Browsing by Author "Yilmaz, H."

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A Case of Aural Myiasis Caused by Wohlfahrtia Magnifica in a Child in Turkey
(Refik Saydam National Public Health Agency (RSNPHA), 2017) Beyhan, Y.E.; Yilmaz, H.; Taş-Cengiz, Z.; Ayral, A.
Myiasis is the infestation of tissues and organs of vertebrate animals and humans by the larval stages of dipterous flies. In present case, a four year old child living in Silopi was applied to our clinic with complaints of otalgia, pruritus and otorrhea in the right ear. In the physical examination, aural fetor, secretion and several foreign bodies were observed. Twenty living maggots were removed from the external auditory canal (EAC) using surgical forceps. The maggots were identified as third phase larvae of Wohlfahrtia magnifica. In conclusion, patient should be examined for aural myiasis in case of otalgia, otorrhea, itching, and hearing impairments, especially in children.
Case Report: Hookworm Infection in a Patient With Severe Anemia
(2009) Yilmaz, H.; Taş Cengiz, Z.; Ciçek, M.; Dülger, A.C.
In this study, a patient who was hospitalized with a severe anemia in the Internal Medicine Clinic of the Health Research and Application Hospital of Yüzüncü Yil University for one week is presented. The patient had fatigue, paleness and dizziness for one month and approximately 12 kg weight lost for four mounts previous to admission.. Severe iron deficiency anemia was diagnosed in the patient by laboratory analyses. Because there were no hematologic factors associated with severe anemia, the stool examination was also performed. In the Parasitology Laboratory, stool microscopy of the patient revealed numerous ova of hookworm. General condition of the patient well improved with anti-parasitic and anti-anemia treatment. It was concluded that patients with iron deficiency anemia diagnosed in health centers should be also examined for the intestinal parasitic diseases encountered rarely, and physicians should consider non-endemic parasitic diseases in their provinces.
Comparison of Colistin-Carbapenem, Colistin-Sulbactam, and Colistin Plus Other Antibacterial Agents for the Treatment of Extremely Drug-Resistant Acinetobacter Baumannii Bloodstream Infections
(Springer, 2014) Batirel, A.; Balkan, I. I.; Karabay, O.; Agalar, C.; Akalin, S.; Alici, O.; Yilmaz, H.
The purpose of this investigation was to compare the efficacy of colistin-based therapies in extremely drug-resistant Acinetobacter spp. bloodstream infections (XDR-ABSI). A retrospective study was conducted in 27 tertiary-care centers from January 2009 to August 2012. The primary end-point was 14-day survival, and the secondary end-points were clinical and microbiological outcomes. Thirty-six and 214 patients [102 (47.7 %): colistin-carbapenem (CC), 69 (32.2 %): colistin-sulbactam (CS), and 43 (20.1 %: tigecycline): colistin with other agent (CO)] received colistin monotherapy and colistin-based combinations, respectively. Rates of complete response/cure and 14-day survival were relatively higher, and microbiological eradication was significantly higher in the combination group. Also, the in-hospital mortality rate was significantly lower in the combination group. No significant difference was found in the clinical (p = 0.97) and microbiological (p = 0.92) outcomes and 14-day survival rates (p = 0.79) between the three combination groups. Neither the timing of initial effective treatment nor the presence of any concomitant infection was significant between the three groups (p > 0.05) and also for 14-day survival (p > 0.05). Higher Pitt bacteremia score (PBS), Acute Physiology and Chronic Health Evaluation II (APACHE II) score, Charlson comorbidity index (CCI), and prolonged hospital and intensive care unit (ICU) stay before XDR-ABSI were significant risk factors for 14-day mortality (p = 0.02, p = 0.0001, p = 0.0001, p = 0.02, and p = 0.01, respectively). In the multivariable analysis, PBS, age, and duration of ICU stay were independent risk factors for 14-day mortality (p < 0.0001, p < 0.0001, and p = 0.001, respectively). Colistin-based combination therapy resulted in significantly higher microbiological eradication rates, relatively higher cure and 14-day survival rates, and lower in-hospital mortality compared to colistin monotherapy. CC, CS, and CO combinations for XDR-ABSI did not reveal significant differences with respect to 14-day survival and clinical or microbiological outcome before and after propensity score matching (PSM). PBS, age, and length of ICU stay were independent risk factors for 14-day mortality.
Consequences of Nacl Salinity on Growth and Ion Accumulation in Selected Strawberry Cutivars
(int Soc Horticultural Science-ishs, 2008) Yildiz, K.; Uzal, Oe.; Yilmaz, H.
