Browsing by Author "Tuncer, O"

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Anal Protrusion of Ventriculo-Peritoneal Shunt Catheter in an Infant
(Elsevier Science Bv, 2003) Çaksen, H; Kiymaz, N; Odabas, D; Tuncer, O; Atas, B
Asymmetrical Nonscalp Aplasia Cutis Congenita: a Case Report
(Wiley, 2004) Atik, B; Tan, O; Bayram, I; Tuncer, O; Kirimi, E
Aplasia cutis congenita or congenital absence of the skin is a rare and serious congenital disease; its etiopathogenesis remains unclear. In this condition, localized or widespread areas of skin are absent at birth. A newborn suffering from an unusual aplasia cutis congenita located asymmetrically on the nonscalp, without blistering, was presented. This patient was completely healed with conservative treatment.
A Boy With Organophosphate Poisoning Mimicking a Foreign Body Aspiration
(Elsevier Science inc, 2005) Çaksen, H; Demirtas, M; Tuncer, O; Odabas, D; Ceylan, N; Kati, I; Köseoglu, B
A Case of Limb-Body Wall Complex Diagnosed in Utero
(Elsevier Science inc, 2003) Çaksen, H; Atas, B; Tuncer, O; Odabas, D; Dal, H
A Case of Melkersson-Rosenthal Syndrome Associated Withehlers-Danlos Syndrome
(Medecine Et Hygiene, 2002) Çaksen, H; Cesur, Y; Tombul, T; Üner, A; Kirmi, E; Tuncer, O; Odabas, D
Melkersson-Rosenthal syndrome (MRS) is characterized by the triad of recurrent facial palsy, lingua plicata, and facial edema. Herein, we report a case of MRS associated with Ehlers-Danlos syndrome due to rare presentation. To the best of our knowledge only one case of MRS associated with Ehlers-Danlos syndrome has been reported in the literature until now.
A Case of Thanatophoric Dysplasia Type I Associated With Mandibular Clefting
(Medecine Et Hygiene, 2004) Tuncer, O; Çaksen, H; Kirimi, E; Kayan, M; Atas, B; Odabas, D
A Case of Typhoid Fever Associated With Hemophagocytic Syndrome
(Elsevier Science inc, 2003) Çaksen, H; Akbayram, S; Öner, AF; Kösem, M; Tuncer, O; Atas, B; Odabas, D
Clinical Value of Color Doppler Ultrasonography Measurements of Full-Term Newborns With Perinatal Asphyxia and Hypoxic Ischemic Encephalopathy in the First 12 Hours of Life and Long-Term Prognosis
(Tohoku Univ Medical Press, 2002) Kirimi, E; Tuncer, O; Atas, B; Sakarya, ME; Ceylan, A
The cerebral blood flow velocities (CBFV) of infants with perinatal asphyxia and hypoxic ischemic encephalopathy (HIE) in the first 12 hours of their lives have been the chief focus of our concern in this study. Cerebral ischemia which can develop in the earlier hours of HIE, and the detection and diagnosis of this condition with color Doppler ultrasonography (cD-USG) will be put into discussion. Twenty-three full-term newborn infants who had perinatal asphyxia and HIE together with a control group constituting twenty full-term newborn infants who produced no problems, were included in our study, All of the infants underwent cD-USG in the postpartum period of the first 12 hours (mean 8.4 hours). Measurements being based upon peak systolic velocity (PSV), end diastolic velocity (EDV) and Pouecelout's resistive index (RI) in anterior and middle cerebral arteries were conducted. The infants, having been discharged from the unit they were followed up for mean 9.8 months in the outpatient clinic. PSV and EDV counts in the postpartum first 12 hours of 23 infants who were detected to have HIE were found to be significantly lower compared to the control group, whereas RI counts were found to be significantly higher (p < 0.05). The counts obtained from the right and left cerebral arteries of the infants with HIE were found to be corraleted with each others. The neonates in the patient group were observed to have gone through this prognosis: Three of them died, three of them had cerebral palsy, one of them had infantile spasms, and three of them had developmental retardation. When we compared the CBFV of the 10 neonates who had poor prognosis, retrospectively with the other 13 neonates who had good prognosis, PSV and EDV were found to be significantly lower and RI significantly higher (p < 0.05). In the light of the data we have obtained, cD-USCT can be considered to be a highly practical device in evaluating CBVF of the infants with HIE. A skillful detection of the decrease in cerebral blood flow which can develop in the postasphyxial first 12 hours and the prospective treatments being based upon this approach would contribute to the diagnosis, treatment and. prognosis of such cases. - Doppler; neonatal; cerebral blood flow velocities (C) 2002 Tohoku University Medical Press.
