work-up and surgical technique.
Clinical Profile of Thorax and Lung Injuries Associated With the 2011 Van Earthquake in Turkey
(Modestum Ltd, 2013) Sehitogullari, Abidin; Kahraman, Ali; Sayir, Fuat; Akin, Oral; Sevilgen, Gokcen; Cobanoglu, Ufuk; Aktas, Serdar
The 7.2 and 5.6 magnitude earthquake that struck Turkey on October 23 and November 9, 2011, was one of the deadliest earthquakes in recent decade. Our aim is to determine the clinical profile of crush thoracic traumas resulting from the massive Van earthquake. A retrospective review was undertaken of 39 intervention for chest traumas. Sex distrubition was 21 female and 18 male patients. Thoracic cage, pulmonary parenchyma, and pleura traumas were included in the study. Among the total of 425 hospitalized patients, 39 (9.1%) were thorax and lung injuries. Pneumothorax and rib fractures were the two most frequent pathologies. There were pneumothorax or hemothorax in 31 (79%) patients, bronch ruptures in 2 (5.1%) patients, diaphragmatic ruptures in 2 (5.1%) patients, flail chest in 2 (5.1%) patients and sternal fracture was detected in 2 (5.1%) patients. Totally, 76 ribs fractures were found in 27 (69%) patients, There were 36 (92%) patients with pulmonary parenchymal injuries and 31 (79%) with pleural injuries. Thoracotomy was performed in 4 (10%) patients, while 37 (95%) patients underwent tube thoracostomy. Carinal reconstruction was performed in a patient with bronchus and trachea injuries. Four patients (10%) with severe trauma developed Acute Respiratory Distres Syndrome (ARDS) and two of them died because of developing ARDS. After the patients are admitted to the hospital, we should use an individualized treatment according to the patients recent clinical history and examination. At the same time, traumatic chest injury should be considered in planning the medical response strategies.
Comparison of the Methods of Fibrinolysis by Tube Thoracostomy and Thoracoscopic Decortication in Children With Stage Ii and Iii Empyema: a Prospective Randomized Study
(Pagepress Publ, 2011) Cobanoglu, Ufuk; Sayir, Fuat; Bilici, Salim; Melek, Mehmet
Today, in spite of the developments in imaging methods and antibiotherapy childhood pleural empyema is a prominent cause of morbidity and mortality. In recent years it has been shown that there has been an increase in the frequency of pleural empyema in children, and antibiotic resistance in microorganisms causing pleural empyema has made treatment difficult. Despite the many studies investigating thoracoscopic debridement and fibrinolytic treatment separately in the management of this disease, there is are not enough studies comparing these two treatments. The aim of this study was to prospectively compare the efficacy of two different treatment methods in stage II and III empyema cases and to present a perspective for treatment options. We excluded from the study cases with: i) thoracoscopic intervention and fibrinolytic agent were contraindicated; ii) immunosup pression or additional infection focus; iii) concomitant diseases, those with bronchopleural fistula diagnosed radiologically, and Stage I cases. This gave a total of 54 cases: 23 (42.6%) in stage II, and 31 (574%) cases in stage III. These patients were randomized into two groups of 27 cases each for debridement or fibrinolytic agent application by video-assisted thoracoscopic decortication (VATS). The continuity of symptoms after the operation, duration of thoracic tube in situ, and the length of hospital stay, in the VATS group were of significantly, shorter duration than in the streptokinase applications (P=0.0001). In 19 of 27 cases (70.37%) in which fibrinolytic treatment was applied and in 21 cases of 27 (77.77%) in which VATS was applied, the lung was fully expanded and the procedure was considered successful. There was no significant difference with respect to success rates between the two groups (P-0.533). The complication rate in our cases was 12.96% and no mortality was observed. Similar success rates in thoracoscopic drainage and enzymatic debridement, and the low cost of enzymatic drainage both served to highlight intrapleural streptokinase treatment as a reliable method in reducing the need for surgery in complicated empyema.
