Browsing by Author "Sultanoglu, Yilmaz"

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Comparison of Enalapril, Candesartan and Intralesional Triamcinolone in Reducing Hypertrophic Scar Development: an Experimental Study
(Springer, 2018) Demir, Canser Yilmaz; Ersoz, Muhammet Eren; Erten, Remzi; Kocak, Omer Faruk; Sultanoglu, Yilmaz; Basbugan, Yildiray
The purpose of this study was to compare the effects of oral enalapril, an angiotensin-converting enzyme inhibitor (ACE-I), oral candesartan, an angiotensin receptor blocker (ARB), and intralesional corticosteroid treatments in reducing scar formation. Twenty male rabbits were divided into five study groups: A (sham), B (control), C (ACE-I), D (ARB) and E (intralesional corticosteroid). The rabbit ear hypertrophic scar model was used. The hypertrophic scars were photographed and analyzed with the program ImageJ quantitatively to determine the degree of collagen fibers. The scar elevation index (SEI) was calculated at the end of the 40th day. Tissue samples were stained with hematoxylin and eosin and Masson's trichrome and examined under light microscopy for the determination of fibroblast number, epithelization, vascularization, inflammation and fibrosis. The SEI was the highest in the control group with the highest number of fibroblasts under the epithelium. In the steroid group, the SEI was significantly lower than both the ACE-I (p: 0.02) and ARB (p: 0.001) groups. The density of type 1 collagen fibers was the lowest in the control group, whereas type 3 collagen fibers were highest in that group. The ACE-I and ARB groups were similar regarding densities of type 1 and type 3 collagen fibers. The density of type 1 collagen fibers was the highest in the steroid group, whereas the density of type 3 collagen fibers was the lowest in that group. Enalapril, candesartan and intralesional steroid therapies were all effective in reducing scar tissue development; however, enalapril and steroid groups revealed better results. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
A Forgotten Disease "leprae" and Limb Lesions
(Medknow Publications & Media Pvt Ltd, 2016) Oksuz, Mustafa; Kocak, Omer Faruk; Yuce, Serdar; Topkara, Adem; Sultanoglu, Yilmaz
Leprae, which is a forgotten infectious disease, presents with primary findings of skin lesions and peripheral nerve lesions. Neuropathic ulcers are frequently found and may cause deformities, particularly in the extremities. It should not be forgotten that malignant tumors seen on the floor of chronic ulcers can also be seen on the floor of neuropathic ulcers depending on leprae. In our study, a 61-year-old male patient with an ulcerated and unhealed lesion in the volar surface of the second finger of his right hand that existed for approximately 6 months is presented. Although leprae is not common these days, early defect repairs will prevent osteomyelitis and sequelae of amputation, depending on the malignancy in these patients.
Inferior Pedicle Reduction Mammoplasty With or Without Tourniquet: a Comparative Study
(Springer, 2017) Demir, Canser Yilmaz; Sultanoglu, Yilmaz; Kocak, Omer Faruk; Ersoz, Muhammet Eren
To compare the perioperative findings of inferior pedicle reduction mammoplasty (IPRM) performed with or without a tourniquet. This study was carried out in the plastic and reconstructive surgery department at a tertiary care center on a total of 42 consecutive women scheduled for IPRM. Patients in Group I (n = 21) underwent surgery using a tourniquet, whereas patients in Group II (n = 21) were operated on without a tourniquet. Levels of hemoglobin (Hb), hematocrit (Hct), Hct/Hb ratio, and platelet counts were noted preoperatively and on postoperative 24th and 48th h. Numbers of surgical pads and gauze sponges completely used and dripping with blood were recorded. Duration of operation, the amount of breast tissue excised on both sides, and fluid collected in hemovac drains on 48th h after operation were documented. In Group I, the operative time was significantly shorter (p < 0.001), and numbers of gauze sponges and surgical pads were fewer (p < 0.001 for both). Hemoglobin levels were significantly higher in Group I on postoperative 24th (p = 0.002) and 48th h (p = 0.007). Similarly, hematocrit levels in Group I were higher than those of Group II on postoperative 24th (p = 0.004) and 48th h (p = 0.009). We determined that use of a tourniquet significantly reduced the operative time and blood loss during IPRM. Therefore, our preliminary results support that tourniquet usage is practical and safe, and it may also improve the cost-effectiveness of the procedure.
Reconstruction of the Tibia With a Bipedicle Fibular Flap
(Medknow Publications & Media Pvt Ltd, 2016) Kahraman, Ahmet; Yuce, Serdar; Tekin, Hakan; Canbaz, Yasin; Sultanoglu, Yilmaz
Tibial defects can be caused by trauma, congenital, osteomyelitis, or cancers. The tibia is the main bone for bearing the body. It is a big bone, and the difficulty of the reconstruction of tibia is importance to repair it. The fibular bone is a good provider for repairing the tibia defects. Generally, the repair was planned be a free vascularized flap. The most important disadvantage is the low calibration. In early age in particular, the original thickness of the tibia is reached after the surgery with a good follow-up process and rehabilitation. In this case; a 22-year-old female patient had a multi-part post-traumatic fracture of the left tibia and was administered to our plastic surgery inpatient clinic. The bone defect was reconstructed with a bipedicle fibular flap taken from the same leg. The fibula was embedded into the medulla with a screw plate, and fixation was applied with an external fixator. Wherefore the loss of skin, skin flap of fibula bottomed of perforators was not used. A vascularized anterolateral thigh flap, which was obtained from the other leg, was used to reconstruct the skin defect. One year after surgery, the bone viability was perfect. The integrity of the skeleton was created without shortening the leg. The rehabilitation of the patient was continued for repowering and resizing the fibula up to tibia. In this case report, we wanted to share our experience for repairing the tibia defect with using a bipedicle fibular flap.
Spontaneous Flexor Tendon Rupture Developed in Neurofibromatosis
(Medknow Publications & Media Pvt Ltd, 2014) Yuce, Serdar; Kocak, Omer Faruk; Sultanoglu, Yilmaz; Ersoz, Muhammet Eren; Isik, Daghan
Neurofibromatosis is a disease with an autosomal dominant inheritance pattern and it affects different organ systems. In neurofibromatosis cases, cases with a spontaneous flexor tendon rupture depending on intratendinous neurofibroma proliferation in hand were reported. In our study, tendon rupture in the hand of 34-year-old female patient with neurofibromatosis was presented. Unlike literature in this case, we are of opinion that the disease has degenerative effect instead of neurofibroma mass effect of tendon rupture.