Browsing by Author "Yel, Servet"

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Cardiovascular Evaluation and Serum Paraoxonase-1 Levels in Adolescents With Polycystic Ovary Syndrome
(Taylor & Francis inc, 2020) Cetin, Mecnun; Tuncdemir, Perihan; Karaman, Kamuran; Yel, Servet; Karaman, Erbil; Ozgokce, Mesut; Komuroglu, Ahmet Ufuk
The aim of our study was to evaluate whether cardiovascular disease risks seen in adults with polycystic ovary syndrome (PCOS) develop in adolescents with PCOS using conventional Doppler echocardiography (CDE) and tissue Doppler echocardiography (TDE) or not. The other aim was to investigate the association of paraoxonase-1 (PON-1) level with cardiovascular parameters. 30 PCOS patients and 30 control patients were included in the study. All patients were evaluated with TDE and CDE. Paraoxonase-1 levels of both groups were studied. In CDE study, myocardial performance index (MPI) was higher in the PCOS group than in the control group (0.54 +/- 0.11, 0.50 +/- 0.12, p = .049, respectively). In the TDE study, early diastolic myocardial velocity (E)'/late diastolic myocardial velocity (A ') was lower in PCOS group than in the control group (2.07 +/- 0.08, 2.44 +/- 0.10, p = .008, respectively). PON-1 was higher in PCOS group than in the control group (26.81 +/- 3.05, 18.68 +/- 1.18, p = .011, respectively). Cardiovascular disease risks, which are among the long-term complications of PCOS, seem to begin from the early stage of PCOS. The high PON-1 level was thought to increase in response to increased oxidative stress in PCOS.Impact statement What is already known on this subject? Polycystic ovary syndrome (PCOS) is one of the most commonly seen endocrinopathy in the adolescent age group. PCOS has detrimental effects on the cardiovascular system in the adult population which is reported in many studies. What the results of this study add? The result of this study showed that cardiovascular effects, which are among the long-term complications of PCOS, seem to begin from the early stage of PCOS. And also, serum paraoxonase-1 level increases in response to the oxidative stress in the adolescent with PCOS.
Examination of Sleep Disturbance and Sleep-Related Problems in Children With Type 1 Diabetes
(Galenos Publ House, 2024) Kupcu, Zekiye; Ozdemir, Funda Kardas; Baykal, Dilek ciftci; Guney, Guelcimen; Kara, Canan; Yel, Servet
BACKGROUND/AIMS: This research aimed to investigate the sleep disorders and sleep problems of children with type 1 diabetes (T1D). MATERIALS AND METHODS: This research was descriptive and cross-sectional. This research was conducted with 105 parents of children with T1D who were admitted to a training and research hospital between June and August 2022. In the collection of the research data, the "Introductory Information Form" and the "Sleep Disorder Scale for Children (SDSC)" were used. RESULTS: As a result of our research, the average total score of SDSC was found to be 47.60 +/- 12.740. According to this result, the level of sleep disorders of the children participating in this study was below the average score. Significant differences were found in the sub-dimensions of CONCLUSION: The parents participating in this study evaluated their children's sleep disorder levels as being below the average score. Since the sleep disorders of children with T1D are affected by familial characteristics and factors related to the disease, it is recommended to conduct further studies in order to identify sleep disorders and influencing factors so as to improve these conditions, and also to provide educational and counselling services to parents on these issues.