Browsing by Author "Toprak, N."

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Giant Aneurysmal Bone Cyst of the Rib
(TIP ARASTIRMALARI DERNEGI, 2012) Avcu, S.; Toprak, N.; Bulut, M.D.; Ünal, O.
Aneurysmal bone cyst (ABC), especially in the ribs, is a rare disease, considering to be a benign lesion which occurs mostly in children and young adults. This case, however, concerns a 46-year-old female patient, with complaints of pain and palpable mass in the right thoracic wall, who was diagnosed to have ABC originating from the rib demonstrated by radiological examinations, aspiration biopsy, and histopathological verification. Surgical resection was performed to the lesion.
Idiopathic Granulomatous Mastitis and Other Types of Mastitis; Comparison of Ultrasound Findings
(Yuzuncu Yil Universitesi Tip Fakultesi, 2021) Toprak, N.; Gündüz, A.M.
Idiopathic granulomatous mastitis (IGM) is a chronic autoimmune inflammatory condition that can negatively affect patient psychology, that effective diagnostic protocols and treatment plans have not yet been established. Since the treatment protocols used differ, other causes of mastitis should be excluded. The purpose of this study was to compare ultrasonography (US) findings of IGM with type of the other mastitis (OM) to identify the imaging signs essential for a correct differential diagnosis. This retrospective study was approved by the University Ethics Committee. This study was between August 2017 and August 2018. Parenchymal distortion and no discrete mass, mass-like lesions with indistinct borders, tubular connections, duct ectasia-periductal thickening, skin thickening and presence of an abscess were evaluated in US for each breast lesion. The fifty-seven patients with IGM and 38 with OM were included in the study. The mean age was 35.2±8.4 and 43.6±12.5 years for those with IGM and OM, respectively. US showed tubular connections (43(75.4%)) with finger-like projections that tended to coalesce (P˂0.01) and mass-like hypoechoic lesions (51(89.5%)) with irregular margins in IGM. Most cases of OM, 37 (97.4%), had mass-like lesions with indistinct borders. The US findings of IGM sometimes overlap with types of OM. Although core biopsy is typically diagnostic, US findings are very useful in the differential diagnosis of IGM and OM. Especially, observation of tubular-related hypoechoic mass-like lesions may suggest IGM in the reproductive age patient with chronic mastitis. © 2021, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Mixed Type Adrenal Cyst: a Case Report
(Yuzuncu Yil Universitesi Tip Fakultesi, 2015) Bulut, G.; Bulut, M.D.; Yilmaz, D.; Celik, S.; Toprak, N.
Adrenal cysts are rare lesions that usually progress asymptomatically. They are often determined postmortem. Our case was a 50-year old-male who had presented to our clinic with upper right quadrant pain. The computed tomography demonstrated a cystic mass in the adrenal gland. No abnormalities were determined in the laboratory tests. According to the histopathological and immunohistochemical examination, the cyst was evaluated as a mixed-type adrenal cyst, the wall of which was covered with endothelium, mesothelium and cubic epithelium. We believed that the case was worth presenting, since it was the first diagnosed mixed-type adrenal cyst in the literature. © 2015, Yuzuncu Yil Universitesi Tip Fakultesi, Universitas Indonesia. All rights reserved.
Pituitary Imaging Findings in Pediatric Patients With Idiopathic Hypogonadotropic Hypogonadism
(Sciendo, 2023) Bitkin, E.C.; Toprak, N.; Karaman, S.
Objective. Idiopathic hypogonadotropic hypogonadism in children is a disease leading to a puberty absence. Some hypothalamic and pituitary defects cause hypogonadotropic hypogonadism. Pituitary magnetic resonance imaging is routinely performed in these patients. In our study, we provide an information about pituitary pathologies associated with an idiopathic hypogonado-Tropic hypogonadism in childhood. Methods. Twenty-Two patients, who were admitted to the pediatric endocrine outpatient clinic of our hospital because of their undeveloped secondary sex characteristics during adolescence, were included in our study. Age, gender, history, physical examination findings, and laboratory tests were recorded in patients. Pituitary magnetic resonance imaging results were examined. The criteria for the diagnosis of hypogonadism were: Absence of puberty or delayed puberty, clinical signs or symptoms of hypogonadism, and presence of low or normal gonadotropin levels. Results. In the present study, 22 patients were diagnosed with hypogonadotropic hypogonadism. The mean age of the patients was 15.90±1.09 years. Basal and stimulated luteinizing hormone and follicular stimulating hormone levels of the patients were found to be low. Prolactin, cortisol, adrenocorticotropic hormone, free thyroxine, and thyroid stimulating hormone levels were within normal limits in all patients. The pituitary magnetic resonance imaging revealed six patients with pituitary adenoma, one with empty sella turcica, and five with pituitary hypoplasia. Conclusions. The present data showed that in the presence of hypogonadotropic hypogonadism, the hypothalamic-pituitary abnormalities are more likely to be present in the children compared to the adult population. Thus, it can be strongly emphasized the importance of the pituitary imaging examination, especially in the idiopathic hypogonadotropic hypogonadism cases. © 2023 Eda Celebi Bitkin et al., published by Sciendo.