Browsing by Author "Tekin, Yasin"

Now showing 1 - 3 of 3

Comparing the Efficiency of Er,cr:ysgg Laser and Diode Laser on Human -Defensin and Il-1 Levels During the Treatment of Generalized Aggressive Periodontitis and Chronic Periodontitis
(Taylor & Francis inc, 2017) Ertugrul, Abdullah Seckin; Tekin, Yasin; Talmac, Ahmet Cemil
Background: The aim of this study is to determine the suitability of the Er,Cr:YSGG and 940 +/- 15-nm diode laser for the treatment of generalized aggressive periodontitis and chronic periodontitis by measuring the levels of human -defensin-1 and IL-1. Patients and Methods: A total of 26 patients were included in this study. The study was designed as a split-mouth experiment. We performed scaling and root planing in the right maxillary quadrant, scaling and root planning + Er,Cr:YSGG laser in the left maxillary quadrant, scaling and root planning + 940 +/- 15-nm diode laser in the left mandibular quadrant, and only scaling and root planing in the right mandibular quadrant. The presence of human -defensin-1 and IL-1 was analyzed with an ELISA. Results: When the baseline and post-treatment human -defensin-1 levels and IL-1 levels of the study groups were evaluated, a decrease in human -defensin-1 and IL-1 were observed in the quadrant where the Er,Cr:YSGG laser was applied in both the generalized aggressive periodontitis group and the chronic periodontitis group. Conclusions: The use of the Er,Cr:YSGG laser at non-surgical periodontal treatment decreased both IL-1 and human -defensin-1 levels. It is likely that Er,Cr:YSGG laser is more suitable for the treatment of generalized aggressive periodontitis and chronic periodontitis.
The Effect of Enamel Matrix Derivatives on Root Coverage: a 12-Month Follow-Up of a Randomized Clinical Trial
(Sociedade Brasileira de Pesquisa Odontologica, 2019) Aydinyurt, Hacer Sahin; Tekin, Yasin; Ertugrul, Abdullah Seckin
Subepithelial connective tissue grafts (SCTGs) with a coronally advanced flap (CAF) are accepted as the gold standard for covering denuded root surfaces. In recent years, enamel matrix derivatives (EMDs) have been used for their regenerative potential in periodontics. The aim of this split-mouth and randomized controlled study was to assess the clinical and aesthetical impacts of EMD application in combination with SCTG+CAF in patients with Miller's Class I and II gingival recessions in contralateral canines of the maxilla. Participants who underwent SCTG+CAF+EMD application were identified as the test group (n = 19) and those who underwent SCTG+CAF as control group (n = 19). The outcome parameters were recession depth/width, root coverage percentage, and root coverage aesthetic score (RES). RES was evaluated by two calibrated blind periodontists one year after the treatment. Statistically significant root coverage percentage was observed at one year post-treatment for both groups (p < 0.05). However, significant differences between the groups were not observed in terms of total RES and complete root coverage rate (p > 0.05). The test group had significantly better results than the control according to the soft tissue texture and mucogingival junction alignment results (p < 0.05). These results indicate that EMDs contribute to the healing of soft tissue without scarring. As a result of better wound healing, the EMD-added group exhibited better results in terms of the harmony of the mucogingival junction between adjacent teeth. This paper is the first split-mouth study in which SCTG+CAF and SCTG+CAF+EMD were compared using RES in bilateral canines.
Il-6, Tnf-Α Levels and Periodontal Status Changes During the Menstrual Cycle
(Wiley, 2018) Aydinyurt, Hacer Sahin; Yuncu, Yusuf Ziya; Tekin, Yasin; Ertugrul, Abdullah Seckin
Objectives Sex steroid hormones are thought to affect periodontal tissues. A clear understanding of the effect of the menstrual cycle on oral tissues would be an important milestone in the timing of dental interventions in the future. The aim of this longitudinal, prospective study was to evaluate clinical periodontal parameters and levels of interleukin-6 IL-6 and tumour necrosis factor alpha (TNF-) in gingival crevicular fluid (GCF) during the menstrual cycle. MethodsResultsForty-five patients were included in this study. Clinical periodontal parameters and levels of IL-6 and TNF- were evaluated at three points of the menstrual cycle: menstruation day MD, ovulation day (OD) and premenstruation day (PmD). Levels of IL-6 and TNF- were determined by enzyme-linked immunosorbent assay. There were no statistically significant changes in plaque indexes or probing depths during the menstrual cycle (p>0.006) The differences between OD and PmD for gingival index and bleeding on probing were significant (OD>MD) (p<0.006). Statistically significant differences in TNF- and IL-6 levels in the GCF were observed during the menstrual cycle (PmD>OD>MD) (p<0.006). ConclusionsPeriodontal tissues did not exhibit evident changes, but this study demonstrated that the menstrual cycle affected the periodontium and induced inflammatory situations during the menstrual cycle.