Diagnostic Dilemma in Hydatid Cysts: Tumor-Mimicking Hydatid Cysts
(Aves, 2015) Cobanoglu, Ufuk; Asker, Selvi; Mergan, Duygu; Sayir, Fuat; Bilici, Salim; Melek, Mehmet
OBJECTIVES: Hydatid cysts are sometimes confused with different pathologies, and problems arise in their diagnosis and treatment. In this study, cases that are followed up with a diagnosis of lung malignancy and that are detected to have hydatid cysts were retrospectively examined. MATERIAL AND METHODS: Seven patients with hydatid cysts whose clinical and radiological features were consistent with lung malignancy were retrospectively examined between 2010 and 2014 regarding sex, age, symptoms, diagnostic methods, surgical procedures performed, and postoperative complications. In the diagnosis of the patients, radiological diagnostic methods such as chest radiography, thoracic computed tomography (TCT), and positron emission tomography+computed tomography (PET-CT) as well as invasive diagnostic methods such as bronchoscopy, fine-needle aspiration biopsy, thoracentesis, and video-assisted thoracoscopic surgery were used. RESULTS: The average diameter of the lesions was determined as 4.14 +/- 1.57 cm in TCT. Maximum standardized uptake value (SUV max) was measured as 8.77 +/- 3.41 (5.4-15.1) in the PET-CT analysis. Bronchoscopy, fine-needle aspiration biopsy, and thoracentesis yielded no results. Definitive diagnosis was established by performing thoracotomy and video-assisted thoracoscopic surgery. CONCLUSION: Pulmonary hydatid cysts can appear as malignant diseases such as lung cancer as well as infectious pathologies such as tuberculosis or benign pathologies. Radiologically, it should be kept in mind that pulmonary hydatid cysts can mimic many pulmonary pathologies, particularly malignancies. Necessary examinations towards its differential diagnosis must be performed in the preoperative period.
Diaphragmatic Herniation Diagnosed at a Late Stage: an Evaluation of Eight Cases
(Baycinar Medical Publ-baycinar Tibbi Yayincilik, 2012) Sayir, Fuat; Cobanoglu, Ufuk; Bilici, Salim; Melek, Mehmet; Mergan, Duygu
Background: In this study, we aimed to analyze patients with diaphragmatic hernias who had specific clinical features and interesting clinical, radiologic presentations, and had operated following late diagnosis. Methods: A total of eight diaphragmatic hernia cases, of whom three were adults and five were children (4 males, 4 females; mean age 12.4 +/- 24 years; range 9 months to 28 years), who were diagnosed in the late period and who were operated on in our clinic between January 2006 and August 2010 were evaluated retrospectively. In all patients, primary repair of the diaphragm was performed following laparotomy and thoracotomy. Results: The children were diagnosed following the neonatal period. Three patients were diagnosed in adulthood. Five patients had right-sided congenital Morgagni hernias, one patient had a hiatal hernia, and two patients had left-sided Bochdalek hernia. All patients were discharged between the 5th and 19th postoperative days. The average duration of hospital stay was 9.8 days (range 7 to 23 days). The follow-up time were between six months and two years, and no significant respiratory and gastrointestinal complaints were recorded. No morbidity was detected in three cases with Morgagni hernia. Conclusion: Congenital diaphragmatic hernias are pathologies which are seen in the neonatal period, and the diagnosis of these hernias can be difficult after this period. Mortality and morbidity rates are low in cases who are followed and treated in clinics by dedicated thoracic surgeon.
Effect of Crush and Axotomy of Phrenic Nerves on Oxidative Stress in Diaphragm Muscle of Rats
(Wiley, 2012) Sayir, Fuat; Kavak, Servet; Meral, Ismail; Demir, Halit; Cengiz, Nurettin; Cobanoglu, Ufuk
Introduction: In this study we investigated the effect of crush and axotomy of phrenic nerves on oxidative stress and antioxidant enzyme activities in rat diaphragm muscle. Methods: The animals in the first group were not crushed or axotomized and served as controls. Phrenic nerves of the rats in the second and third groups were crushed or axotomized in the diaphragm muscle. Results: The malondialdehyde level increased in diaphragm muscles after both crush and axotomy. The antioxidant enzymes, such as superoxide dismutase, glutathione peroxidase, carbonic anhydrase, and catalase, decreased in diaphragm muscles after both crush and axotomy. Conclusions: Crushing or axotomizing the phrenic nerves may produce oxidative stress in the diaphragm muscle of the rat by increasing lipid peroxidation and decreasing antioxidant enzyme activities. Muscle Nerve, 2012
The Effect of Diaphragmatic Plication on Pulmonary Function Test, Dyspnea Score and Arterial Blood Gases: Analysis 11 Patients With Diaphragmatic Elevation
(derman Medical Publ, 2011) Cobanoglu, Ufuk; Sayir, Fuat; Mergan, Duygu; Toktas, Osman
Aim Diaphragmatic evantration or paralysis in adults is associated with respiratory distress. In this study, we aimed to compare preoperative and postoperative pulmonary function tests, arterial blood gas analyses and dyspnea scores of the cases in whom plication had been performed for diaphragmatic elevation. Material and Methods Between January 2004 and March 2010 eleven adult patients who had undergone diaphragmatic plication due to diaphragmatic paralysis and eventration were analyzed. There were 7 (63.63%) men and 4 (36.37%) women aged 28-65 (mean 38 +/- 2.9). Diaphragmatic plication was performed. Pulmonary function test, dyspnea scores, and arterial blood gases in the preoperative and postoperative period were studied. Results Dyspnea was present in all of the cases and a decrease in both FVC, FEV1, FEV1/FVC values of pulmonary function test and partial pressure of oxygen in the arterial blood were observed. In chest x-ray and thorax computed tomography, it was detected that right or left diaphragm was elevated. Diaphragmatic paralysis was detected by fluoroscopy in 6 patients. Transthoracally, diaphragmatic plication was performed to the cases. There were no postoperative complications or deaths. In postoperative six and twelve months, significant improvements in the symptoms, the values of pulmonary function tests, partial pressure of oxygen in the arterial blood and dyspnea scores of the patients were observed. Conclusions Diaphragmatic plication is a safe and effective procedure for adult patients with dyspnea due to unilateral diaphragmatic elevation. Lung expansion is easily achieved by performing diaphragm plication.
