YYÜ GCRIS Basic veritabanının içerik oluşturulması ve kurulumu Research Ecosystems (https://www.researchecosystems.com) tarafından devam etmektedir. Bu süreçte gördüğünüz verilerde eksikler olabilir.

Browsing by Author "Umaz, Adil"

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    Determination and Comparison of Metal Contents in Simulated Body Fluid Medium Conditions of the Plant Species by Flame Atomic Absorption Spectrometry (Faas)
    (Marmara Univ, 2022) Umaz, Adil; Aydin, Firat; Tokul Olmez, Ozge; Firat, Mehmet; Ozturk, Mehmet; Ertas, Abdulselam; Aydin, Isil
    The importance of plants in folk medicine and scientific studies is increasing day by day. In this context, the plants pose a danger to human health when they are eaten by the public, consumed as herbal tea or used as medicinal plants especially the toxic metals in their composition. For this reason, determining the macro, micro and toxic element content in the plants is important for health. In this study; the metal contents of root and aerial parts of nine different Salvia species were determined and the chemometric evaluation of the obtained results was made. In the principal component analysis (PCA) made with 20 elements of Salvia species, it was determined that the first two principal components explained 62.60% of the variance and the first six principal components explained 92.70%. When PCA and hierarchical cluster analysis (HCA) results are evaluated; the parts of Salvia species root and aerial parts were determined that were not clearly separated and there was no regional grouping. In addition, Salvia species prepared as herbal tea was left to different simulated body fluid medium conditions, and the changes in metal contents were examined. It was determined that were taken up Cr, Cd, Pb, Cu, Zn metals in the simulated saliva fluid (SSF), Ni, Mn metals in the simulated gastric fluid (SGF), and Na, K metals in the simulated intestinal fluid (SIF). It was determined that Fe metal in almost all Salvia species was not taken from three simulated body fluid mediums. Thus, elements determined which were taken up in body fluid mediums.
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    Farklı Familyalara Ait Türlerdeki Element Analizlerinin İndüktif Eşleşmiş Plazma Kütle Spektrometrisi (Icp-ms) ile Belirlenmesi ve Karşılaştırılması
    (2022) Umaz, Adil; Fırat, Mehmet; Aydin, Firat; Ertaş, Abdulselam
    Bitkilerin tüketimi ve tıbbi amaçlı kullanımları her geçen gün artmaktadır. Bu nedenle bitki içeriklerinin bilinmesi insan sağlığı açısından önemlidir. Bu çalışmada dört farklı familyaya ait on dokuz türün çoklu element içerikleri belirlenmiştir. Bu familyalara ait aynı cinsin farklı türlerinin çoklu element içerikleri karşılaştırılmıştır. Ayrıca, aynı cinsin farklı kısımlarının element içerikleri karşılaştırılmıştır. Aynı cinsin farklı türlerinin ve aynı türün farklı kısımlarının element içerikleri birbirinden farklı olduğu tespit edilmiştir. Ayrıca, türlerin Cd ve Pb içerik sonuçları Dünya Sağlık Örgütü'nün (WHO) ham bitki materyalinde izin verilen maksimum konsantrasyon değerleri ile karşılaştırılmıştır. Tüm türlerde Cd içeriği WHO tarafından belirlenen değerden yüksek bulunmuştur. Yalnızca, Sternbergia clusiana Boiss'in Pb içeriği. (A3) WHO tarafından tespit edilen değerden daha yüksek olduğu tespit edildi.
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    An Investigation and Comparison of Concentration Change in Simulated Body Fluid Medium Conditions of the Calcium Element in 27 Different Salvia Species
    (Istanbul Univ, Fac Pharmacy, 2023) Umaz, Adil; Aydin, Firat; Firat, Mehmet; Yener, Ismail; Ertas, Abdulselam; Elmastas, Ayhan
    Background and Aims: In this study, calcium (Ca) element concentration changes of Salvia species in simulated body fluid (SBF) medium conditions were investigated and the results in these medium conditions were compared with each other.Methods: Salvia species samples were air-dried and ground into powder. Salvia species was prepared as a herbal tea. Pre-pared teas were left in three different SBF medium conditions. The samples were analyzed using Flame Atomic Absorption Spectroscopy (FAAS) method to determine the Ca absorptions. Also, a correlation analysis of the results obtained in three different SBF medium conditions and the species in simulated gastric fluid (SGF) medium conditions was performed.Results: When the SBF medium conditions were compared, it was determined that the highest Ca absorption of all Salvia species occurred in the SGF conditions. Thus, it can be said that the Ca in plants and foods occurs in the gastric fluid medium and its absorption occurs there. When the result of the correlation analysis was evaluated, it was determined that there was a stronger correlation between the SGF and simulated intestinal fluid (SIF) mediums compared to other mediums.Conclusion: The Ca absorption was determined according to what remained in the SGF the most. Based on the results ob-tained from SBF medium conditions, it can be said which element is taken in which body fluid medium. Information on the differences between samples belonging to different SBF medium conditions was not obtained. However, when the simulated fluid medium conditions were evaluated individually, information was obtained for two or more samples.