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Browsing by Author "Yilmaz, Ahmet Seyda"

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    Article
    Baseline Characteristics of a Patient Cohort and Predictors of In-Hospital Mortality in Coronary Care Units (morcor-Turk) Trial in Türkiye
    (Kare Publ, 2024) Yilmaz, Ahmet Seyda; Kahraman, Fatih; Ersoy, Ibrahim; Taylan, Gokay; Kaya, Emin Erdem; Aydin, Ertan; Akkaya, Fatih
    Objective: The MORtality in CORonary Care Units in T & uuml;rkiye (MORCOR-TURK) trial is a national registry evaluating predictors and rates of in -hospital mortality in coronary care unit (CCU) patients in T & uuml;rkiye. This report describes the baseline demographic characteristics of patients recruited for the MORCOR-TURK trial. Methods: The study is a multicenter, cross-sectional, prospective national registry that included 50 centers capable of 24 -hour CCU service, selected from all seven geographic regions of T & uuml;rkiye. All consecutive patients admitted to CCUs with cardiovascular emergencies between September 1-30, 2022, were prospectively enrolled. Baseline demographic characteristics, admission diagnoses, laboratory data, and cardiovascular risk factors were recorded. Results: A total of 3,157 patients with a mean age of 65 years (range: 56-73) and 2,087 (66.1%) males were included in the analysis. Patients with arterial hypertension [1,864 patients (59%)], diabetes mellitus (DM) [1,184 (37.5%)], hyperlipidemia [1,120 (35.5%)], and smoking [1,093 (34.6%)] were noted. Non -ST elevation myocardial infarction (NSTEMI) was the leading cause of admission [1,187 patients (37.6%)], followed by ST elevation myocardial infarction (STEMI) in 742 patients (23.5%). Other frequent diagnoses included decompensated heart failure (HF) [339 patients (10.7%)] and arrhythmia [272 patients (8.6%)], respectively. Atrial fibrillation (AF) was the most common pathological rhythm [442 patients (14%)], and chest pain was the most common primary complaint [2,173 patients (68.8%)]. Conclusion: The most common admission diagnosis was acute coronary syndrome (ACS), particularly NSTEMI. Hypertension and DM were found to be the two leading risk factors, and AF was the most commonly seen pathological rhythm in all hospitalized patients. These findings may be useful in understanding the characteristics of patients admitted to CCUs and thus in taking precautions to decrease CCU admissions.
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    Rationale, Design, and Methodology of the Morcor-Turk Trial: Predictors of In-Hospital Mortality in Coronary Care Patients in Turkey
    (Kare Publ, 2023) Kahraman, Fatih; Ersoy, Ibrahim; Yilmaz, Ahmet Seyda; Atici, Adem; Tekin, Alpin Mert; Acar, Burak; Aygul, Nazif
    Background: Coronary care units are sophisticated clinics established to reduce deaths due to acute cardiovascular events. Current data on coronary care unit mortality rates and predictors of mortality in Turkey are very limited. The MORtality predictors in CORonary care units in TURKey (MORCOR-TURK) trial was designed to provide information on the mortality rates and predictors in patients followed in coronary care units in Turkey. Methods: The MORCOR-TURK trial will be a national, observational, multicenter, and noninterventional study conducted in Turkey. The study population will include coronary care unit patients from 50 centers selected from all regions in Turkey. All consecutive patients admitted to coronary care units with cardiovascular diagnoses between 1 and 30 September 2022 will be prospectively enrolled. All data will be collected at one point in time, and the current clinical practice will be evaluated (ClinicalTrials.gov number NCT05296694). In the first step of the study, admission diagnoses, demographic characteristics, basic clinical and laboratory data, and in-hospital management will be assessed. At the end of the first step, the predictors and rates of in-hospital mortality will be documented. The second step will be in cohort design, and discharged patients will be followed up till 1 year. Predictors of short- and long-term mortality will be assessed. Moreover, a new coronary care unit mortality score will be generated with data acquired from this cohort. Results: The short-term outcomes of the study are planned to be shared by early 2023. Conclusion: The MORCOR-TURK trial will be the largest and most comprehensive study in Turkey evaluating the rates and predictors of in-hospital mortality of patients admitted to coronary care units.