Effects of Crush and Axotomy on Oxidative Stress and Some Trace Element Levels in Phrenic Nerve of Rats
(Pergamon-elsevier Science Ltd, 2013) Sayir, Fuat; Kavak, Servet; Meral, Ismail; Demir, Halit; Cengiz, Nurettin; Cobanoglu, Ufuk
This study was designed to investigate the effect of crush and axotomy on oxidative stress and some trace element levels in phrenic nerve of rats. Eighteen male Wistar-albino rats were divided randomly into three groups, each consisting of 6 rats. The animals in the first group were not crushed or axotomized and served as control. Phrenic nerves of the animals in the second and third groups were crushed and axotomized, respectively. Animals in all groups were sacrificed one week after the crush or axotomy, and degenerated phrenic nerves were harvested for the determination of tissue oxidative stress and trace element levels. Lipid peroxidation product malondialdehyde and antioxidant glutathione levels increased in both crushed and axotomized phrenic nerves. The activities of antioxidant enzymes such as superoxide dismutase, catalase and glutathione peroxidase were lower in crushed and axotomized phrenic nerves than in controls. The levels of Fe, Pb, Mn, Cd and Co increased, and Mg and Cu levels decreased in crushed phrenic nerves. The levels of Fe and Mg decreased, Pb and Co levels increased in axotomized phrenic nerves. It was concluded that crushing or axotomizing the phrenic nerves may produce oxidative stress by increasing lipid peroxidation and decresing antioxidant enzyme activities. It was also concluded that while crush to phrenic nerves causes accumulation of minerals, axotomizing phrenic nerves causes depletion of minerals in the tissues. (C) 2011 Elsevier Inc. All rights reserved.
The Effects of Phrenic Nerve Degeneration by Axotomy and Crush on the Electrical Activities of Diaphragm Muscles of Rats
(Humana Press inc, 2016) Alkis, Mehmet Esref; Kavak, Servet; Sayir, Fuat; Him, Aydin
The aim of this study was to investigate the effect of axotomy and crush-related degeneration on the electrical activities of diaphragm muscle strips of experimental rats. In the present study, twenty-one male Wistar-albino rats were used and divided into three groups. The animals in the first group were not crushed or axotomized and served as controls. Phrenic nerves of the rats in the second and third groups were crushed or axotomized in the diaphragm muscle. Resting membrane potential (RMP) was decreased significantly in both crush and axotomy of diaphragm muscle strips of experimental rats (p < 0.05). Depolarization time (T (DEP)) and half-repolarization (1/2 RT) time were significantly prolonged in crush and axotomy rats (p < 0.05). Crushing or axotomizing the phrenic nerves may produce electrical activities in the diaphragm muscle of the rat by depolarization time and half-repolarization time prolonged in crush and axotomy rats.
