Browsing by Author "Yazmalar, L."

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Fibromyalgia Frequency in Patients With Acne Vulgaris
(Bmj Publishing Group, 2015) Yazmalar, L.; Celepkolu, T.; Batmaz, I.; Sariyildiz, M. A.; Sula, B.; An, I.; Cevik, R.
The Relationship Between Shoulder Impingement Syndrome and Sleep Quality
(verduci Publisher, 2013) Tekeoglu, I.; Ediz, L.; Hiz, O.; Toprak, M.; Yazmalar, L.; Karaaslan, G.
BACKGROUND AND OBJECTIVES: The aim of this study was to examine potential relationship between subjective sleep quality and degree of pain in patients with shoulder impingement syndrome (SIS). MATERIALS AND METHODS: Fourty patients with shoulder impingement syndrome were evaluated using the Pittsburgh Sleep Quality Index (PSQI) and the Shoulder Disability Questionnaire (SDQ). Forty three of age and sex matched healthy subjects were included in the control group. RESULTS: There was a significant difference between the patient and control groups in terms of all PSQI global scores and subdivisions (p < 0.01). The pain scores assessed by SDQ were positively correlated with the scores for subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, and sleep disturbance (r = 0.49/p < 0.01, r = 0.44/p < 0.01, r = 0.36/p < 0.05, r = 0.40/p < 0.05, and r = 0.37/p < 0.05 respectively). The comparison of total SDQ pain and global PSQI scores also revealed a significant correlation (r = 0.54/p < 0.01). CONCLUSIONS: Subjective sleep disturbance connected to shoulder pain was found obviously in patients with SIS. For this reason, patients with shoulder pain due to SIS may benefit from the pain killers and cognitive-behavioral interventions that specifically target sleep disturbances. Further studies which contain polysomnographic assessments, as well as determine psychologic status are still needed to put forth sleep quality in patients with SIS.
Restless Legs Syndrome in Behcet's Disease
(Field House Publishing Llp, 2011) Ediz, L.; Hiz, O.; Toprak, M.; Ceylan, M. F.; Yazmalar, L.; Gulcu, E.
The prevalence of restless legs syndrome (RLS) and its association with the clinical features of Behcet's disease (BD) has not previously been elucidated. The inflammatory character, central nervous system involvement and neuropathies of BD led to this investigation of RLS risk in BD patients. A total of 116 BD patients and 104 healthy control subjects were included; seven BD patients were excluded because of concurrent diseases, pregnancy or alcohol misuse that might cause RLS symptoms, and the remaining 109 BD patients were included in the analysis. The prevalence of RLS was significantly higher in patients with BD (32/109; 29.4%) than in controls (5/104; 4.8%). No significant differences were found between BD patients with and without RLS with regard to the clinical features of BD. RLS severity positively correlated with age in BD patients. In conclusion, BD-related RLS should be considered in symptomatic RLS secondary to rheumatological disorders and BD patients should be examined for RLS. Further studies are needed to clarify the pathogenetic mechanisms underlying BD-related RLS.
Seasonal Disease Activity and Serum Vitamin D Levels in Rheumatoid Arthritis, Ankylosing Spondylitis and Osteoarthritis
(Makerere Univ, Fac Med, 2013) Yazmalar, L.; Ediz, L.; Alpayci, M.; Hiz, O.; Toprak, M.; Tekeoglu, I
Background: Vitamin D is a steroid hormone that plays essential roles in calcium and phosphorus metabolism, bone formation and mineralization homeostasis, also has a role in the maintenance of immune-homeostasis. Objective: We aimed to investigate seasonal serum vitamin D levels and seasonal disease activity in patients with Rheumatoid Arthritis, Ankylosing Spondylitis, and Osteoarthritis. Methods: Seventy-one Rheumatoid Arthritis patients, 72 Ankylosing Spondylitis patients, 74 knee Osteoarthritis patients and 70 healthy controls were recruited for the study. Bi-seasonal measurements of serum 25(OH)D vitamin were checked in either in July or August or September for summertime and either in December or January or February for wintertime. Disease activity were evaluated by Disease Activity Score-28, Bath Ankylosing Spondylitis Disease Activity Index, and Western Ontario and McMaster Universities Osteoarthritis Index in groups of Rheumatoid Arthritis, Ankylosing Spondylitis, and Osteoarthritis respectively. Results: We did not find any correlation between serum 25(OH)D levels and Disease Activity Score-28, Bath Ankylosing Spondylitis Disease Activity Index, and Western Ontario and McMaster Universities Osteoarthritis Index scores in winter and summer. The difference of Disease Activity Score-28 and Western Ontario and McMaster Universities Osteoarthritis Index scores between winter and summer seasons were not significant in Rheumatoid Arthritis and Osteoarthritis patients (p>0.05). The mean Bath Ankylosing Spondylitis Disease Activity Index score was significantly higher in winter than in summer (p<0.05). Consequently we did not find any correlation between variations of seasonal serum 25(OH)D and the disease activity in the patients with Rheumatoid Arthritis, Ankylosing Spondylitis, and Osteoarthritis. Conclusion: These results suggest that vitamin D does not have an important role in the seasonal disease activity of these diseases and that seasonal changes in disease activity may play an important role in evaluating Ankylosing Spondylitis patients rather than Rheumatoid Arthritis and Osteoarthritis patients and should be taken into account when examining these patients. These conclusions need to be validated in multicenter studies with high number of patients.
Serum Gdf-15 Level in Behcet's Disease: Relationship Between the Disease Activity and Clinical Parameters
(Bmj Publishing Group, 2015) Sariyildiz, M. A.; Yazmalar, L.; Batmaz, I.; Alpayci, M.; Burkan, Y. K.; Sula, B.; Bozkurt, M.
Sleep Quality, Depression and Anxiety in Carpal Tunnel Syndrome
(2008) Tekeoǧlu, I.; Gülcü, E.; Sayin, R.; Beşiroǧlu, L.; Yazmalar, L.
Objective: The purpose of this study was to examine the sleep disorders, anxiety and depression caused by CTS in patients, and whether electrodiagnostic study findings were associated with the severity of symptoms of sleep quality, anxiety and depression in patients. Materials and Methods: Using a case-control methodology, 87 electrophysiologically confirmed CTS patients with a mean age of 45±13 (27-62) years (86.9% women, n=73) and 50 controls with a mean age of 40±9.2 (21-56) years (54% women, n=27) were examined. Clinical neurological examinations of CTS patients and validated Turkish version of self-reported Sleep Quality Index, Beck Depression Scale and Beck Anxiety Scale were employed. Results: The majority of patients in the CTS group had worse symptoms of depression and anxiety, compared with the control group (p<0.05). The severity of CTS was not significantly associated with right and left hand utilization and the severity of symptoms of self-reported sleep quality, anxiety and depression scales. There were no statistically significant relationships between the electrodiagnostic findings and the patient functional status and symptom severity. Conclusion: Electrodiagnostic findings and patient CTS-related symptoms and sleep, anxiety and depression appear to be independent measures. Clinicians and researchers interested in CTS outcomes need to assess both. While depression and anxiety levels are found to be high in CTS, sleep-quality is relatively low. However, knowing that there is no correlation between the intensity of the illness and the number of symptoms with those variables, leads us to consider that the severity of the illness is evaluated on the self reports of patients. For this reason, physical impacts of the illness should also be evaluated as subjective.