Browsing by Author "Sertogullarindan, B."

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Brucella Related Mediastinal Lymph Nodes Enlargement
(Amer Thoracic Soc, 2015) Sertogullarindan, B.; Ekin, S.; Gunbatar, H.; Olmez, S.
A Case of Viral Myocarditis Presenting With Acute Asthma Attack
(Wiley-blackwell, 2011) Sertogullarindan, B.; Ozbay, B.; Gumrukcuoglu, H.; Akil, M.; Bilgin, M.
Circulating Betatrophin Levels Are Associated With the Apnea-Hypopnea Index and Lipid Profile in Subjects With Obstructive Sleep Apnea
(Wiley-blackwell, 2016) Sertogullarindan, B.; Komuroglu, A. U.; Ucler, R.; Gunbatar, H.; Sunnetcioglu, A.; Bozan, N.; Dalli, A.
Clinical and Prognostic Features of Patients With Pandemic 2009 Influenza a (H1n1) Virus in the Intensive Care Unit
(Makerere Univ, Fac Med, 2011) Sertogullarindan, B.; Ozbay, B.; Gunini, H.; Sunnetcioglu, A.; Arisoy, A.; Bilgin, H. M.; Baran, A., I
Objective: To investigate the clinical and prognostic features of patients admitted to intensive care unit (ICU) with pandemic 2009 influenza A (H1N1) virus. Methods: Patients admitted to the intensive care unit for severe pneumonia associated with pandemic 2009 influenza A (H1N1) virus were evaluated. Results: The study included 20 patients with the mean age of 36 +/- 13. Of the 20 subjects, 17 (85%) had underlying conditions. Of the 20 patients, 11(55%) were discharged and 9 (45%) died. Cardinal symptoms were fever, myalgia, and hemoptysis with the rates of 85 %, 75 % and 45 %, respectively. All patients had pneumonic infiltrations in their chest roentgenograms. Main laboratory findings were lymphopenia, high creatin phosphokinase (CPK) and Lactate dehydrogenase (LDH) levels. All patients had positivity on real time reverse transcription-polymerase chain reaction (RT-PCR). None of the patients had pandemic 2009 influenza A (H1N1) virus vaccination. None of them had taken oseltamivir within 48 hours. Main reasons for mortality were cardiovascular complications and ventilatory associated pneumonia due to Acynetobacter baumannii. Conclusion: Early diagnosis and antiviral treatment in these cases seem to be the best approach to avoid serious illness. Special attention should be given to patients having underlying conditions such as cardiovascular and pulmonary diseases and pregnancy.
The Correlation Between Red Blood Cell Distribution Width Levels With the Severity of Obstructive Sleep Apnea and Carotid Intima Media Thickness
(International Scientific Literature Inc., 2014) Gunbatar, H.; Sertogullarindan, B.; Ekin, S.; Akdag, S.; Arisoy, A.; Sayhan, H.
Background: Obstructive sleep apnea syndrome (OSAS) is characterized by repetitive collapse of the upper airway during sleep. Red blood cell distribution width (RDW) increases platelet activation and has been reported as an independent predictor of adverse outcomes in the general population and is believed to be associated with cardiovascular morbidity and mortality. We evaluated RDW, mean platelet volume (MPV), and platelet distribution width (PDW) as a severity index in OSAS and the relationship between carotid intima media thickness and pulmonary hypertension.; Material/Methods: The study population consisted of 99 patients who were admitted to the sleep laboratory. Based on the apneahypopnea index, patients were grouped into 3 OSAS severity categories. Morning blood samples were withdrawn from patients after a 12-hour fasting period. MPV, PDW, and RDW were measured in a blood sample. Bilateral common carotid arteries of the patients were scanned.; Results: Ninety-nine patients – 73 with OSAS and 26 simple snoring control cases – were included. Mean values of MPV, PDW, and RDW were similar in patients compared to simple snoring subjects in the control group (p=0.162, p=0.656, p=0.091). RDW showed an inverse correlation with mean desaturation and lowest desaturation (p<0.01). Body mass index, apnea-hypopnea index, pulmonary artery pressure, and desaturation time under 90% were positively correlated with RDW (p<0.05). MPV, PDW, and carotid intima media thickness had no correlation with any other parameters.; Conclusions: The study showed a positive relationship between RDW and the apnea-hypopnea index and systolic pulmonary hypertension in patients with OSAS. © Med Sci Monit, 2014.
Does Hypoxia Only Importan for Fatty Liver in Osa Patients
(Amer Thoracic Soc, 2016) Sertogullarindan, B.; Bulut, D.; Gunbatar, H.; Sunnetcioglu, A.; Ekin, S.; Arisoy, A.
Presented With Central Nervous System Involvement, Extra- Pulmonary and Intra-Pulmonary Tuberculosis Combined Infection in a Dialysis Patient
(Yuzuncu Yil Universitesi Tip Fakultesi, 2015) Gunbatar, H.; Bulut, G.; Soyoral, Y.; Sertogullarindan, B.; Ebinc, S.