Effects of Shock Waves on Oxidative Stress and Some Trace Element Levels of Rat Liver and Diaphragm Muscles
(Wiley, 2012) Gecit, Ilhan; Kavak, Servet; Meral, Ismail; Gunes, Mustafa; Pirincci, Necip; Sayir, Fuat; Ceylan, Kadir
This study was designed to investigate whether the short-term extracorporeal shockwave lithotripsy (ESWL) exposure to kidney produces an oxidative stress and a change in some trace element levels in liver and diaphragm muscles of rats. Twelve male Wistar albino rats were divided randomly into two groups, each consisting of six rats. The animals in the first group did not receive any treatment and served as control group. The right-side kidneys of animals in group 2 were treated with two-thousand 18?kV shock waves while anesthetized with 50?mg kg-1 ketamine. The localization of the right kidney was achieved after contrast medium injection through a tail vein under fluoroscopy control. The animals were killed 72 h after the ESWL treatment, and liver and diaphragm muscles were harvested for the determination of tissue oxidative stress and trace element levels. Although the malondialdehyde level increased, superoxide dismutase and glutathione peroxidase enzyme activities decreased in the livers and diaphragm muscles of ESWL-treated rats. Although glutathione level increased in liver, it decreased in diaphragm muscles of ESWL-treated animals. Fe, Mg and Mn levels decreased, and Cu and Pb levels increased in the livers of ESWL-treated animals. Fe and Cu levels increased, and Mg, Pb, Mn and Zn levels decreased in the diaphragm muscles of ESWL-treated animals. It also causes a decrease or increase in many mineral levels in liver and diaphragm muscles, which is an undesirable condition for the normal physiological function of tissues. Copyright (c) 2012 John Wiley & Sons, Ltd.
Esophageal Foreign Bodies
(derman Medical Publ, 2014) Cobanoglu, Ufuk; Asker, Selvi; Sayir, Fuat
Esophageal foreign body aspiration is a common event which can cause serious morbidity and mortality in the children and adult population. For that reason, early diagnosis and treatment are crucial for preventing these life threateining complications. Children most often ingest coins and toys whereas adults commonly tend to have problems with meat and bones. Esophageal foreign bodies are located at the cricopharyngeus muscle level in 70%, the thoracic esophagus in 1 53/b and the gastroesophageal junction in the remaining 1 5 /u. Symptoms can vary according to the shape and structure of the ingested object, type of location, patient's age and complications caused by the foreign body. Delay in treatment, esophageal perforation and an underlying esophageal disease are poor prognostic factors. In treatment, observation. foley catheter, rigid or flexible esophagoscopy and removing the foreign body with a Magill forceps, pushing the foreign body into the stomach, giving intravenous glucagon and surgical treatment methods can be used. Rigid esophagoscopy is an effective arid safe procedure for foreign body diagnosis and removal. Improved endoscopic experience and clinical management of thoracic surgeons led to reduced morbidity and mortality in recent years. Most of those emergencies of childhood are preventable. Family education is very important.
Factors Affecting Survival in Non-Small Cell Lung Cancer Invading the Chest Wall
(Scientific Publishers india, 2017) Sehitogullari, Abidin; Aydemir, Yusuf; Sayir, Fuat
Aim: The current study aimed to evaluate the factors affecting survival in non-small cell lung cancer invading the chest wall. Method: A total of 45 cases operated on for Non-Small Cell Lung Cancer invading the chest wall (NSCLC) were followed-up for five years. The effects of factors such as depth of tumor invasion of the chest wall (parietal pleura, extra pleural fatty tissue, intercostal muscles, and rib involvement), perinodal involvement, "N" involvement, surgical margin of the resection, and adjuvant chemotherapy on prognosis and survival were evaluated. Results and discussion: The number of males and females among the cases was 38 (84%) and seven (16%), respectively, with a mean age of 55 +/- 8 years (42-74). Chest wall resection and extra-pleural resection was performed in 36 (80%) and nine (20%) cases, respectively. In the multivariate analysis, factors positively affecting survival were depth of invasion, tumor dimension less than 5 cm, N0 lymph node status, complete resection, and complete adjuvant chemotherapy. Full-thickness resection of the chest wall was an important prognostic factor for long-term survival in all patients with NSCLC invading the chest wall. Conclusion: The stage of the tumor and histopathological factors such as lymphatic involvement, extrapleural invasion, and rib invasion have been shown to gain importance in improvement of survival, in addition to advancements in surgical techniques. Although there is no consensus on the surgical approach in presence of chest wall invasion, we suggest that "en bloc" resection should be preferred to extra-pleural resection.
A Foreign Body Aspiration Showing Migration and Penetration: Hordeum Murinum
(derman Medical Publ, 2012) Sayir, Fuat; Cobanoglu, Ufuk; Sertogullanndan, Bunyamin; Mergan, Duygu
Aspiration of foreign bodies is an important cause of mortality and morbidity in the childhood period. Very rarely seen among the tracheobronchial foreign body aspirations is the Hordeum Murinum, which has an atypical clinical presentation. It may cause unavoidable sequelae in the bronchial system requiring surgery, like bronchiectasis and destruction of the lung parenchyma in patients with delayed diagnosis. Hordeum Murinum, which is hard to pull out due to its progressive nature, may cause interesting clinical pictures. In this study, a case of Hordeum Murinum aspiration is reported which has been diagnosed early due to hemoptysis could be pulled out by thoracotomy after negative bronchoscopy.
