Browsing by Author "Yildirim, F."

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Antidiabetic and Antioxidant Effects of Vitis Vinifera L. Cv. 'kara Erik' Seed Extract in Streptozotocin Diabetic Rats
(Scibulcom Ltd., 2017) Yildirim, B.A.; Kordali, S.; Yildirim, S.; Yildirim, F.; Ercisli, S.
In this study was aimed to investigate effects on the levels of liver and renal tissue CAT, MDA, SOD, GPx and GSH activities of Vitis vinifera L. cv. 'Kara Erik' seed extract on diabetic rats. A total of 28 male rats were randomly divided to four groups containing of 7 rats per group. Control Group: Received only vehicle 0.5% Carboxymethyl cellulose (CMC), STZ-DM (Streptozotosin-Diabetus mellitus) Group: Streptozotocin 60 mg/kg/IP single dose, VVE (Vitis vinifera L. seed extract) Group: Vitis vinifera seed extract 100 mg/kg/20days/po, STZ-DM+VVE Group: STZ as 60 mg/kg/IP single dose + VVE100 mg/kg/20days/po. At the end of these processes, the animals were sacrificed, liver and renal tissue were excised by dissection and evaluated. Catalase (CAT), Malondialdehyde (MDA), Superoxide dismutase (SOD), Glutathione peroxidase (GPx) and Glutathione (GSH) were measured in the liver and renal homogenisates. VVE was shown that the activity of CAT, SOD and GSH activities increased and decreased levels of MDA in diabetic rats. As a result, the results showed that oral administration of VVE extract reduced the levels of lIPid peroxides and improved the antioxidant activity in liver and renal tissues in rats treated with V. vinifera seed extract as compared with the diabetic and control rats. These results suggested that the V. vinifera L. cv. seed extract enhanced the antioxidant defense under hyperglycaemic conditions hence protected the liver and renal cells.
A Destructive Urban Transformation Project Resulting With A Social Transformation Process in Ankara-Turkey
(Elsevier France-editions Scientifiques Medicales Elsevier, 2011) Ilhan, I.; Yildirim, F.; Dertli, N.; Turan, M.; Tarihci, S.
Investigation of the Lipid Peroxidation, Antioxidant Enzymes, Antioxidant Vitamins, Oxidation Products of Nitric Oxide and Some Biochemical Parameters in Chicken With Infectious Bursal Disease (Ibd)
(Eugen Ulmer Gmbh Co, 2016) Ertekin, A.; Yildirim, B. A.; Yildirim, S.; Yildirim, F.; Tutuncu, M.
In the current study, lipid peroxidation, antioxidant enzymes, antioxidant vitamins, oxidation products of nitric oxide and some biochemical parameter levels in chicken with infectious bursal disease were investigated. Thirty chicken were used in the study, 7 in a control group of healthy individuals and the other 23 chickens were infected naturally. The level of advanced oxidation protein products (AOPP) was not affected by the treatment. Vitamin C (P<0.01), nitrite (P<0.01), catalase (P<0.001) and superoxide dismutase (P<0.001) levels were significantly decreased. The levels of malondialdehyde and nitrate increased significantly (P<0.001), while the amounts of ALT (P<0.05) and Albumin (P<0.001) decreased. We also found that changes in glucose, AST, triglyceride and total protein levels were not affected. On the other hand, increases in the levels of LDL (P<0.01), cholesterol and HDL (P<0.05) were significant.