Browsing by Author "Tunc, Serap Keskin"

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Clinical and Histological Evaluation of the Efficacy of Antimicrobial Photodynamic Therapy Used in Addition To Antibiotic Therapy in Pericoronitis Treatment
(Elsevier Science Bv, 2018) Eroglu, Cennet Neslihan; Tunc, Serap Keskin; Erten, Remzi; Usumez, Ashhan
Background: Although antimicrobial efficacy of photodynamic therapy has been studied several times, there is no study investigating its efficacy on pericoronitis. This study aimed to determine whether antimicrobial photodynamic therapy combined with antibiotic therapy is clinically and histologically superior to antibiotic therapy alone in pericoronitis treatment. Methods: Patients (n = 40) with pericoronitis were divided into two groups (20 patients for each) to receive either antibiotic + indocyanine green + 810 nm wavelength diode laser (antimicrobial photodynamic therapy group) or antibiotic alone. Initial biopsy samples were obtained from the affected tissue of the patients at their first presentation to the clinic before any intervention. The second biopsy samples were obtained on the 3rd day of treatment in both groups from the tissue part not biopsied before; tooth extraction was then performed. All tissue samples were histologically examined to assess inflammatory cell response. Patients' pain (using Visual Analogue Scale) and lymphadenopathy (presence or absence) were clinically evaluated in the first 3 days and on the 7th day of treatment. Results: In the antimicrobial photodynamic therapy group, 100% improvement was achieved regarding pain and lymphadenopathy at the end of the 7th day. Comparison of the inflammatory cell scores of the 2nd biopsy samples between the antibiotic alone and antimicrobial photodynamic therapy groups revealed a significant difference in favor of antimicrobial photodynamic therapy group. Conclusions: Antimicrobial photodynamic therapy combined with antibiotic therapy for pericoronitis treatment was found to be more successful as compared with the antibiotic therapy alone regarding clinical and histological outcomes.
Comparison of Knowledge, Awareness, and Behaviors Toward Oral Cancer Among Dental Students and Dentists: an Online Cross-Sectional Questionnaire in Türkiye
(Bmc, 2024) Tunc, Serap Keskin; Toprak, Mehmet Emin; Yuce, Esra; Efe, Nihat; Topbas, Celalettin
Objective This cross-sectional online questionnaire-based study evaluated the knowledge, awareness, and behaviors of dentists and senior dental students regarding oral cancer (OC). Materials and methods This study included 168 dentists and senior dental students who had completed all theoretical educations and clinical practices. An online survey was administered to all participants to assess their awareness of the risk factors for OC, clinical knowledge, and behaviors. The participants' demographic characteristics and knowledge of OC were analyzed. Results Of the participants, 48.8% were female and 51.2% were male. Their mean age was 27.04 +/- 5.56 years (range: 21-51). In addition, 59.5% were dentists, and 40.5% were senior dental students. The dentists' mean time since graduation was 6.38 +/- 5.64 years (range: 1-27). Routine oral mucosa examination for OC was significantly more frequent among the dentists than the senior dental students (p < 0.05). Among all participants, 33% of dentists and 51.5% of senior dental students had poor knowledge of OC-related or possibly predisposing factors. Routine evaluation of OC-related and predisposing risk factors, including human papillomavirus infection, smoking, alcohol use, trauma-related non-healing oral lesions caused by long-term incompatible prostheses, and poor oral hygiene, was significantly more frequent among the dentists than the senior dental students (p < 0.05). Conclusion Educating dental students about a more comprehensive oral examination and early diagnosis of OC would help overcome the current lack of adequate knowledge and attitudes in OC prevention and early detection. A core curriculum compatible with the global standards on OC should be provided to dental students.
