Browsing by Author "Vasseghian, Yasser"

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Facile Bio-Fabrication of Pd-Ag Bimetallic Nanoparticles and Its Performance in Catalytic and Pharmaceutical Applications: Hydrogen Production and In-Vitro Antibacterial, Anticancer Activities, and Model Development
(Elsevier, 2022) Gulbagca, Fulya; Aygun, Aysenur; Altuner, Elif Esra; Bekmezci, Muhammed; Gur, Tugba; Sen, Fatih; Vasseghian, Yasser
The production of nanoparticles by the biosynthesis method attracts great attention due to their environmentally friendly structure and biocompatibility. In this study, a green method for the synthesis of Palladium-Silver nanoparticles (Pd-Ag NPs) using the extract of Nigella satioa seeds is reported. Pd-Ag NPs obtained by the green synthesis method were characterized by transmission electron microscopy (TEM), atomic force microscopy (AFM), UV-vis spectrometry, and X-Ray diffraction patterns (XRD). Pd-Ag NPs were seen to have a spherical structure in the TEM analysis image and the average particle size was found to be 6.80 nm. In addition, the anticancer and antibacterial activities of Pd-Ag NPs synthesized by the green synthesis method were investigated. Pd-Ag NPs had lethality of 69.26%, 52.28%, 76.90%, and 57.49% respectively, against Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus, Bacillus subtilis, and Escherichia coli bacteria at 200 mu g/mL. Besides, the antibacterial activity of Pd-Ag NPs against B. subtilis, S. aureus, and MRSA bacteria was developed by the Neuro-fuzzy (ANFIS) model. The minimum inhibitory concentration (IC50) values of Pd-Ag NPs against human breast cancer cells, human endometrial carcinoma cells, and human cervical cancer cell lines were determined as 12.4384 +/- 0.39 mu g/mL, 13.5043 +/- 0.539 mu g/mL, 17.7172 +/- 0.782 mu g/mL, respectively. The catalytic activity of Pd-Ag NPs was investigated by sodium borohydride (NaBH4) hydrolysis. Enthalpy, entropy, turner of frequency (TOF), and activation energy values were calculated as 24.51 kJ/mol, -183.15 J/mol.K, 1387.29 h(-1), 27.01 kJ/mol, respectively. In the light of the obtained results, it promises that Pd-Ag NPs may play a therapeutic role in complications related to cancer and bacterial infections. The use of Pd-Ag NPs as catalysts will contribute to the development and application of new nano-catalysts to reduce environmental pollution. (C) 2022 Institution of Chemical Engineers. Published by Elsevier Ltd. All rights reserved.
Facile Synthesis of Biogenic Palladium Nanoparticles Using Biomass Strategy and Application as Photocatalyst Degradation for Textile Dye Pollutants and Their In-Vitro Antimicrobial Activity
(Pergamon-elsevier Science Ltd, 2022) Liang, Yunyi; Demir, Halit; Wu, Yingji; Aygun, Aysenur; Tiri, Rima Nour Elhouda; Gur, Tugba; Vasseghian, Yasser
Among biological applications, plant-mediated Pd NPs for multi-drug resistance (MDR) developed in pathogenic bacteria were synthesized with the help of biomass of lemon peel, a biological material, with a non-toxic, environmentally friendly, human-nature green synthesis method. Characterization of synthesized Pd NPs was carried out by UV-Vis spectrometry, Transmissive Electron Microscopy (TEM), X-ray diffraction (XRD), and
Phyto-Mediated Synthesis of Nanoparticles and Their Applications on Hydrogen Generation on Nabh4, Biological Activities and Photodegradation on Azo Dyes: Development of Machine Learning Model
(Pergamon-elsevier Science Ltd, 2022) Lin, Junqing; Gulbagca, Fulya; Aygun, Aysenur; Tiri, Rima Nour Elhouda; Xia, Changlei; Van Le, Quyet; Vasseghian, Yasser
This work reports the synthesis of the silver-platinum bimetallic nanoparticles (N@Pt-Ag BNPs) reduced by an ethanolic extract of black seed (Nigella sativa, N) using the green synthesis method, these nanoparticles show a great antibacterial, anticancer, and catalytic activity. The characterization of physicochemical properties of AgPt BNP was carried out using UV-visible spectroscopy (Uv-vis), Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and Transmission electron microscope (TEM) analysis. The structural morphology shows that the N@Pt-Ag BNPs are spherical particles with a diameter of 5.6 nm. The cytotoxic effects of N@Pt-Ag BNPs were examined by MTT test in human breast cancer, human colon cancer, human pancreatic cancer, L929Murine fibroblast cells. N@Pt-Ag BNPs have been observed to be much more effective in breast cancer cell lines. The cytotoxic effect of N@Pt-Ag BNPs against healthy L929-murine fibroblast cell lines was not observed. Also, high antibacterial activity on each of the bacteria Escherichia coli (E. coli), Bacillus subtilis (B. subtilis), Methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus aureus (S. aureus), where we note that most strains of E. coli and S. aureus were damaged with a 73% percentage, 67% bacterial inhibition respectively. The results of the catalytic activities of N@Pt-Ag BNPs were obtained by performing the hydrolysis experiments of sodium borohydride (NaBH4). According to the results obtained, TOF, enthalpy, entropy, and activation energy, values were found to be 2497.14 h(-1), 13.52 kJ/mol,-137.47 J/mol.K, 16.02 kJ/mol, respectively. N@Pt-Ag BNPs were found to be highly effective catalysts for hydrogen production which this was also confirmed by the machine learning model. The photocatalytic activity of N@Pt-Ag BNPs was tested against methylene blue (MB) dye and the highest activity was found as 80%.