Browsing by Author "Yildiz, Rahmi"

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Bibliometric Analysis of Neurocysticercosis Case Reports and Evaluation of Presented Cases
(Academic Press Ltd- Elsevier Science Ltd, 2025) Gurbuz, Esra; Aydemir, Selahattin; Barlik, Fethi; Saygin, Murat; Yildiz, Rahmi; Alkan, Sevil; Ekici, Abdurrahman
Neurocysticercosis (NCC) has been classified as a neglected tropical disease by the World Health Organization (WHO), with the condition being regarded as the most significant parasitic disease affecting the nervous system. Hence, the aim of this study was to conduct a review of previously published case reports on this topic in order to ascertain whether there is an increasing trend of NCC worldwide and evaluate the cases that have been presented. After a comprehensive search of the Web of Science Core Collection using the keywords "neurocysticercosis" and "case reports", studies were selected by applying inclusion criteria. Important data attributes that were extracted in plain text format included the document titles, publication years, journal names, author(s) name(s), keywords, institutions, and countries. In addition, to evaluate the cases, the age and gender of the patients, complaints on admission, localization of the cyst, and treatment procedure used were recorded in an Excel file. The bibliometric analysis was conducted using Biblioshiny. Additionally, GraphPad and Excel were employed for the creation of graphical representations. The dataset analyzed included 297 documents, 162 from various sources, with an average age of 12.2 years and 6.3 citations per document. The number of case reports tended to increase over the years. India and the USA were the leading contributors to NCC case reports, with 78 (26.3 %) and 64 (21.5 %), respectively. This was followed by Brazil, France, and Spain with 31 (10.4 %), 14 (4.7 %) and 13 (4.4 %) case reports, respectively. Moreover 55.5 % of the patients in the cases presented in the articles were male and 12.9 % were in the 21-25 age group. In regard to the cysts, 81.2 % were located in the brain and 15.1 % were in the spine. The most common complaints were headache and seizures in brain localized NCC cases and back pain and numbness or weakness in extremities in spine localized NCC cases. Albendazole was used in 174 (54.5 %) cases, praziquantel in 22 (6.9 %) cases, and ivermectin in five (1.6 %) cases. In conclusion, NCC continues to be an increasingly serious public health problem in India as well as developed countries such as the USA and European countries. NCC can be seen in all age groups, males are more susceptible than females, cysts are more localized in the ventricular system, and albendazole and/or paraziquentel are used in treatment. In addition, more comprehensive studies on the use of ivermectin in the treatment of NCC should be conducted, as success was achieved in cases where ivermectin was used in treatment.
Global Trends in Studies on the Presence of Demodex Spp. in Patients Diagnosed With Blepharitis
(Iranian Scientific Society Medical Entomology, 2024) Yildiz, Rahmi; Afsar, Milad; Elasan, Sadi
Background: The main objective of this study is to review publications on the presence of Demodex spp. in patients diagnosed with blepharitis worldwide and to analyse the trends and groups in this field. Methods: This bibliometric study was conducted to detect the presence of Demodex spp. in patients diagnosed with blepharitis worldwide between 1984 and 2023. For this purpose, 288 studies were examined as a result of searches using the keywords "Blepharitis and Demodex" in Web of Science (WOS) databases. All text data was analysed using VOSviewer software to ensure accuracy and reliability. In this study, analysis using text mining and data visualization techniques (bubble maps and graphs) helped to make the results more understandable. Results: This study provided information on 288 articles from WOS databases. The average total number of citations is 1305 and the H-index is 41. The majority of articles (63%) were published in the field of ophthalmology. The countries that published the most articles on this topic were the USA (24%), China (13%), and Turkey (11%). Conclusion: This study is the first bibliometric study of patients diagnosed with blepharitis due to Demodex spp. The most used keyword in blepharitis is Demodex. The most studied field of research is ophthalmology and the most studied country is the United States of America. The results of this bibliometric analysis conducted by us reveal global trends in the presence of Demodex spp. in patients diagnosed with blepharitis and provide important information for future directions of research.
Investigation of Mitochondrial Cytb Gene Region of Both Echinococcus Granulosus Eggs From Dogs and Cystic Echinococcosis Isolates Obtained From Sheep and Cattle by Molecular Methods
(Iranian Scientific Society Medical Entomology, 2024) Yildiz, Rahmi; Aydemir, Selahattin; Halidi, Ahmet Galip; Unlu, Ahmet Hakan; Yilmaz, Hasan
Background:We aimed to determine the common Echinococcus granulosus genotypes in A & gbreve;r & imath;, T & uuml;rkiye and to obtain information on the transmission of this parasite. Methods:Cystic echinococcosissamples from 100 slaughtered cattle and 100 slaughtered sheep and faecal samples from 200 stray dogs were included in 2021. Collected cyst fluid samples and faces were examined microscopically. DNA was isolated from the germinal membrane of the cysts and from the parasite eggs in the stool samples. The mitochondrial cytbgene region of the parasite was amplified by PCR. Genotypes were determined using the Basic Local Alignment Search Tool (BLAST) after sequence analysis of PCR amplicons. Results:The highest percentage of cysts was found in the lungs of sheep and the liver of cattle. In addition, 75% of sheep cysts and 25.6% of cattle cysts were fertile. Taenia spp./Echinococcus spp. eggs werefound in 6% of the faeces of 200 dogs ex-amined microscopically. E. granulosuseggs were detected in 4 out of 50 stool sam-ples analysed by PCR. All samples analysed by sequence analysis were identified as E. granulosuss.s. G1 genotype. Sequence comparisonrevealed revealed one or more-pointmutations in different regions of the five samples. Conclusion:E. granulosuss.s. G1 genotype, known as sheep strain, is common in the A & gbreve;r & imath;, T & uuml;rkiye. The controlled slaughter of livestock, especially sheep, and the avoidance of feeding hydatid cyst organs to dogs, together with public education, were necessary to prevent the spread of the disease.