Browsing by Author "Tasdemir, M."

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The Evaluation of Dream Anxiety and Sleep Quality in Hemodialysis Patients
(Kure Iletisim Grubu A.S., 2017) Selvi, Y.; Ozdemir, P.G.; Soyoral, Y.; Tasdemir, M.; Aslan, M.
Sleep problems are prevalent in hemodialysis patients. Although several studies have investigated the sleep quality and its causes in hemodialysis patients, there is no report available on dream anxiety in hemodialysis patients. The aim of this study was to evaluate the sleep quality and dream anxiety in hemodialysis patients. We also investigated related factors which influence sleep quality and dream anxiety. Fifty-Two hemodialysis patients and 38 healthy individuals were included in the present study. The sleep quality and dream anxiety were assessed with Pittsburgh Sleep Quality Index (PSQI) and Van Dream Anxiety Scale (VDAS); respectively. The majority of hemodialysis patients had poor sleep quality (%92.3) in our study. Hemodialysis patients had significantly longer sleep latency, higher sleep disturbances and daytime dysfunction than healthy individuals. Hemodialysis patients had higher global dream anxiety scores than healthy individuals. There was a negative relationship between hemoglobin levels and Global VDAS score. Global PSQI score was negative correlated with serum creatinine and phosphorus levels, while positive correlated with C-reactive protein levels. Our results suggest that hemodialysis patients had poor sleep quality, higher sleep disturbances and daytime dysfunction compared with healthy subjects. Moreover, we demonstrated that dream anxiety was significantly higher in hemodialysis patients.
Evaluation of the Relationship Between Endogenous Gonadotropins and Female Sexual Function and Psychological Status in Predialysis and Hemodialysis Patients
(C I C-edizioni int Srl, 2012) Kurdoglu, Z.; Soyoral, Usul Y.; Tasdemir, M.; Kurdoglu, M.
An Investigation of Protective Effects of Litium Borate on Blood and Histopathological Parameters in Acute Cadmium-Induced Rats
(Humana Press inc, 2018) Yildirim, Serkan; Celikezen, Fatih Caglar; Oto, Gokhan; Sengul, Emin; Bulduk, Mehmet; Tasdemir, M.; Cinar, D. Ali
This study was carried out to determine the protective effects of lithium borate (LTB) on blood parameters and histopathological findings in experimentally induced acute cadmium (Cd) toxicity in rats. Twenty-eight male Wistar albino rats were used, weighing 200-220 g, and they were randomly divided into four groups, including one control and the following three experimental groups: a Cd group (0.025 mmol/kg), a LTB group (15 mg/kg/day orally for 5 days), and a LTB + Cd group (15 mg/kg/day orally for 5 days and Cd 0.025 mmol/kg by intraperitoneal injection on the fifth day). All the rats in the study were anesthetized with ketamine at the end of the sixth day, blood was taken from their hearts, and then the rats were decapitated. The values in the control and LTB group were usually close to each other. White blood cell (WBC), neutrophil %, and C-reactive protein (CRP) levels increased in the Cd and LTB + Cd groups while lymphocyte and monocyte levels decreased in a statistically significant manner, in comparison to the other groups. It was determined that the levels of red blood cells (RBCs), hematocrit (Htc), and hemoglobin (Hb) did not change in the groups. The levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in the Cd and LTB + Cd groups significantly increased, in comparison to the other groups, while the glucose, alkaline phosphatase (ALP), albumin (ALB), and total protein (TP) levels decreased. According to histopathological findings in the control and LTB groups, the liver and kidney tissues were found to have normal histological structures. In the Cd group, severe necrotic hemorrhagic hepatitis, mild steatosis, and mononuclear cell infiltration were detected in the liver. In the LTB + Cd group, degeneration and mild mononuclear cell infiltration were found in the liver. Regarding the kidney tissue in the Cd group, severe intertubular hyperemia in both kidney cortex and medulla, as well as degeneration and necrosis in the tubulus epithelium, was observed. In the LTB + Cd group, mild interstitial hyperemia and mononuclear cell infiltration was detected. Resultantly, it can be said that LTB at this dose has non-toxic effects and some beneficial effects for liver and kidney damage caused by acute Cd toxicity.