Browsing by Author "Sosuncu, Enver"

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Are Blank Cartridge Guns Really Harmless
(Turkish Assoc Trauma Emergency Surgery, 2014) Gulsen, Ismail; Ak, Hakan; Sosuncu, Enver; Bulut, Mehmet Deniz
Blank cartridge guns are devices that discharge sound and gas, but no bullet or shot. These devices are very similar to real guns in the form of their external design and the sound generated during their firing. Although it is widely held in society that these devices are harmless, reports from Turkey and the world have shown that these guns are not entirely innocent. Herein, we present a 26-year-old male with a head injury due to gunshot from a blank cartridge. The purpose of this presentation is to emphasize that these devices are not harmless, contrary to common public opinion.
Chiari Iii Malformation With a Giant Encephalocele Sac: Case Report and a Review of the Literature
(Karger, 2013) Bulut, Mehmet Deniz; Yavuz, Alpaslan; Bora, Aydin; Gulsen, Ismail; Ozkacmaz, Sercan; Sosuncu, Enver
The Effects of Membranous Abnormalities on Mortality and Morbidity in Chronic Subdural Hematomas
(Journal Neurological Sciences, 2015) Ak, Hakan; Gulsen, Ismail; Yaycioglu, Soner; Atalay, Tugay; Demir, Ismail; Sosuncu, Enver; Arslan, Mehmet
Objective: Our aim was to evaluate the effects of membranous abnormalities on morbidity and mortality in chronic subdural hematomas (CSDH). Methodology: This retrospective study included 116 patients operated in three different hospitals during last three years. Patients were analyzed for the presence of trauma, operation type, recurrence, complication/s, presence of membranous abnormalities like thick outer membrane and septa formation, and mortality. Results: The mean age of the patients 62,06 +/- 11.4 ranging between 42 and 87. 78 (67.2%) of them were male and 38 (32.8%) were female The most common predisposing factor was the trauma especially in male gender. The presence of membranous abnormalities played significant effects on recurrence and complication rates. However, it didn't have significant effect on mortality. Conclusion: Trauma is still the most common etiological factor in chronic subdural hematomas. The presence of membranous abnormality in CSDH increases the recurrence and complication rates.
How Frequently External Ventricular Drainage Device Should Be Changed in Children With Ventriculoperitonel Shunt Infection
(Professional Medical Publications, 2015) Gulsen, Ismail; Ak, Hakan; Demir, Nihat; Sosuncu, Enver; Arslan, Mehmet
Objective: The purpose of the presenting study was to determine how frequently external ventricular drainage (EVD) device should be changed in children with ventriculopertienal shunt (VPS) infection during prolonged intravenous antimicrobial therapy. Methods: In this retrospective study, 25 children with VPS infection were evaluated between January 2012 and December 2013. In these children VPS was surgically removed and appropriate antimicrobial therapy was administered according to cerebrospinal culture results. Data noted about how frequently EVD device had been changed, the number of cells on direct observation of cerebrospinal fluid (CSF), glucose and protein levels of CSF, and CSF culture results were obtained from patients' records. Results: Total 25 children were included in the study. The median age was three months (1 and 65 months). In 44% of children, Staphylococcus epidermidis was isolated. During treatment period, EVD catheter has changed one to six times. A total of 68 EVD catheters were changed in these patients. When the duration of ventriculostomy catheter and leukocyte count in CSF were evaluated on daily basis, leukocyte count was decreased 5 units per day in children whose catheter remained less than 10 days. However, in children whose catheter remained more than 10 days leukocyte count was decreased 2.21 units per day. Conclusions: In children with VPS infection, EVD device should be changed at every 10 days for the rapid resolution of the infection.
Resveratrol Treatment Prevents Hippocampal Neurodegeneration in a Rodent Model of Traumatic Brain Injury
(Turkish Neurosurgical Soc, 2017) Atalay, Tugay; Gulsen, Ismail; Colcimen, Nese; Alp, Hamit Hakan; Sosuncu, Enver; Alaca, Ilker; Ragbetli, Murat Cetin
AIM: Traumatic brain injury (TBI) is a complex process. Increasing evidence has demonstrated that reactive oxygen species contribute to brain injury. Resveratrol (RVT) which exhibits significant antioxidant properties, is neuroprotective against excitotoxicity, ischemia, and hypoxia. The aim of this study was to evaluate the neuroprotective effects of RVT on the hippocampus of a rat model of TBI. MATERIAL AND METHODS: Twenty eight rats were divided into four groups. A moderate degree of head trauma was induced using Feeney"s falling weight technique. Group 1 (control) underwent no intervention or treatment. Head trauma was induced in Group 2 (trauma) and no drug was administered. Head trauma was induced in Group 3 and low-dose RVT (50 mg/kg per day) was injected. In Group 4, high-dose RVT (100 mg/kg per day) was used after head trauma. Brain tissues were extracted immediately after perfusion without damaging the tissues. Histopathological and biochemistry parameters were studied. RESULTS: Brain tissue malondialdehyde (MDA) levels in the trauma group were significantly higher than those in the control, lowdose RVT-treated, and high-dose-RVT-treated groups. The superoxide dismutase (SOD) levels in the control group were significantly higher than those in the trauma, low-dose RVT-treated, and high-dose RVT-treated groups. Glutathione peroxidase (GSH-Px) levels in the control group were significantly higher than those in the trauma and low-dose RVT-treated groups. The level of oxidative deoxyribonucleic acid (DNA) damage (8-OHdG/106 dG) in the trauma group was higher than that in the control group, low-dose RVT-treated, and high-dose RVT-treated groups. CONCLUSION: Resveratrol has a healing effect on neurons after TBI.
Spontaneous Rapid Resolution of Acute Epidural Hematoma in Childhood
(Hindawi Ltd, 2013) Gulsen, Ismail; Ak, Hakan; Sosuncu, Enver; Yavuz, Alpaslan; Kiymaz, Nejmi
Acute epidural hematoma is a critical emergency all around the world, and its aggressive diagnosis and treatment are of vital importance. Emergent surgical evacuation of the hematoma is known as standard management; however, conservative procedures are also used for small ones. Spontaneous rapid resolution of these hematomas has also been reported in eight pediatric cases. Various theories have been proposed to explain the underlying pathophysiology of this resolution. Herein, we are reporting a new pediatric case with spontaneously resolving acute epidural hematoma 12 hours after admission to the emergency room.