The clinical appearance of Mycobacterium tuberculosis (TB) in patients on dialysis are substantially non-specific that makes diagnosis difficult. We report a case of extrapulmonary and intrapulmonary TB in end stage renal disease (ESRD). A 58- year-old female with ESRD was admitted to emergency with the complaints of intermittent fever, weakness, impairment of consciousness for last three days. Because of mental confusion she was entubated, transferred to the intensive care unit. Thorax CT showed widespreadcentryasinarnodules in both lungs. The empirically anti-TB therapy was initiated. There was in size of 4x5 cm palpable lymphadenopaty on left supraclavicular region, excisional biopsy revealed caseating granulomatous lymphadenitis. Lumbar puncture was performed and analysis was consistent with TB meningitis. The patient was diagnosed as miliary TB, TB meningitis and TB lymphadenitis and died on the tenth day on admission. Increased awareness of TB in the ESRD population, early diagnosis and treatment are very important. © 2015, Yuzuncu Yil Universitesi Tip Fakultesi, Universitas Indonesia. All rights reserved.
Pulmonary Langerhans Cell Histiocytosis: Two Cases With Varied Radiologic Findings
(Yuzuncu Yil Universitesi Tip Fakultesi, 2016) Gunbatar, H.; Yavuz, A.; Sertogullarindan, B.; Ekin, S.; Asker, S.; Sayır, F.; Bayram, I.
Pulmonary Langerhans Cell Histiocytosis (PLCH) is an idiopathic interstitial lung disease with Langerhans cell infiltration in the lung. PLCH X has non-spesific symptoms, and most patients have smoking history. A combination of stellate nodules, reticular and nodular opacities, upper zone cysts or honeycombing, preservation of lung volume and costophrenic angle sparing are highly specific for PLCH. To contribute to the literature, two cases are presented. First case is 30 years old man with 10 pack/years smoking history was admitted with cough and persevering interstitial opacities. Second case is 34 years old man with 15 pack/years smoking history was admitted with persistant cough. On thorax CT the first case had reticulonodular opacities at the perifery of the upper and middle zones, second case had multiple parenchymal cystic nodular lesions. Open lung biopsy performed, immunohistochemical examination CD1a, CD68, S100 detecting antigenpositive and histologically and radiologically confirmed diagnosed of PLCH. © 2016, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Using Propofol for Flexible Bronchoscopy
(Yuzuncu Yil Universitesi Tip Fakultesi, 2015) Arısoy, A.; Demirkiran, H.; Ekin, S.; Gunbatar, H.; Asker, S.; Sertogullarindan, B.
Propofol is a sedative-hypnotic drug with rapid onset and recovery time. There are limited number of studies in which propofol was used for bronchoscopy. In this current study, we evaluated our patients who received propofol sedation for bronchoscopy in our clinic and investigated the usefulness of the procedure for both patients and physicians We prospectively evaluated patients who had bronchoscopy in our clinic between 2012 January and 2013 January. We recorded demographic features, indications for bronchoscopy, procedures of bronchoscopy, duration of the procedures, minor and major adverse events and hemodynamic parameters of the patients. All patients were monitored until they were discharged from the bronchoscopy unit. In total, 97 patients were included in the study. The mean age of the participants was 65 years, 60 of them were male (61%) and 37 were women (39%). Major indications were lung lesions that were suspected to be central or peripheral lung cancer. Other indications were mediastinal-hilar lymph nodes, hemoptysis, tuberculosis, atelectasis, chronic cough and tracheomalacia. Mean propofol dose was 90 mg in patients who had biopsy and 70 mg for those who did not have biopsy. Mean duration of the procedure was 14 minutes in those who had biopsy and 10 minutes in those who did not have biopsy. One patient had epistaxis after receiving topical lidocaine and two patients had respiratory arrest that required ambulation with a mask. Thirty-five patients (36%) had desaturation, which was reversed by providing adequate oxygenation. Propofol is a useful and applicable sedative-hypnotic for patients and physicians for fiberoptic bronchoscopy. © 2015, Yuzuncu Yil Universitesi Tip Fakultesi, Universitas Indonesia. All rights reserved.
Utility of Computed Tomography in Assessment of Pulmonary Hypertension Secondary To Biomass Smoke Exposure
(International Scientific Literature Inc., 2014) Sertogullarindan, B.; Bora, A.; Yavuz, A.; Ekin, S.; Gunbatar, H.; Arisoy, A.; Ozbay, B.
Background: The aim of this study was to investigate the feasibility of main pulmonary artery diameter quantification by thoracic computerized tomography (CT) in the diagnosis of pulmonary hypertension seconder to biomass smoke exposure. Material/Methods: One hundred and four women subjects with biomass smoke exposure and 20 healthy women subjects were enrolled in the prospective study. The correlation between echocardiographic estimation of systolic pulmonary artery pressure and the main pulmonary artery diameter of the cases were studied. Results: The main pulmonary artery diameter was 26.9±5.1 in the control subjects and 37.1±6.4 in subjects with biomass smoke exposure. This difference was statistically significant (p<0.001). The systolic pulmonary artery pressure was 22.7±12.4 in the control subjects and 57.3±22 in subjects with biomass smoke exposure. This difference was statistically significant (p<0.001). Systolic pulmonary artery pressure was significantly correlated with the main pulmonary artery diameter (r=0.614, p<0.01). A receiver operating characteristic (ROC) curve analysis showed that a value of 29 mm of the main pulmonary artery diameter differentiated between pulmonary hypertension and non-pulmonary hypertension patients. The sensitivity of the measurement to diagnose pulmonary hypertension was 91% and specificity was 80%. Conclusions: Our results indicate that main pulmonary artery diameter measurements by SCT may suggest presence of pulmonary hypertension in biomass smoke exposed women. © Med Sci Monit.