Browsing by Author "Ustyol, L."
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Conference Object Acute Peritoneal Dialysis in Critically Ill Newborns(Springer, 2016) Ustyol, L.; Peker, E.; Demir, N.; Agengin, K.; Tuncer, O.Article A Case of Acute Disseminated Encephalomyelitis Mimicking Leukodystrophy(2010) Kaya, A.; Acikgoz, M.; Ustyol, L.; Avcu, S.; Sal, E.; Okur, M.; Caksen, H.Acute disseminated encephalomyelitis (ADEM) is a monophasic, immune-mediated demyelinating disorder that can follow immunizations or more often infections including rubeola, rubella, varicella, herpes zoster, mumps, Mycoplasma pneumoniae, or, more commonly, other nonspecific upper respiratory tract infections. Documentation of a preceding illness is not required to make this diagnosis. This report examines the case of a 9-month-old male patient presenting with the features of an acute leukodystrophy following innoculation with the mixed vaccine Pentaxim (Sanofi Pasteur, LyonFrance) while suffering from a lower respiratory tract infection, and who was eventually diagnosed as ADEM. The case is presented as a reminder that ADEM can sometimes be linked to lower respiratory tract infection and vaccination, and that the features in such cases can be confused with leukodystrophy.Article Comparative Evaluation of Ceftriaxone- and Cefotaxime-Induced Biliary Pseudolithiasis or Nephrolithiasis: a Prospective Study in 154 Children(Sage Publications Ltd, 2017) Ustyol, L.; Bulut, M. D.; Agengin, K.; Bala, K. A.; Yavuz, A.; Bora, A.; Dogan, M.Background: Biliary lithiasis, or sludge, and nephrolithiasis have been reported as a possible complication of ceftriaxone therapy. However, no study related to cefotaxime-induced biliary pseudolithiasis or nephrolithiasis was observed in the literature. Therefore, we investigated the comparative formation of biliary pseudolithiasis and nephrolithiasis after cefotaxime and ceftriaxone therapies. Methods: The patients treated with ceftriaxone or cefotaxime were enrolled during the study period. Ultrasound imaging of the biliary and urinary tract was performed in all patients before and after the treatment. The patients with a positive sonographic finding at the end of treatment were followed up with monthly ultrasonography for 3 months. Results: The present study showed that abnormal biliary sonographic findings were demonstrated in 18 children (20.9%) treated with ceftriaxone, 13 (15.1%) had biliary lithiasis, 5 (5.8%) had biliary sludge and 1 (1.2%) had nephrolithiasis. Abnormal biliary sonographic findings were demonstrated in only four (5.9%) children treated with cefotaxime who had biliary sludge and only one (1.5%) had nephrolithiasis. It was observed that older age was at significantly higher risk of developing biliary sludge or stone formation. Receiver operating characteristic analysis was performed to determine the residual risk and analysis found that 4.5 years was the cut-off value for age. Conclusions: The present study is unique in the literature for reporting for the first time gall bladder sludge and nephrolithiasis associated with cefotaxime use. Therefore, patients treated with cefotaxime should be monitored for serious complications like patients treated with ceftriaxone. Nevertheless, if third-generation cephalosporin is used, cefotaxime is recommended to be used rather than ceftriaxone.Article Determination of Underlying Causes in Asymptomatic, Earlystage Renal Diseases by Dipstick Test(Medical Association of Zenica-Doboj Canton, 2013) Okur, M.; Arslan, S.; Guven, A.S.; Temel, H.; Bektas, M.S.; Ustyol, L.Aim To prevent possible chronic kidney diseases in healthy school- age children by screening for hematuria and proteinuria using a urine strip. Methods The incidence of hematuria and proteinuria was determined in 1848 healthy school-age children aged 7 to 14 years by urine screening in the eastern region of Turkey in 2008. Cases with persistent hematuria and/or proteinuria were referred to a pediatric nephrologist, and further examinations were carried out. Results Isolated hematuria, isolated proteinuria, and combined hematuria-proteinuria were found in 92 (4.9%), 16 (0.8%) and 10 (0.5%) patients, respectively. In addition, 11.9% (11/92) of cases of isolated hematuria and 40% (4/10) of cases of combined hematuria- proteinuria were observed to have persisted. Persistent hematuria and persistent