Corticosteroid Injection in the Treatment of a Huge-Size Central Giant Cell Granuloma in Children: a Case Report
(Elsevier, 2024) Tunc, Serap Keskin; Efe, Nihat; Ertas, Umit
Central giant cell granulomas (CGCGs) of the jaw are benign intraosseous and osteolytic lesions. Their clinical presentation includes atypical aggressive lesions that cause severe damage early in life, and aggressive treatment is necessary in most cases to prevent recurrence. Curettage is the most preferred therapy, but in recent years, conservative therapy is also commonly used. Corticosteroid injection treatment, a conservative method, was planned for a developing male patient with difficulty in diagnosis and treatment due to the complications of resection. After clinical and radiologic evaluation of the patient, incisional biopsy was performed and the diagnosis of SDHG was made. The patient was treated with intralesional corticosteroids once a week for eight weeks. Since the patient 's treatment was interrupted for 2 months due to the Covid-19 outbreak, 2 doses of intralesional corticosteroid (Sinakort-A 40 mg) were administered and the patient was followed up. At 12 months, clinical and panoramic radiographic examination revealed no pathologic findings related to the lesion. In this article, we report a pediatric case of giant CGCG successfully treated with intralesional corticosteroid injection.
The Effect of Vocational Awareness Level on Dental Anxiety and Oral Health Among the Students of Dentistry
(Kerman Univ Medical Sciences, 2019) Yayli, Nazli Zeynep Alpaslan; Tunc, Serap Keskin; Kaki, Gulter Devrim; Altindal, Dicle
BACKGROUND AND AIM: The purpose of this study was assessing oral health status and dental anxiety differences between the freshman and senior dental students and the effect of awareness on dental practices. METHODS: Freshman (n = 71) and senior dental students (n = 41) were included in this study. All participants were applied Corah Dental Anxiety Scale (C-DAS) and asked for the frequency of dental visits in a year. Gingival index (GI), plaque index (PI), bleeding on probing (BOP), probing depth (PD), clinical attachment level (CAL), and decayed, missing, and filled teeth (DMFT) index were recorded. Number Cruncher Statistical System (NCSS) program and Shapiro-Wilk, t, Mann-Whitney U, Pearson chi-square, and Fisher-Freeman-Halton tests were used for statistical analysis (P < 0.0500). RESULTS: C-DAS score of the freshman students was found significantly higher than the senior students (P < 0.0500). There was a statistically significant difference in the frequency of dental visits between freshman and senior students (P < 0.0010). GI, PI, and BOP values of the freshman students were significantly higher than the senior students (P < 0.0010). There was no statistical differences between PD and CAL measurements (P > 0.0500). It was found that the DMFT index of freshman students was significantly higher than the senior students (P < 0.0010). CONCLUSION: This study has shown that dental anxiety decreases as awareness and consciousness increase in terms of dental practice. More anxious participants' oral health is weak, individuals with high dental anxiety make fewer visits to the dentists and need more dental practices.
Effectiveness of Single Session of Low-Level Laser Therapy With a 940nm Wavelength Diode Laser on Pain, Swelling, and Trismus After Impacted Third Molar Surgery
(Mary Ann Liebert, inc, 2016) Eroglu, Cennet Neslihan; Tunc, Serap Keskin
Introduction: In low-level laser therapy (LLLT), applications are generally performed in repetitive sessions using wavelengths of around 800nm, at which the depth of penetration of laser is greater. The present study aimed to investigate the effects of LLLT with a 940nm diode laser, which was performed extraorally on all the primarily and secondarily affected areas immediately after surgery in a single session, on pain, swelling, and trismus that occurred after impacted tooth extraction. Materials and methods: Thirty-five outpatients with similarly impacted lower third molars on both sides were selected. The teeth of patients were removed in two separate operations. Postoperatively, the patients received laser therapy with energy of 4J/cm(2) on one side and no laser energy was applied to the other side (placebo side). Swelling, trismus, and subjective assessment of pain on a visual analog scale were evaluated and compared between the laser-treated and placebo sides. Results: There was no statistically significant difference in pain, swelling, or trismus between the sides (Mann-Whitney U test p>0.05). However, according to the clinical outcomes, swelling and trismus were less in the laser-treated side than in the placebo side. Conclusions: A single-session LLLT that would be applied with a diode laser immediately after impacted tooth extraction might help patients to be less affected by postoperative trismus and swelling.
