Browsing by Author "Ustun, Yusuf"

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Are Serum Lipid Levels Associated With Depression in Hemodialysis Patients
(Turk Nefroloji Diyaliz Transplantasyon dergisi, 2006) Sahin, Idris; Kiran, Umit Kemal; Sahin, Huseyin Avni; Ustun, Yusuf; Agargun, Mehmet Yucel; Erkoc, Reha
Background: Recent study suggested a relation between low levels of serum lipids and depression. The aim of this study was to assess the association between serum lipid levels and depression in patients with end-stage renal disease (ESRD). Methods: All the patients who were attending Yuzuncu Yil University Faculty of Medicine Training Hospital Hemodialysis Unit, in Turkey, from August 2000 to July 2001, were prospectively studied. Serum TC, LDL-c, HDL-c, VLDL-c and triglyceride levels were measured and Beck Depression Inventory (BDI) was administered to all patients. Diabetic patients were excluded. Results: There were 46 patients (25 males and 21 females). Mean duration of hemodialysis was 28.1 +/- 30.2 months. Mean Kt/V was 1.2 +/- 0.4. The mean age of study group was 45.2 +/- 16.3 years and the age range was 15-73 years. Mean serum albumin concentration was 3.63 +/- 0.55 (2.5-4.7) g/dL. The patients' mean BDI was 15.9 +/- 6.2 (431). There was association between serum TC (total cholesterol), LDL-c (low density lipoprotein cholesterol), HDL-c (high density lipoprotein cholesterol) and depression but no association between serum VLDL-c (very-low density lipoprotein cholesterol) and triglyceride levels and depression in patients with ESRD. Conclusion: Depression is the most common psychological finding in patients with ESRD. Our study demonstrate that there were associations between low serum TC, LDL-c, HDL-c levels and depression but there was no association between depression and serum triglyceride and VLDL-c levels in patients with ESRD.
A Case of Transverse Vaginal Septum Diagnosed During Labor
(Aves, 2005) Ustun, Yusuf; Ustun, Yaprak Engin; Zeteroglu, Sahin; Sahin, Guler; Kamaci, Mansur
Transverse vaginal septum is the result offliulty canalization of the embryonic vagina. We described a case of transverse vaginal septum with a small central aperture diagnosed during labor. An 18-years-old girl at 28 weeks of gestation presented to our obstetric department complaining of symptoms of preterm delivery. Pelvic and vaginal ultrasonography, with gynecologic examination established a diagnosis of transverse vaginal septum in mid vagina. An incision in the vaginal septum allowed us to see the head of the fetus in the vagina. The diagnosis of transverse vaginal septum was confirmed during labor and excision of the septum prevented the uterine rupture.
A Prospective Randomized Study Comparing Misoprostol and Oxytocin for Premature Rupture of Membranes at Term
(Taylor & Francis Ltd, 2006) Zeteroglu, Sahin; Engin-Ustun, Yaprak; Ustun, Yusuf; Guvercinci, Mehmet; Sahin, Guler; Kamaci, Mansur
Objective. The aim of this randomized trial was to compare the efficacy and safety of vaginal misoprostol and oxytocin for cervical ripening and labor induction in patients with premature rupture of membrane ( PROM) at term. Methods. Ninety-seven women with PROM at term were assigned randomly to receive intravaginal misoprostol or oxytocin. The primary outcome measure was the induction - delivery interval. Secondary outcomes included the number of women who delivered vaginally within 12 hours of the start of the induction in the two groups, the cesarean, hyperstimulation, and failed induction rates, the mode of delivery, and the neonatal outcome. Results. Forty-eight women were assigned to intravaginal misoprostol and 49 to oxytocin administration. The mean interval from induction to delivery was 10.61 +/- 2.45 hours in the misoprostol group and 11.57 +/- 1.91 hours in the oxytocin group ( p = 0.063). The rates of vaginal delivery were 83.3% and 87.7% and cesarean delivery were 16.7% and 8.2% in the misoprostol and oxytocin groups, respectively. Neonatal outcomes were not significantly different. Of the cases, 8.3% in the misoprostol group and 8.2% in the oxytocin group revealed uterine contraction abnormalities. Conclusion. Our study demonstrates that, intravaginally, misoprostol results in a similar interval from induction of labor to delivery when compared to oxytocin.
Umbilical Artery Erythropoietin Levels in Preeclamptic Pregnancies
(Galenos Yayincilik, 2006) Sahin, H. Guler; Surucu, Ramazan; Zeteroglu, Fiahin; Ustun, Y. Engin; Ustun, Yusuf; Kamaci, Mansur; Kolusari, Ali
Objective: The aim of this study was to determine the levels of umbilical artery erythropoietin (EPO) levels and to evaluate its relation with clinical findings. Material and Methods: In this prospective study, 26 normal (Group I), 25 mild preeclamptic (Group II) and 17 severe preeclamptic (Group III) pregnant women whose gestational ages were between 37-42 weeks were enrolled. After the delivery, blood samples were taken from the umbilical artery of double clamped umbilical cord and umbilical artery EPO levels and blood gas parameters were analyzed. Sociodemographic findings, labor properties and physical examination of neonates were recorded. The blood gas parameters, EPO levels, their relationships with clinical findings of the groups were evaluated. Statistical analyses were performed by SPSS 9.05 statistical package program. Results: There were no statistical differences between gravidity, parity and gestational ages of the groups (p> 0.05). Maternal ages were significantly higher in the second group when compared with the others (p< 0.05). Systolic and diastolic blood pressures were statistically different in the groups (p< 0.05), and the highest levels were found in the third group. Birth weights were; 3480.76 +/- 431.75, 3373.20 +/- 846.83 and 2497.05 +/- 859.83 grams in group I, group II and group III, respectively (p< 0.05). First minute Apgar scores were 8 (ranges between 7-10) in the first group, 8 (ranges between 3-9) in the second group and 6 (ranges between 3-9) in the third group (p< 0.05). Umbilical cord pH levels were 7.35 +/- 0.06, 7.25 +/- 0.11 and 7.19 +/- 0.09; base excess (BE) levels were -4,71 +/- 2,02, -6.53 +/- 3.98 and -9.29 +/- 3.82 mmol/L; EPO levels were 30.0 (9.2-122), 62.5 (11.0-549) and 167.4 (10.1-908) mU/ml, respectively, and the differences between the groups were statistically significant (p< 0.05). In the Spearman bivariate correlation analysis, there was no significant relation between maternal age and EPO levels. There was significant positive correlation between EPO levels and systolic, diastolic blood pressures, pCO2 levels, and, significant negative correlation between first, fifth minute Apgar scores, birth weight, umbilical cord blood pH and BE levels. Conclusions: After delivery umbilical artery EPO levels showed significant correlation with severity of preeclampsia and, clinical and biochemical determinants of perinatal hypoxia. Our results support that erythropoietin can be used as a biochemical determinant of chronic fetal hypoxia that is caused by preeclampsia.