hematuria-proteinuria were found in 11 (0.5%) and 4 (0.2%) patients, respectively. In these cases, underlying causes were found: renal stone disease, hypercalciuria, urinary tract infection, vesicoureteral relux, atrophic kidney, and IgA nephropathy. Conclusion According to this study, cases with persistent hematuria should be examined especially in terms of renal stones, hypercalciuria, and urinary tract infection.Article Ewing's Sarcoma Localized in the Mandible: a Case Report(Univ West indies Faculty Medical Sciences, 2015) Akbayram, S.; Basaranoglu, M.; Kaya, A.; Acikgoz, M.; Ustyol, L.; Taskin, G. A.; Dogan, M.Ewing's sarcoma is one of the most aggressive primary bone tumours. Ewing's sarcoma arising from the bones of the head and neck region is extremely rare; only 4-9% of all Ewing's sarcoma originate in this region. We report a case of Ewing's sarcoma localized in the mandible because of its unusual presentation.Article Impact of Patent Ductus Arteriosus and Subsequent Therapy With Ibuprofen on the Release of S-100b and Oxidative Stress Index in Preterm Infants(International Scientific Literature Inc., 2014) Demir, N.; Ece, İ.; Peker, E.; Kaba, S.; Ustyol, L.; Balahoroğlu, R.; Tuncer, O.Background: Hemodynamically significant patent ductus arteriosus (hsPDA) leads to injury in tissues/organs by reducing perfusion of organs and causing oxidative stress. The purpose of this study was to evaluate the oxidant/antioxidant status in preterm infants with hsPDA by measuring the total antioxidant capacity and total oxidant status and to assess neuronal damage due to oxidant stress related to hsPDA.; Material/Methods: This prospective study included 37 low-birth-weight infants with echocardiographically diagnosed hsPDA treated with oral ibuprofen and a control group of 40 infants without PDA. Blood samples were taken from all infants, and than the total antioxidant capacity (TAC), total oxidant status (TOS), and S-100B protein levels were assessed and oxidative stress index was calculated before and after therapy.; Results: The mean pre-therapy TOS level and oxidative stress index (OSI) value of the patients with hsPDA were significantly higher, but TAC level was lower than in the control group. There were no statistically significant differences in the mean post-therapy values of TOS, TAC, OSI, and S-100B protein between the two groups.; Conclusions: hsPDA may cause cellular injury by increasing oxidative stress and damaging tissue perfusion; however the brain can compensate for oxidative stress and impaired tissue perfusion through well-developed autoregulation systems to decrease tissue injury. © Med Sci Monit 2014.Article Infantile Digital Fibromatosis (Inclusion Body Fibromatosis) Observed in a Baby Without Finger Involvement(2013) Kaya, A.; Yuca, S.A.; Karaman, K.; Erten, R.; Dogan, M.; Bektas, M.S.; Ustyol, L.A 9-day-old male baby was hospitalized after his birth due to some swells under the skin. The hard consistency nodules observed under the skin all over the body of the patient were of different size, and presented lesions, among which the biggest was 1 × 1 cm. No lesions were observed on the fingers. By superficial ultrasonography, multiple isoechoic hypoechoic lesions were observed among the muscle plan. In thoracolumbar magnetic resonance imaging, multiple massif lesions retaining peripheral contrast (the biggest was 1.7 × 1.4 cm large) had been observed under the skin muscle plans, between the muscles of the extremities. The biopsy was positive for smooth muscle actin, but negative for desmin, S100, and CD34. These findings were diagnosed as infantile digital fibromatosis (IDF) (inclusion body fibromatosis). The case was presented with an objective to illustrate and remind that IDF can be observed in babies without finger involvement.Letter Joubert Syndrome Associated With Patent Ductus Arteriosus in a Newborn Infant(Medecine Et Hygiene, 2009) Peker, E.; Kirimi, E.; Sal, E.; Ceylan, A.; Ustyol, L.; Caksen, H.Conference Object The Levels of Vitamin B12, Folate, and Homocysteine in a Population With High Prevalence of Neural Tube Defects(Springer, 2016) Peker, E.; Demir, N.; Tuncer, O.; Ustyol, L.; Balaharoglu, R.; Kaba, S.; Karaman, K.Conference Object The Screening of Hematuria and Proteinuria in School-Age Children(Wiley-blackwell, 2011) Okur, M.; Arslan, S.; Guven, A. S.; Temel, H.; Bektas, Ms; Ustyol, L.