Browsing by Author "Sel, Tevhide"

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Serum Selenium, Vitamin E, and Sialic Acids Concentrations in Lambs With White Muscle Disease
(Humana Press inc, 2008) Deger, Yeter; Mert, Handan; Mert, Nihat; Yur, Fatmaguel; Kozat, Sueleyman; Yoruk, Ibrahim H.; Sel, Tevhide
The aim of this study was to determine the serum concentrations of selenium, vitamin E, and total- and lipid-bound sialic acid (LBSA) in lambs with white muscle disease (WMD) before and after treatment with a commercial preparation containing selenite and vitamin E. Fifteen lambs with WMD and ten control animals were used as research materials. Blood samples were collected from both groups before- and 1 month after treatment for Se analysis by fluorimetry, whereas vitamin E and sialic acid were measured by HPLC and spectrophotometry, respectively. Compared to controls, in the diseased animals, there was a significant increase of serum total sialic acid (TSA) and LBSA, together with significant decreases of serum Se and vitamin E concentrations (p < 0.001). One month after treatment, a reversal of trend was observed with decreases of TSA and LBSA and increases of Se and vitamin E concentrations. The TSA and LBSA levels, however, remained significantly higher than those of the controls, p < 0.05 and 0.001, respectively. The Se and vitamin E concentrations of the treated animals were the same as those of controls. This is the first study on total and LBSA concentrations in lambs with WMD, showing that these markers can be used in the prognosis of the disease.
Studies on Serum Α-Tocopherol, Selenium Levels and Catalase Activities in Lambs With White Muscle Disease
(Natl veterinary Research inst, 2007) Kozat, Suleyman; Gunduz, Handan; Deger, Yeter; Mert, Nihat; Yoeruek, Wakki; Sel, Tevhide
This study was conducted to evaluate the effects of combined deficiencies of Se and vitamin E on catalase activity in order to investigate the possible interactions between Se, alpha-tocopherol, and catalase in lambs with white muscle disease (WMD). Ten healthy and fifteen WMD affected lambs of the Akkaraman breed were used. Serum a-tocopherol and Se levels, and catalase activity were analysed. The catalase activity as well as a-tocopherol and Se levels in lambs with WMD before the treatment (day 0), were found to be lower than those of the control group (P<0.001). Therefore, the catalase activity should be taken into consideration in lambs with WMD.