Browsing by Author "Türkyilmaz, G."

Now showing 1 - 2 of 2

Prenatal Diagnosis and Associated Anomalies of Congenital Hand Malformations
(Kare Publishing, 2025) Türkyilmaz, G.; Bütün, Z.; Karaaslan, O.
Objective: Congenital hand malformations (CHM) are prevalent congenital anomalies in the prenatal period. We aimed to assess the prenatal features of CHM, associated genetic syndromes, and postnatal prognosis. Material and Methods: Ultrasound findings, associated anomalies, genetic results, and postnatal course were evaluated in ten cases with CHM in two centers over three years. Results: The mean gestational age at diagnosis was 22.8±2.7 weeks. CHM was isolated in four cases and accompanied by associated anomalies in six fetuses. It was bilateral in six cases. Polydactyly was the most common type of hand malformation. Termination of pregnancy was performed in four fetuses. There was no genetic etiology in isolated cases, and the postnatal course was favorable. Hand malformations with associated anomalies and a genetic syndrome carried a high risk, and the prognosis was poor. Conclusion: Prenatal diagnosis of CHM should prompt a detailed anatomical scan and a comprehensive genetic work-up. In isolated cases, the likelihood of a genetic cause is relatively low. In fetuses with multiple congenital anomalies, genetic etiology is common, and the prognosis is poor. © 2025 Kare Publishing. All rights reserved.
Prevalence of Cytomegalovirus Infection in Pregnant Women in Van, Turkey
(Yuzuncu Yil Universitesi Tip Fakultesi, 2025) Hacıoğlu, L.; Türkyilmaz, G.; Onat, E.; Ates, C.; Karaaslan, O.; Karaman, E.; Şahin, H.G.
This study aimed to investigate the seropositive rates of pregnant women against CMV infection and compare seroprevalence in different age groups in Van. This study aimed to investigate the seropositive rates of pregnant women against CMV infection and compare seroprevalence in different age groups in Van. The CMV serology results of 1665 women screened in the first trimester of pregnancy were evaluated between January 2022 and January 2024. The cohort's pregnant women were divided into three groups based on maternal age to make a comparison. Group 1 consisted of pregnant women aged 18-24, group 2 of pregnant women aged 25-35, group 3 of pregnant women over 35 years old. Categorical values were analysed by the chi-square test. A p-value <0.05 was considered statically significant. The mean maternal age was 29.2±5.9 (range 18-43) years. CMV IgM was positive in 1.6%, 1.3% and 1.2% of women in group 1, group 2 and group 3 respectively. There was no significant difference in CMV IgM positive rates between age groups (p: 0.87). CMV IgG-positive women composed 95.8%, 96.3% and 97.8% of the population and it was similar among groups (p: 0.71). In our cohort 3.5% of women were seronegative and 96.5% were seropositive in CMV serology screening. CMV IgM, IgG were positive in 24 (1.4%) pregnant women CMV IgG avidity was high in 18, low in 4 and intermediate in 2 women. Our results demonstrate that CMV seropositive rate is very high in our region and seroprevalence is similar between young and older women. © 2025, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.