Evaluation of Risk Factors for External Root Resorption and Dental Caries of Second Molars Associated With Impacted Third Molars
(W B Saunders Co-elsevier inc, 2020) Tunc, Serap Keskin; Koc, Alaettin
Purpose: Impacted third molars (M3s) may lead to external root resorption (ERR) and dental caries (DC) in the adjacent second molars (M2s). The aim of this study was to identify the risk factors for ERR and DC in M2s associated with impacted M3s. Materials and Methods: We implemented a cross-sectional study and enrolled a sample composed of patients with M3s and M2s present and cone-beam computed tomography (CBCT) scans available for review. If there was contact between the M2 and the adjacent M3 and the border of radiolucency was more distinct, the case was considered ERR. Apart from that, the case was considered DC. Potential predictor variables were defined as age, gender, tooth location, M2-M3 contact, root development in M3, M3 inclination, M3 impaction type, and M3 follicular diameter. Outcomes of the study were DC and ERR in M2s. CBCT was used to detect the presence of DC and ERR in M2s. Results: A total of 250 eligible images of M3s in the upper and lower jaws of 167 patients were included. The mean age of the patients with CBCT images available was 26.08 +/- 4 years (range, 18 to 40), and 43.6% of the patients were men. Factors associated with a significantly increased frequency of ERR in M2s included maxillary location, presence of M2-M3 contact, and mesioangular inclination (P < .005). DC in M2s was significantly more likely to occur in those with absence of contact between M2 and M3 (P < .005). Conclusions: The results of this study showed an increased risk of ERR to be associated with maxillary molars, mesioangular inclination, and presence of M2-M3 contact. The variable associated with an increased risk of DC was the absence of M2-M3 contact. (C) 2020 American Association of Oral and Maxillofacial Surgeons
Evaluation of the Effect of Er,cr:ysgg Laser Application on Peri-Implant Crevicular Fluid Receptor Activator of Nuclear Factor-Kappa B Ligand and Osteoprotegerin Levels in the Non-Surgical Treatment of Peri-Implantitis: a Randomized Clinical Trial
(Wiley, 2024) Alpaslan, Nazli Zeynep; Altindal, Dicle; Akbal, Damla; Talmac, Ahmet Cemil; Tunc, Serap Keskin; Ertugrul, Abdullah Seckin
Background: This study aimed to investigate the effect of erbium, chromium doped:yttrium,scandium,gallium,garnet (Er,Cr:YSGG) laser application combined with non-surgical mechanical debridement (MD) on clinical parameters and peri-implant crevicular fluid receptor activator of nuclear factor-kappa B ligand (RANKL) and osteoprotegerin (OPG) levels in the treatment of peri-implantitis. Methods: A total of 49 patients who underwent non-surgical treatment of peri-implantitis were randomly divided into two groups. The control group (n = 26) received MD alone, while the laser group (n = 23) received MD+Er,Cr:YSGG. The clinical parameters (bleeding on probing [BoP], gingival index [GI], plaque index [PI], probing depth [PD]), marginal bone loss (MBL), and biochemical parameters (RANKL and OPG) were measured at baseline (T0) and 6 months after treatment (T1). Results: There was a statistically significant decrease in all the clinical parameters in both groups at T1 compared to T0 (p < 0.05). The BoP, PD, MBL, and RANKL reductions were significantly higher in the laser group than in the control group (p = 0.046, p = 0.014, p = 0.047, p = 0.045, respectively). The OPG levels significantly increased at T1 in the laser group (p = 0.01). The OPG/RANKL ratio increased significantly in both groups at T1, which favored the laser group (p = 0.034). Conclusions: Although both treatment methods were influential in treating peri-implantitis, the laser group (MD+Er,Cr:YSGG) yielded more favorable results by reducing clinical inflammation and improving biochemical parameters. Based on these findings, Er,Cr:YSGG laser may be a beneficial adjunctive treatment in this patient group.
