Browsing by Author "Yavuz, Alparslan"

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Comparison of Placental Elasticity in Normal and Pre-Eclamptic Pregnant Women by Acoustic Radiation Force Impulse Elastosonography
(Wiley-blackwell, 2016) Karaman, Erbil; Arslan, Harun; Cetin, Orkun; Sahin, Hanim Guler; Bora, Aydin; Yavuz, Alparslan; Akbudak, Ibrahim
AimThe aim of this research was to study and compare placental elasticity with acoustic radiation force impulse (ARFI) elastography in pre-eclamptic and normal pregnancies. MethodsA total of 107 singleton pregnancies in the third trimester (38 healthy control subjects, 34 patients with gestational hypertension, and 35 pre-eclampsia patients) were included in the study. ARFI elastography was used to determine the placental elasticity in the three predetermined regions of the placenta (the fetal edge, maternal edge, and central part of the placenta). The obstetrical data regarding grayscale and Doppler ultrasonography and perinatal outcomes were reviewed. A mean placental shear wave velocity cut-off value that predicts the presence of pre-eclampsia was determined. ResultsThe shear wave elasticity values in the pre-eclampsia group in all three regions were significantly higher than in the gestational hypertension and healthy control groups (P=0.001). The most significant difference was found in the peripheral edge of the placenta from the fetal surface in the pre-eclampsia group (P=0.001). ConclusionThe stiffness of the placenta determined by the ARFI technique is significantly higher in pre-eclampsia patients. ARFI elastography of the placenta might be used as a non-invasive and easy method in the diagnosis and evaluation of pre-eclampsia as a supplement to the already existing methods.
İnternal Karotid Arter Malpozisyonu Çok Kesitli Bilgisayarlı Tomografi ile Değerlendirilmesi: Faringeal Cerrahi Açısından Komplikasyon Analizi
(2018) Düzenli, Ufuk; Batur, Abdussamed; İlik, İbrahim; Ozgokce, Mesut; Yavuz, Alparslan; Gündüz, Ali Mahir; Akdenız, Hüseyın
Amaç: Basit faringeal cerrahi prosedürler sırasındainternal karotis arter zedelenmeleri kanama riskiaçısından felaketle sonuçlanabilir. Bu çalışmada internalkarotis arter servikal segmenti mediale dispozisyonu vebu varyasyonun \"rutin\" farengeal cerrahi işlemleraçısından olası risk faktörlerini değerlendirmektir.Yöntem: Bu çalışmada çok kesitli bilgisayarlı tomografi(ÇKBT) ile faringeal duvara indentasyon yapmış internalkarotid arter segmenti saptanan 28 hastanın 3 boyutluboyun tomografileri inceledi. Bu hastaların tamamı 15 yaşve üzeri idi. Hastaların son 12 ayda çekilen ÇKBTtetkiklerinde insidental tespit edilen medialeize-aberanservikal internal carotid arter (ICA) segmentleri esasalınarak çalışma planlandı. Anomalinin seyri ve karotisfaringealduvar mesafesi bilgisayarlı tomografide (BT) 3boyutlu olarak değerlendirildi.Bulgular: 28 hastanın 20’si kadın, 8’i erkek oluphastaların yaş aralığı 15 ile 83 arasındaydı. ÇKBTdeğerlendirmesinde medialize internal karotid arter 23vakada bilateral iken 5 vakamızda tek taraflıydı (2 vakasol, 3 vaka sağ aberran ICA). Weibel ve Fieldssınıflamasına göre; 10 hasta düşük (grade 1), 12 hasta orta(grade 2) ,16 hasta yüksek (grade 3) ,13 hasta aşırı yüksek(grade 4) olarak sınıflandırıldı. Duvara minimum uzaklık0,1 mm ve azami uzaklık 15 mm arasında değişmekteolup ortalama uzaklık 5,1 mm idi.Sonuç: Rutin faringeal cerrahi ve girişimsel işlemlergenellikle preoperatif radyolojik görüntülemeyapılmaksızın gerçekleşmektedir; ancak damaryaralanması açısından internal karotid arter seyrinin işlemöncesi ayrıntılı değerlendirilmesi büyük önem taşımaktaolup üç boyutlu ÇKBT tetkikinin bu anomalilerideğerlendirebilecek en etkin radyolojik görüntülemeyöntemi olduğu sonucuna varılmıştır.
Relationship of Pcna, C-Erbb2 and Cd44s Expression With Tumor Grade and Stage in Urothelial Carcinomas of the Bladder
(E-century Publishing Corp, 2014) Yildirim, Ayhan; Kosem, Mustafa; Sayar, Ilyas; Gelincik, Ibrahim; Yavuz, Alparslan; Bozkurt, Aliseydi; Bayram, Irfan
In the present study, the intention was to reveal the relationship of histological grade and stage with c-erbB2, CD44s, and PCNA immunoreactivity in bladder urothelial carcinomas (UC). In our study, we evaluated 46 items of transurethral resection material of patients submitted by YYU Faculty of Medicine, Main Department of Pathology, with a mass revealed in their bladder after clinical and radiological studies at our laboratories and who were diagnosed with urothelial carcinomas. PCNA, c-erbB2, and CD44s were applied in an immunohistochemical manner comprised from nine low-malignant potential papillary urothelial neoplasia, 23 low-grade papillary urothelial carcinoma, and 14 high-grade papillary urothelial carcinoma. Immunostaining was scored according to the percentage of positive cells. The immunohistochemical study demonstrated that the c-erbB2 and PCNA staining ratio increased when an increase occurred in stage and grade. The CD44s staining ratio decreased. C-erbB2, PCNA, and CD44s appear to be a useful marker in the assessment of the prognosis and treatment options in urothelial carcinomas.
Sex Estimation From the Clavicle Using 3d Reconstruction, Discriminant Analyses, and Neural Networks in an Eastern Turkish Population
(Elsevier Ireland Ltd, 2022) Demir, Ugur; Etli, Yasin; Hekimoglu, Yavuz; Kartal, Erhan; Keskin, Siddik; Yavuz, Alparslan; Asirdizer, Mahmut
Sex estimation of skeletal remains is an important aspect of forensic anthropology. The clavicle is a bone with relatively high accuracy in sex determination. In this study, 7 clavicular parameters were obtained using the CT images and 3D reconstruction of 360 cases equally distributed as 180 males and 180 females. Sex determination was made using univariate, linear, and stepwise discriminant analyses, and multilayer perceptron neural networks. Maximum sex determination accuracy of 85.3% was achieved with univariate analysis, 89.4% with linear discriminant analysis, 90.0% with stepwise discriminant analysis, and 91.4% with multilayer perceptron neural networks. Significant changes were observed in the MLC, APMD-R and CDC parameters according to age, and these were determined to affect the accuracy of sex determination in different age groups. In forensic anthropological studies, more reliable results can be obtained by considering the confounding factors during sampling. Although high accuracy rates can be achieved with neural networks, the results should be approached with caution.