Browsing by Author "Yüksel, H"
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Article Dicephalus, Arnold-Chiari Malformation, Spinal Dysraphism and Other Associated Anomalies in a Newborn Holstein Calf(Tubitak Scientific & Technological Research Council Turkey, 2005) Gülbahar, MY; Yüksel, H; Soygüder, Z; Erçin, ÖFA case of dicephalus, Arnold-Chiari malformation, spinal dysraphism and other associated defects was described in a newborn Holstein calf. The heads were medially and caudally joined with temporal bones and one common flattened occipital bone respectively. Cranial cavities became narrow dorsoventrally and included elongation of the compressed brains, and caudal displacement and hypoplasia of cerebelli. In the spinal column. variable degrees of dysraphism such as cervico-thoracal diplomyelia with hydromyelia and syringomyelia, lumbar spina bifida with spinal cord agenesis in the region were observed. The calf had also arthrogryposis of hind limbs and cleft palate of both heads.Article The Effects of Sildenafil Citrate (Viagra) in the Early Phase of Healing Process in Open Wounds in Dogs(Vysoka Skola veterinarni Farmaceuticka, 2003) Tas, A; Atasoy, N; Özbek, H; Aslan, L; Yüksel, H; Ceylan, E; Dagoglu, GIn vivo (n = 16) and in vitro (n = 16) experiments were conducted in dogs to describe the effects of sildenafil citrate (viagra) on histopathological changes during the healing process with respect to angiogenesis and compare vasodilatative effects of sildenafil citrate, acetylcholine and sodium nitroprusside. General anaesthesia was performed with 0.2% ketamine HCl by intravenous drip after premedication with xylazine (5 mg.kg(-1)) and atropine sulphate (0.05 mg.kg(-1)). Round open wounds were created in all skin layers on anterior brachial region in all animals. On days 1, 3, 5 and 7 following the operation sildenafil citrate (25 mg) (n = 8) and saline (n = 8) were orally administered. Wound tissues were dissected for histological observation on days 3, 6, and 9. Animals receiving sildenafil citrate had greater granulosa tissue more apparent capillary network and greather fibroblast proliferation than control group on day 6. Vasorelaxant effects of sildenafil citrate, acetylcholine and sodium nitroprusside on a. brachialis were investigated in vitro. In this study, relative vasorelaxant effects of sildenafil citrate, acetylcholine and sodium nitroprusside were 4.91, 5.75 and 6.70, respectively. Results of this study suggest that sildenafil citrate does enhance the healing process by stimulating angiogenesis.Article Leiomyoma of the Urinary Bladder in a Goat(Australian veterinary Assn, 2001) Timurkaan, N; Yener, Z; Yüksel, H