Browsing by Author "Solgun, Derya Guengoerdue"

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Synthesis and Biological Properties of Benzyl 2-(oxy)benzoate Silicon Phthalocyanine
(Springer, 2024) Solgun, Derya Guengoerdue; Ozdemir, Sadin; Agirtas, Mehmet Salih; Tollu, Gulsah
Bis-benzyl 2-(oxy) benzoate substituted axially silicon phthalocyanine was synthesized by the reaction of silicon phthalocyanine dichloride and benzyl salicylate compounds. Characterization of the compound was done by FT-IR, 1H NMR, 13C NMR, UV-visible and Mass spectrum. Photochemical and photophysical properties of new silicon phthalocyanine (SiPc) was investigated. Biological properties of SiPc was carried out by several different parameters. The highest antioxidant ability of 73.18% was obtained at 100 mg/L concentration while the lowest antioxidant activity of 38.46% was obtained at 6.25 mg/L concentration. The antimicrobial effects of SiPc were investigated against different bacteria and microfungi. The results regarding the antimicrobial activity of this compound 3 showed that E. faecalis (ATCC 29,212) was the most sensitive microorganism to the tested compounds, while C. tropicalis was the most resistant microorganism. In addition, when the antimicrobial photodynamic treatment of SiPc was examined, a better activity was observed against all microorganisms. DNA fragmentation activity and microbial cell viability of compound 3 was investigated. SiPc showed excellent DNA nuclease activity and 99.96% inhibition of cell viability at 100 mg/L. The effect of compound 3 on antibiofilm activity fabricated by S. aureus and P. aureginosa was also measured and a good biofilm inhibition values of 86.51% and 75.24% was achieved at 50 mg/, respectively. In addition, when the antidiabetic effects of the compounds were examined, it showed an antidiabetic effect of 20.14% at 400 mg/L.
Synthesis of a New Bis-4 Phenoxy Phthalocyaninato Silicon (Iv) and Its Evaluation on Selectivity for Iron (Iii) Ions
(Wiley, 2025) Agirtas, Mehmet Salih; Solgun, Derya Guengoerdue
Axial phthalocyanine compound carrying 4-cumyl phenoxy groups was obtained from the reaction of 4-cumyl phenol with silicon phthalocyanine dichloride (SiPcCl2). The compound was characterized by 1H NMR, UV-visible light, FTIR, and mass spectrum. Electronic properties and photochemical properties of the compound were investigated by UV-visible light spectra. Singlet oxygen production capacity for the compound was investigated, and the singlet oxygen production (Phi triangle) value was found to be 0.14. The sensor potential of the compound was investigated by UV-visible light spectra against magnesium (II) ions (Mg2+), manganese (II) ions (Mn2+), sodium (I) ions (Na+), nickel (II) ions (Ni2+), zinc (II) ions (Zn2+), silver (I) ions (Ag+), barium (II) ions (Ba2+), cadmium (II) ions (Cd2+), copper (II) ions (Cu2+), cobalt (II) ions (Co2+), and iron (III) ions (Fe3+). The selective sensitivity of the phthalocyanine compound only to Fe3+ ions enables the practical analysis of Fe3+ ions in many environments. This study presents an alternative and practically applicable method for the sensitive determination of Fe3+ ions, which have widespread adverse effects on the environment, ecosystem and human health.