Evaluation the Effects of Low-Level Laser Therapy on Disc Displacement With Reduction
(Baycinar Medical Publ-baycinar Tibbi Yayincilik, 2020) Tunc, Serap Keskin; Degirmenci, Beyza Unalan; Yayli, Nazli Alpaslan; Aslan, Senol; Akdeniz, Mehmet Serif
Objectives: This study aims to evaluate the effects of additional low-level laser therapy (940 nm GaAIAs) to the routine occlusal splint therapy on maximal mouth opening (MMO), visual analog scale (VAS) scores, and passive mouth opening (PMO). Patients and methods: Between January 2016 and March 2018, a total of 40 patients (10 males, 30 females; mean age 22.35 years; range, 18 to 60 years) with disc displacement with reduction of the temporomandibular joint were included. The patients were divided into two groups. Group 1 (control group, n=20) received routine non-steroidal anti-inflammatory drug (NSAID) therapy and occlusal splint therapy for eight hours per day for a total of three months. Group 2 (laser group, n-20) received NSAID, occlusal splint therapy and 940 nm wavelength diode laser therapy for two sessions per week for a total of four weeks. The MMO, PMO, and VAS scores were recorded before and at one, two, three, four, and 12 weeks after treatment. The joint and muscle examinations were performed. Results: A constant decrease was found in the VAS scores in both groups. At four (p=0.008) and 12 weeks (p-0.003), a statistically significant difference in the VAS scores was observed. At all time points, PMO and MMO scores increased in both groups. The MMO scores were statistically higher in the laser group at all time points (p<0.005). Conclusion: Our study results suggest that short-term low-level laser therapy additional to conventional treatment may yield satisfactory outcomes.
Investigation of Nutrition and Disease Conditions With Molecular Bacteria Analysis in a Dental Calculus Sample From 1900s
(Nobel Ilac, 2022) Guducuoglu, Huseyin; Yilmaz, Hakan; Tunc, Serap Keskin; Erdogan, Sabahattin; Ercek, Mikail
Objective: Tepekoy Hoyuk salvage excavations were carried out in the village of Tepekoy, near Mus province and Varto district. Although samples were taken from the historical dental calculus in four skulls from this region, only one individual could be analyzed for DNA, and accordingly, the physiological characteristics and diseases related to the bacteria that this individual was exposed to could be predicted. Material and Method: It was observed that the subject of the study died between the ages of 20-35, had a height between 151-162 cm, and had mild bone osteophytes in his vertebrae. The dental calculus sample of the individual was collected on clean aluminum foil. It was then transferred to a sterile screw tube, UV irradiation was used for the sample decontamination, the bleach process was used for the cleaning and decontamination of the outer surface (4% bleach, sodium hypochlorite, NaCIO), allowed to air dry in a sterile container (petri dish) for up to five minutes, sample powder after reconstitution, it was poured into a sterile screw-cap tube. Isolation was performed on the MagPurix (Zinexts, Taiwan) device using the MagPurix Bacterial DNA Extraction Kit. Accordingly, DNA was obtained in only one of the four samples brought for study. Oxford Nanopore Technology (England) was used for 16S r-RNA isolation and Nanopore Sequence Analysis. Then, bacterial analysis was done up to the genus level with bioinformatics analysis. Results: Bacteria were classified from phlyum level to genus level and the following bacteria took the first place in these classes. At the phylum level; Firmicutes 52.74%, class level; Clostridia 31.55%, order level; Clostridiales 31.55%, family level; Ruminococcaceae 24.29%, at the genus level; Ralstonia 21.48% took the first place. Conclusion: The physiological characteristics and diseases of this individual were linked by the bacteria obtained, and it was predicted that this person was obese, prone to diabetes and especially fed with grains as a diet.
Is Low-Level Laser Therapy a Candidate To Be a Good Alternative in the Treatment of Mucositis in Childhood Leukemia
(Lippincott Williams & Wilkins, 2022) Karaman, Kamuran; Sarica, Ayca; Tunc, Serap Keskin; Karaman, Serap
Background and Aim: Oral mucositis (OM) is a common side effect of systemic chemotherapy (CT) in cancer patients. The aim was to evaluate the effect of low-level laser therapy (LLLT) for the treatment of CT-induced OM children. Patients and Methods: The study was carried out in 40 pediatric patients 3 to 18 years of age, who were hospitalized for the diagnosis of leukemia and underwent CT between June 1, 2019, and December 31, 2019. They were randomly divided into 2 groups with 20 cases in each group. The LLLT group was treated with GaAlAs diode laser (l): 830 nm (infrared), power: 150 mW, dose: 4.5 J/cm(2) and the control group underwent bicarbonate treatment. Patients received intervention for 3 days. The grade of OM was clinically assessed by the World Health Organization (WHO) Common Toxicity Criteria Scale. Visual Analog Scale was used on the same days with OM grade to evaluate the pain status. Results: While there was no significant difference between the groups in terms of OM grade at the beginning of the treatment and on the first, second, fourth, and 11th days of the treatment, the average OM grade of the LLLT group was found to be statistically significantly lower on the third, fifth, sixth, and seventh days of the treatment. The Visual Analog Scale score of the LLLT group was statistically significantly lower compared with the control group at all examinations starting from the first day of treatment (P<0.05). Conclusion: In the treatment of oral OM that occurs in children after CT, both standard care and LLLT treatment improve the grade and pain of OM.
