Browsing by Author "Yasar, H."

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The Association Between Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels and Clinical Prognosis in Patients With Ischemic Stroke
(Turkish Society of Cerebrovascular Diseases, 2015) Yasar, H.; Tombul, T.; Milanlioglu, A.
Objective: Recent studies report that the insulin-like growth factor system may be involved in stroke pathogenesis, and is reported to increase myelination, maturation, cell proliferation and neuronal sprouting of the central nervous system.The aim of the present study is to demonstrate the role of insulin-like growth factor system in ischemic stroke pathogenesis and its association with the prognosis by investigating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 levels in patients diagnosed with acute ischemic stroke. MATERIAL and METHODS: Sixty-eight patients and 20 healthy individuals were included to this study. Clinical evaluation of the patients was performed according to National Institute of Health Stroke Scale and functional outcomes were graded according to Modified Rankin Scale. Bamford classification was used for the clinical classification of ischemic strokes, and the TOAST system for etiological classification. Each patient's levels of insulin-like growth factor-1 and insulin-like growth factor binding protein-3 were measured on the first, fifth and thirtieth day of ischemic stroke. RESULTS: Only the levels of insulin-like growth factor binding protein-3 on the day of 5 were significantly decreased compared to the control group. The decrease in IGF-1 values was associated with an increased risk of death and was accompanied by clinical worsening and decreased functionality. CONCLUSION: It has been concluded that the levels of investigating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 may affect mortality risk, clinical condition and functionality outcomes in patients presenting with ischemic stroke, and further studies are needed for the investigation of different effects of insulin-like growth factor- 1 in future.
Effect of Humic Acid Applications on Yield, Fruit Characteristics and Nutrient Uptake in Ercis Grape (V. Vinifera L.) Cultivar
(Chemical Publishing Co., 2006) Cangi, R.; Tarakcioglu, C.; Yasar, H.
The effects of humic acid applications on the yield, fruit characteristics and nutrient uptake of Ercis grape cultivar (V. vinifera L.) in Van in the east of Turkey were examined during two growing seasons in 2003-2004. Solid form of humic acid (55% humic acid, 30% fulvic acid and 8% K2O) were applied from soil in the amount of 100, 200, 300 kg/ha and 10, 20, 30 kg/ha from leaves. There was no significant effects of humic acid application on the yield and mean bunch weight (MBW) but there was significant effect on soluble solid contents (SSC) and total acid statistically. SSC content was increased with humic acid applications, but total acid was decreased with treatment. As a result of this study, yield, MBW, SSC total acid ranged between 6650 and 14580 kg/ha, 123.3 and 249.5 g, 12.3 and 18.0%, 1.28 and 2.05 g/L, as years and applications, respectively. In the result of leaf analysis, humic acid affected the N content (each two years), P, Fe and Zn contens of leaves (at first year), but K, Cu and Mn contents were not affected statistically. N and K content of leaves were increased with humic acid applications as compared with control. As a result, SSC, total acid, N and Fe contents of leaves of grape vines were affected by humic acid application. In cool ecology, such as Van province, increase in SSC by humic acid application will contribute to ripening of grapes before autumn frost.