Browsing by Author "Yürektürk, Ş."
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Article Evaluation of Clinical and Laboratory Findings in Patients Diagnosed With Covid-19(Verduci International, 2023) Gürbüz, E.; Çelik, M.; Türkoğlu, S.; Elasan, S.; Yürektürk, Ş.; Sünnetçioğlu, M.Objective: Coronavirus disease 2019 (COVID-19) is an infectious disease that can lead to condi-tions ranging from mild upper respiratory tract infection to severe clinical manifestations, such as respiratory and multiorgan failure. Thus, this study was aimed at evaluating the clinical and laboratory findings of the patients followed up for COVID-19 in our hospital. Patients and Methods: A total of 497 patients who were older than 18 years of age and had been diagnosed with COVID-19 were included in this study. Of the 497 patients diagnosed with COV-ID-19, 57.2% were male and 42.8% were female, and the mean age was 51.59±19.95 years. While the case-death rate was 9.2%, it was 36.8% in the intensive care unit. While lung involvement was detected in 72.2% of the patients, this rate was higher in the patients followed up in the ICU (98.8%). Results: In the laboratory tests, the leukocytosis, lymphopenia, thrombocytopenia, C-reactive pro-tein, alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase, creatinine, cre-atine kinase, ferritin, procalcitonin, and D-dimer levels were higher in the deceased patients than in the surviving patients and were associated with mortality. The neutrophil/lymphocyte ratio was higher in the deceased patients when compared to the other patient groups, and it was also associated with increased mortality. Hypertension (8.6%) and diabetes mellitus (11.2%) were the most common underlying diseases in all of the patient groups. Conclusions: It was observed that the case-death rate was significantly higher in the ICU and mortality increased with advanced age. Moreover, comorbid factors were higher in patients who were followed up in the ICU and died. In the laboratory examinations, pathological findings were encoun-tered at a higher rate, especially in the patients who died. © 2023, Verduci International. All rights reserved.Article Investigation of Anti-Toxoplasma Gondii Antibodies in the Hemodialysis Patients With Elisa Method(Galenos Publishing House, 2023) Yürektürk, Ş.; Yılmaz, H.; Cengiz, Z.T.Objective: The aim of this study was to determine the seroprevalence of Toxoplasma gondii in hemodialysis (HD) patients and to reveal the importance of toxoplasmosis as a risk factor in these patients. Methods: The study was carried out between 26.12.2013 and 01.01.2016 at Van Yüzüncü University Dursun Odabaş the Medical Center on patients with chronic renal failure who entered HD. As the patient group in the study, 150 patients with chronic renal failure who underwent HD; as the control group, 50 people without any known chronic disease and who did not receive any immunosuppressive therapy were included. The ELISA method was used to determine anti-T. gondii IgG and IgM antibody levels. A questionnaire including risk factors that may cause the transmission of T. gondii was applied to the patient and control groups. Results: In the study, 89 out of total 150 HD patients (59.3%) were found anti-T. gondii IgG antibody seropositive and 4 were (2.7%) anti-T. gondii IgM antibody seropositive. Fourteen of 50 healthy individuals in the group (28%) were anti-T. gondii IgG antibody positive, while none in this group was anti-T. gondii IgM antibody positive. Statistical analysis demonstrated there were separate significant correlations between both anti-T. gondii IgG (p<0.01) and anti-T. gondii IgM antibody (p<0.05) frequencies with chronic renal failure. While there were no statistically significant differences in the prevalence of anti-T. gondii IgG antibody identification based on gender and age groups, there were significant differences between the prevalence of anti-T. gondii IgM antibody based on both gender (p<0.05) and age groups (p<0.05). Some living conditions and habits of the patient group were evaluated statistically, and a significant correlation (p<0.05) was found between eating only raw meatballs and toxoplasmosis seropositivity. Conclusion: As a result, it was understood that the physicians who monitor of HD patients should assess toxoplasmosis among the risk factors. © 2023 Turkish Society for Parasitology-Available online at www.turkiyeparazitolderg.org.Article A Parasite That Should Not Be Neglected in Patients With Ulcerative Colitis: Entamoeba Histolytica(Galenos Publishing House, 2024) Soylu, M.; Ekici, A.; Aydemir, S.; Yürektürk, Ş.; Akkaş, Ö.Objective: To determine the prevalence of amoebiasis, which has been neglected in recent years according to the World Health Organization, in ulcerative colitis patients and investigate the relationship between amoebiasis and ulcerative colitis. Methods: The study included 150 individuals, including 100 ulcerative colitis patients and 50 healthy individuals without gastrointestinal complaints. The samples collected were first analyzed macroscopically and then using native-Lugol, trichrome staining, and enzyme-linked immunosorbent assay (ELISA). Results: In the microscopic examination, Entamoeba spp. cysts were found in 22% of the ulcerative colitis patients and 2% of those in the control group. Entamoeba histolytica (E. histolytica) adhesin antigen was detected by ELISA in 31% of the ulcerative colitis patients and 4% of those in the control group. A significant correlation was found between the incidence of E. histolytica and ulcerative colitis in the statistical evaluation. Conclusion: E. histolytica should not be neglected in ulcerative colitis patients and should be investigated in the presence of diarrhea, bloody diarrhea, and abdominal pain. © 2024 Turkish Society for Parasitology.