Congenital Cytomegalovirus Infection Associated With Anomalies of the Left Foot
(Medecine Et Hygiene, 2005) Ceylan, A; Tuncer, O; Akbayram, S; Çaksen, H; Dogan, M; Gülmehmed, F; Kirimi, E
Cranial Mri Findings in Children With Protein Energy Malnutrition
(Taylor & Francis Ltd, 2005) Odabas, D; Çaksen, H; Sar, F; Ünal, O; Tuncer, O; Atas, B; Yilmaz, C
In this study, cranial magnetic resonance imaging (MRI) findings were investigated in children with moderate and severe protein energy malnutrition (PEM) to determine cerebral abnormalities in malnutrition in childhood. A total of 20 children aged 3 months to 36 months were included in the study. Thirteen (65%) children had severe malnutrition and seven (35%) children had moderate malnutrition. Fifteen (75%) children had abnormal MRI findings: all of them had cerebral atrophy, and 10 (75%) children had cerebral atrophy plus ventricular dilatation. None of the children had abnormality in the brain stem or cerebellum. The authors did not find statistically significant differences between the groups when comparing the MRI findings for degree of malnutrition, head circumference, iron deficiency anemia, and serum albumin levels. In conclusion, the findings showed that most (75%) children with moderate/severe PEM had abnormal MRI findings. Therefore, it is suggested that children with PEM should be evaluated for cerebral atrophy.
Cutaneous Anthrax in Eastern Turkey
(Excerpta Medica inc, 2001) Çaksen, H; Arabaci, F; Abuhandan, M; Tuncer, O; Cesur, Y
Anthrax, caused by the spore-forming bacterium Bacillus anthracis, is rarely seen in industrial nations but is common in developing countries. Cutaneous anthrax (CA), the most common form of the disease, accounts for 95% of cases and usually develops on exposed sites. This study reviews the clinical and laboratory findings of 21 patients diagnosed with CA during 2 separate epidemics in the Van region of Turkey. All patients had a history of direct contact with infected cattle. The patients, aged 1.5 to 64 years, included 13 females and 8 mates. Of the patients, 9 were 15 years or younger. Skin lesions were localized on the hands and fingers in 15 patients, on the face in 3 patients, on the face and finger in 1 patient, on the chest and-finger in 1 patient, and on the eyelid in 1 patient. Gram-positive bacillus were noted on Gram-stains of material obtained from skin lesions in 2 patients. All but one patient was successfully treated with penicillin; the unresponsive patient was treated with cefuroxime and required plastic reconstructive surgery because of a skin defect on the eyelid.
Do Not Overlook Acute Isoniazid Poisoning in Children With Status Epilepticus
(B C decker inc, 2003) Çaksen, H; Odabas, D; Erol, M; Anlar, Ö; Tuncer, O; Atas, B
A previously healthy 2-year-old girl was admitted with generalized convulsive status epilepticus. She was in a stupor and could respond only to painful stimuli. She also had severe metabolic acidosis. Although initial liver function tests were nor-Mal, they were found to be moderately high on the fifth day of admission; however, they dropped to their normal ranges on the twelfth day of admission. Initially, the patient was diagnosed as having idiopathic status epilepticus, and classic anticonvulsant agents, including diazepam, phenytoin, and then phenobarbital, were given. However, her seizures did not subside, and diazepam infusion was initiated. After initiation of diazepam infusion, the seizures were completely controlled. On the fourth day of admission, her parents said that she had accidentally received 20 tablets (a total dose of 2000 mg) of isoniazid just before admission to our hospital. Later, we injected 200 mg of pyridoxine intravenously. During follow-up, her general condition improved, and anticonvulsant agents were discontinued because an electroencephalogram was found to be normal. She was discharged from the hospital on the twelfth day of admission. At the fourth month of follow-up, she was seizure free. Because of this case, we would like to re-emphasize that acute isoniazid poisoning should also be considered in a child with unexplained status epilepticus.
The Effects of Prednisolone and Serum Malondialdehyde Levels in Puppies With Experimentally Induced Meconium Aspiration Syndrome
(Sage Publications Ltd, 2003) Kirimi, E; Tuncer, O; Kösem, M; Ceylan, E; Tas, A; Tasal, I; Caksen, H
The aim of this study was to investigate the effect of different doses of prednisolone in puppies experimentally induced with meconium aspiration syndrome (MAS). Meconium was collected from human babies in the first day of life and was released into the trachea of 11 newborn puppies to induce MAS. Puppies were treated with 2 mg/kg prednisolone (standard dose), 30 mg/kg prednisolone (megadose) or 0.9% saline, all administered intravenously. The study ended 20 h after meconium aspiration and the lungs were then scored for histopathology. Animals not treated with prednisolone deteriorated after 8 h while respiration rate, oxygenation, pH and partial pressure of carbon dioxide values were better in the prednisolone-treated groups. Histopathology scores were better in the treatment groups compared with the control group, with megadose giving the best result. At the end of the study, serum malondialdehyde levels were significantly higher in the megadose prednisolone group compared with the other two groups. In conclusion, we determined that prednisolone reduced physiological and histological changes in puppies with MAS and that a 30 mg/kg dose was more effective than 2 mg/kg.
