Browsing by Author "Yildirim, Ersin"

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The Association of a Precise-Dapt Score With No-Reflow in Patients With St-Segment Elevation Myocardial Infarction
(Sage Publications inc, 2022) Selcuk, Murat; Cinar, Tufan; Saylik, Faysal; Demiroz, Onder; Yildirim, Ersin
This study aimed to evaluate the association of admission PREdicting bleeding Complications In patients undergoing Stent implantation and subsEquent Dual Anti Platelet Therapy (PRECISE-DAPT) score with the development of no-reflow (NR) in patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). In this observational, retrospective study, 335 consecutive STEMI patients who were treated with primary PCI were included. We classified the study population into 2 groups: patients with a PRECISE-DAPT score <25 and those with a PRECISE-DAPT score >= 25. Overall, 30 (8.9%) patients developed NR. The mean PRECISE-DAPT score (20.03 +/- 15.32 vs 11.33 +/- 12.18; P = .005) was significantly higher in cases who developed NR. Moreover, arrhythmic complications, in-hospital shock, and in-hospital mortality rates were significantly higher in patients with a PRECISE-DAPT score >= 25 compared to those with a PRECISE-DAPT score <25. According to a multivariable analysis, the PRECISE-DAPT score was found to be independently linked with NR (odds ratio: 2.87, with P = .015). To our knowledge, these data are the first in major medical science databases to determine the relationship between the PRECISE-DAPT score and the NR phenomenon in patients with STEMI undergoing primary PCI.
Comparison of Monocyte With High Density Lipoprotein Cholesterol Ratio in Dipper and Nondipper Hypertensive Patients
(Future Medicine Ltd, 2019) Selcuk, Murat; Yildirim, Ersin; Saylik, Faysal
Aim: We aimed to compare the monocyte to HDL-cholesterol ratio (MHR) of nondipper hypertension (NDHT) and dipper hypertension patients. Patients & methods: A total of 162 patients were included in the study. Patients were grouped as dipper and nondipper according to 24-h ambulatory blood pressure recordings. Results: The MHR was significantly higher in nondipper hypertension group compared with control (p < 0.001) and dipper hypertension groups (p = 0.03). MHR, hs-CRP and red-cell distribution width (RDW) were independent predictors of nondipper hypertension. Area under the curve was 0.62 (p = 0.034) for MHR and 0.61 (p = 0.012) for hs-CRP in the ROC analysis. Conclusion: MHR has elevated levels in NDHT patients. Increased levels of MHR may evaluate as increased risk of cardiovascular events in NDHT patients.
Effect of Heroin on Right Ventricular Cardiac Performance
(Clinics Cardive Publ Pty Ltd, 2020) Selcuk, Murat; Yildirim, Ersin; Saylik, Faysal; Deniz, Ozgur; Mutluer, Ferit Onur
Objective: The aim of this study was to investigate the effects of heroin addiction. which is an important social and health problem, on right cardiac function. Methods: A total of 85 individuals were included in the study The study group comprised 45 patients smoking heroin and the control group was 40 healthy individuals with no drug addiction. Patients injecting heroin were excluded. Echocardiographic evaluation of patients using heroin was performed and compared with those in the control group. Results: The right ventricle and pulmonary artery diameters in the heroin group were found to be higher compared to the control group. The myocardial performance index (WI) was higher and more abnormal in the heroin group (0.48 +/- 0.22 vs 0.39 +/- 0.11, p < 0.05) whereas isovolumic acceleration d VA) of the right ventricle was significantly lower in the heroin group (2.92 +/- 0.69 vs 3.4 +/- 0.68 m/s(2), p < 0.01). No significant difference was observed between the groups with regard to the right ventricular ejection fraction (RVEF) (59.6 +/- 2.5 vs 60.6 +/- p = 0.08), tricuspid annular plain systolic excursion (TAPSE) (24.1 +/- 4.2 vs 24.5 +/- 2.4 mm,p = 0.7), tissue Doppler imaging S wave (TDI-S) (13.7 +/- 2.1 vs 13.8 +/- 2.1 cm/s, p = 0.86) and right ventricular fractional area change (RVFAC) (42.7 +/- 8.3 vs 43.9 +/- 3.5%, p = 0.4). Multivariate and univariate regression analyses revealed independent correlation between the pulmonary artery diameter and RVIVA, and heroin addiction. Conclusion: Heroin addiction negatively affected right ventricular function and more attention should be paid to the cardiac function of these patients.