Hydrocarbon Pneumonitis; Clinical and Radiological Variability
(derman Medical Publ, 2015) Sertogullarindan, Bunyamin; Bora, Aydin; Sayir, Fuat; Ozbay, Bulent
Aspiration of hydrocarbons causes respiratory pathologies from simply to critical. Our aim is to attract attention to clinical and radiological variability in these cases. We presented a 22-year old young case exposed to diesel fuel by accidental aspiration. Three days after the aspiration, because of clinical deterioration, he was admitted to our emergency clinic. In the chest radiograph on admission showed infiltration in the right middle lobe. But a right lower lobe atelectasis emerged two days later. Bronchoscopy revealed inflamed and hyperemic mucosa and no bronchial obstruction. No secondary bacterial pneumonia was seen. The patient was treated with systemic steroids and antibiotics. After two weeks of treatment there was complete clinical improvement and significant radiologic regression. In the hydrocarbon aspiration cases clinical picture is variable. Radiological picture may develop with a delay. Unless there is a new evidence for an important complication, the steroid treatment should be followed.
An Ideal Choice in the Diagnosis of Interstitial Lung Diseases: Video- Assisted Thoracoscopic Surgery
(derman Medical Publ, 2012) Cobanoglu, Ufuk; Sayir, Fuat; Mergan, Duygu
Aim: Interstitial lung diseases are a heterogeneous group of diseases with a known or unknown etiology affecting the interstitium of the lung. In this study, our experience in the lung biopsy performed by video-assisted thoracoscopic surgery and open lung biopsy for interstitial lung diseases is discussed. Material and Method: In this study, we reviewed 31 patients with a clinical diagnosis of interstitial lung disease who underwent open or thoracoscopic lung biopsy between the years of 2004 and 2010. The cases were examined retrospectively for the age, sex, radiological appearance, operative time, chest tube duration, postoperative hospital stay and the complications. Thoracotomy was performed to 19 of the patients (61.30%) while twelve patients (38.70%) underwent video-assisted thoracoscopic surgery. Result: Fourteen of the cases (45.16%) were male while 17 patients were female (58.06%) with a mean age of 40.83 +/- 15.537 (18-69). Nonspecific interstitial fibrosis constituted the most of the certain diagnoses (29.27%). Operative time, chest tube duration and postoperative hospital stay were significantly shorter in video-assisted thoracoscopic surgery group (p values were 0.018, 0.001 and 0.011 respectively). The overall morbidity rate was 12.90% and there was no mortality. Discussion: In spite of recent advances in clinical diagnostic techniques, lung biopsy is the gold standard for the diagnosis of interstitial lung disease. In our opinion, video-assisted thoracoscopic surgery should be the first choice in the diagnosis of interstitial lung diseases, since these patients can be discharged early as a result of shorter chest tube duration and hospital length of stay.
Impact of Lymph Node Metastases in Esophageal Carcinoma Patients Is Independent of Patient Age
(Asian Pacific Organization Cancer Prevention, 2011) Sehitogullari, Abidin; Cikman, Oztekin; Sayir, Fuat; Cobanoglu, Ufuk; Demir, Cengiz; Demir, Halit
Objective: The purpose of the present study was to define the clinicopathological features and prognosis of esophageal cancer. Methods: Between 2004 and 2009, 128 patients with esophageal cancer were enrolled in a retrospective database and divided into two groups on the basis of number positive lymph nodes with the cutoff as four. Results: The findings for 18 patients (14.0%) Group A were compared with those of 110 patients Group B. In the group A, there were significantly more women (12/6 vs. 54/56, P < 0.001). In both groups, the most frequent histological morphology was squamous cell carcinoma (83% and 75%, respectively), although the percentages were significantly different (P < 0.005). In the group A, lesions were more frequently located in the middle one-third of the esophagus than in the group B (61% vs. 28%, P < 0.001). Group A was more likely to be Stage IIa. Survival rates in group A patients at 5 years after resection were 15.8%, similar to those in group B patients (12.1%, difference not significant). Local lymph node metastases and microscopic residual tumor at the line of resection were also more prevalent in the young patients, but not to a statistically significant degree. Conclusions: These findings suggested that the clinical and pathologic features of carcinomas of the esophagus in young patients do not significantly differ from those in older patients.