Evaluation of Thyroid and Parathyroid Functions in Children Receiving Long-Term Carbamazepine Therapy
(Taylor & Francis Ltd, 2003) Çaksen, H; Dülger, H; Cesur, Y; Atas, B; Tuncer, O; Odabas, D
We studied serum calcium, phosphorus, alkaline phosphatase (ALP), thyroid hormones (total thyroxine [TT4], free thyroxine [FT4], thyroid-stimulating hormone [TSH]), parathyroid hormone (PH), and osteocalcine levels in children with epilepsy who had been receiving long-term carbamazepine (CBZ) therapy to determine whether there was any effect of CBZ therapy on these hormones. The study included 18 patients with epilepsy receiving CBZ and 16 healthy age-matched controls. The age ranged from 4-18 years (11.26 +/- 3.59 years) and 4.5-17 years (11.16 +/- 3.13 years) in the study and control group, respectively. The duration of CBZ use was between 10 months-5 years (3.12 +/- 1.09 years). When comparing the results we did not find any significant difference in serum calcium, phosphorus, ALP, osteocalcine and TSH and PH levels between the groups (p > .05). However, serum TT4 and FT4 levels were found to be significantly lower in the study group than those of control group (p < .05). However, we observed no clinical signs of hypothyroidism in all subjects. To these findings we suggest that serum thyroid hormone levels should be monitored in children receiving long-term CBZ therapy.
Four Children With Colchicine Poisoning
(Arnold, Hodder Headline Plc, 2004) Atas, B; Çaksen, H; Tuncer, O; Kirimi, E; Akgün, C; Odabas, D
Colchicine poisoning is a rare event. It is characterized by multiorgan involvement and by poor prognosis associated with overdose. In this article we present four children with colchicine poisoning to emphasize that colchicine poisoning has a large spectrum in childhood. The children's ages ranged between 1 year and 3.5 years. The ingested dosage of colchicine was between 0.37 and 1.72 mg/kg. Most of the findings of colchicine poisoning such as gastrointestinal symptoms, hepatotoxicity, cardiotoxicity, bone marrow suppression, hypocalcaemia and hair loss were diagnosed in our patients. Two children receiving 0.37 mgukg and 1 mg/kg colchicine and admitted 13 and 19 hours after poisoning, respectively, died. Our findings suggest that in addition to amounts of the drug, mortality was also related to the duration between drug ingestion and admission to hospital.
A Girl With a Giant Bladder Stone
(Elsevier Science inc, 2004) Atas, B; Caksen, H; Arslan, S; Akbayram, S; Kirimi, E; Tuncer, O; Kayan, M
Hyperkalemia Most Likely Associated With Massive Cephalhematoma in a Newborn Infant Who Was Treated With Urgent Peritoneal Dialysis: Case Report
(Elsevier Science inc, 2003) Kirimi, E; Tuncer, O; Atlas, B; Arslan, S
Cephalhematomas rarely lead to serious complications such as infection, osteomyelitis and skull fractures. However, we present a newborn infant with hyperkalemia in the context of a serious complication believed to be caused by hemolysis of a large cephalhematoma. The patient was treated with urgent peritoneal dialysis and discharged with a successful outcome. In conclusion, neonates with massive cephalhematoma should be closely examined in terms of bilirubin counts as well as electrolyte counts. (C) 2003 Elsevier Science Inc.
Isolated Left Oculomotor Nerve Palsy Following Measles
(B C decker inc, 2002) Çaksen, H; Acar, N; Odabas, D; Çakin, C; Tuncer, O; Atas, B
A 10-month-old boy was admitted with ptosis on the left eyelid, which rapidly occurred following a disease with rash about 20 days before admission to our hospital. By history, none of the vaccinations had been performed. On physical examination, his vital signs were stable, and he had marasmus. Isolated left oculomotor nerve palsy was diagnosed. Cranial magnetic resonance imaging was normal. Serum IgM antibody to measles virus was positive. Oculomotor nerve palsy markedly improved on the 15th day of follow-up, and complete improvement was noted on the second month of follow-up. To our knowledge, this is the first case of oculomotor nerve palsy following measles.
Myoglobinuric Renal Failure - Response
(Elsevier Science inc, 2004) Kirimi, E; Tuncer, O; Atas, B; Arslan, S; Ataş, B.; Arslan, S.
No Effect of Long-Term Valproate Therapy on Thyroid and Parathyroid Functions in Children
(Taylor & Francis Ltd, 2002) Çaksen, H; Dülger, H; Cesur, Y; Odabas, D; Tuncer, O; Atas, B
In this study, we studied serum calcium, phosphorus, alkaline phosphatase, thyroid hormones (total thyroxine, free thyroxine, thyroid-stimulating hormone), parathyroid hormone, and osteocalcine levels in children with epilepsy who had been receiving long-term valproate (VPA) therapy in order to determine whether there was any effect of VPA therapy on these hormones. The study included 31 patients with epilepsy receiving VPA and 22 healthy age-matched controls. The age ranged from 15 months to 16 years and 18 months to 17 years in the study and control group, respectively. The duration of VPA use was between 12 months and 5 years (1.93 +/- 1.90 years). When comparing the results, we did not find any significant difference in any of the parameters, including serum calcium, phosphorus, alkaline phosphatase, osteocalcine, and thyroid and parathyroid hormone levels, between the study and control group. We suggest that VPA can safely be used with regard to thyroid and parathyroid dysfunction in childhood epilepsy.