The Relationship Between Abo Blood Types and Survival of Dental Implants
(Kerman Univ Medical Sciences, 2021) Tunc, Serap Keskin; Cigerim, Levent
BACKGROUND AND AIM: Bacteria colonization is the main cause of periodontal diseases and may be effected by ABO blood types. Since implant survival is severely reduced by peri-implant disease, this study aimed to evaluate the marginal bone resorption levels and survival rates of implants which were followed for 1-8 years and analyze these values with respect to demographic data and blood types. METHODS: Patients who had undergone implant treatment and had prosthetic rehabilitation at the School of Dentistry in Van Yuzuncu Yil University, Van, Turkey, between March 2010 and March 2017 were studied in this cross-sectional retrospective study. In this study, 272 individuals were included, and a total of 963 implants were evaluated. Individuals who had implant treatment were called for control visits and clinical and radiological examinations. The effects of blood types were evaluated in terms of implant survival, failing implant, post-operative complications, and mesial-distal marginal bone resorption. Statistical analysis was performed using NCSS 2007 software. The Kruskal-Wallis test, Pearson's chi-square test, Fisher's exact test, and Fisher-Freeman-Halton exact test were used for statistical analysis. Statistical significance level was considered at P < 0.05. RESULTS: The mean age of the participants was 49.49 +/- 11.92 years. The blood types of the participants were O (52.2%), A (30.5%), B (11.1%), and AB (6.3%). The implant survival rate was found to be 98.3%. There was no significant difference between blood types in terms of gender and age (P > 0.05). On the other hand, mesial-distal bone resorption was higher in patients with O blood type older than 50 years (P < 0.05). CONCLUSION: The fact that 52.2% of the patients with implants had O blood type, which is higher than the Turkish general population, may suggest that individuals with O blood type are more prone to tooth loss. To the best of our knowledge, this is the first study that assessed the impact of blood type on the success of dental implants.
Removal of Epulis Fissuratum by Er,cr:ysgg Laser in Comparison With the Conventional Method
(Mary Ann Liebert, inc, 2015) Eroglu, Cennet Neslihan; Tunc, Serap Keskin; Elasan, Sadi
Objective: The present study aimed to compare clinical outcomes during the recovery period after soft tissue surgery performed by an erbium, chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser with those after surgery with the conventional method, in which a scalpel was used. Methods: A total of 44 epulis fissuratum removal surgeries were performed in 30 healthy volunteers using either an Er,Cr:YSGG laser (laser group) or a scalpel (conventional group), with the same number of lesions in each group. Both groups were controlled postoperatively on days 2, 7, 14, and 30. The visual analog scale (VAS) pain scores of the patients and healing, erythema, and suppuration in the surgical area were recorded with scores between 0 and 3. Total wound surface was measured by a ruler according to the Bates-Jensen Wound Assessment Tool. Results: The results of the present study demonstrated that there were no significant differences between the conventional group using analgesic and the laser group in terms of the VAS scores (p=0.744) and edema (p=0.206). Evaluation of wound surface revealed healing without any problem as of the 2nd day at a rate of 82% in the laser group and 59% in the conventional group. Conclusions: In conclusion, Er,Cr:YSGG laser was superior to scalpel regarding clinical outcomes, and led to a difference in the use of analgesic and local anesthetic.
Soft Tissue Schwannomas of the Hard Palate and the Mandibular Mentum
(Hindawi Ltd, 2017) Eroglu, Cennet Neslihan; Tunc, Serap Keskin; Gunhan, Omer
Schwannomas are benign, slow growing, encapsulated tumours that originate from the Schwann cells. Intraoral schwannomas are rare, and most of these tumours involve the tongue. They are rarely located in the hard palate or in the facial soft tissue. Herein, we present the clinical and histological features as well as the prognoses of two male patients with schwannoma, one of which was localized to the hard palate and the other to the facial soft tissue around the mandibular mentum and caused swelling.