Salt-tolerance of some strawberry cultivars was examined using frigo plants grown in hydroponics. The cultivars 'Tioga' and 'Rapella' were more salt-tolerant than strawberry cultivars 'Camarosa', 'Sweet Charlie', 'Dermarvel', 'Tudla', 'Northester' and 'Douglas'. Vegetative growth in these cultivars was better compared to strawberry cultivars 'Elvira', 'Aiko', 'Camarosa', 'Sweet Charlie', 'Dermarvel', 'Tudla', 'Northester' and 'Douglas' under 100 mM NaCI treatment. Considering vegetative growth parameters, cvs 'Dermarvel', 'Douglas' and 'Camarosa'. Generally, Na accumulation caused by NaCl was higher in sensitive cultivars than in tolerant cultivars. The Ca/Na and K/Na ratios were larger in tolerant cultivars. Malondialdehyde contents of all cultivars increased due to NaCl. Nevertheless, no relationship between malondialdehyde content and salt tolerance of cultivars could be determined.
Determination of Fruit Chemical Properties of Morus Nigra L., Morus Alba L. and Morus Rubra L. by Hplc
(Elsevier, 2011) Gundogdu, M.; Muradoglu, F.; Sensoy, R. I. Gazioglu; Yilmaz, H.
This study was carried out to determine the organic acid content, phenolic compound content, sugar content. vitamin C (ascorbic acid) content and total antioxidant capacity of white mulberry (Morus alba L), black mulberry (Morus nigra L.) and red mulberry (Morus rubra L) fruits grown in Van province of Turkey. It was determined that the chief organic acid in these mulberry species was malic acid ranging from 1.32 to 4.47g 100 g(-1) fw, followed by citric acid ranging from 0.39 to 1.08g 100g(-1) fw. Looking at the contents of phenolic compound, chlorogenic acid and rutin had come to the fore ranging from 0.12 to 3.11 mg g(-1) fw and from 0.85 to 1.42 mg g(-1) fw, respectively. Fruit glucose contents of the studied species were higher than their fructose contents, varying between 6.07 and 7.75g 100 g(-1) fw. Total antioxidant capacity and vitamin C contents of the mulberry species ranged from 4.49 to 13.99 mu mol TEg(-1) fw and from 11.30 to 24.42 mg 100 g(-1) fw, respectively. (C) 2011 Elsevier B.V. All rights reserved.
Determination of the Occurrence Frequency of Cryptosporidium Sp. in Children Brought To the Hospital With the Complaint of Diarrhea Using Different Methods
(Aloki Applied Ecological Research and Forensic inst Ltd, 2021) Ekici, A.; Unlu, A. H.; Halidi, A. G.; Aydemir, S.; Yilmaz, H.
Cryptosporidium is a parasite responsible for diarrhea in humans. Practitioners rarely routinely request Cryptosporidium diagnostic tests; thus, its prevalence is likely underrated. The prevalence of cryptosporidiosis among children brought to the hospital with the complaint of diarrhea was investigated using 3 different methods, comprising nested PCR, immunochromatographic testing, and microscopic examination with modified acid-fast staining. Cryptosporidium sp. was detected in 42/150 children with diarrhea (28%) and in 1/50 children in the control group (2%). The main complaint by children admitted to hospital with Cryptosporidium was diarrhea. Additionally, some clinical symptoms/signs like abdominal pain, nausea, vomiting, stool mucus, weakness, weight loss, and anorexia were correlated with cryptosporidiosis. Results from the 3 methods were compared and nested PCR and immunochromatographic testing were the most reliable. Among other pathogens and parasites found in stool samples, Cryptosporidium is a significant cause of hospitalization due to gastrointestinal disease in children in Van, Turkey.
The Effect of Humic Acid on Plant Growth, Phytoremediation and Oxidative Stress in Rapeseed (Brassica Napus L.) Grown Under Heavy Metal Stress
(Centenary University, 2022) Boysan Canal, S.; Bozkurt, M.A.; Yilmaz, H.
The aim of this study was to investigate the effects of humic acid (HA) applications on rapeseed (Brassica napus L.) growth, heavy metal uptake, bioconcentration factor (BCF), translocation factor (TF), tolerance index (TI), catalase (CAT), ascorbate peroxidase (APX) enzyme activities and hydrogen peroxide (H2O2) content in polluted soil with lead (Pb), chromium (Cr), cadmium (Cd), and zinc (Zn). Three doses of HA (Control, HA1:500 mg kg-1, HA2:1000 mg kg-1, HA3:2000 mg kg-1) were applied in pots. HA1, HA2, and HA3 applications increased plant growth parameters compared to polluted soil. Compared to the control, HA applications in polluted soil increased the Pb, Cr, Cd, and Zn concentrations in the plant. However, HA applications in polluted soil significantly decreased the heavy metal content in roots and shoots of the plant compared to polluted soil. BCF in both roots and shoots of the plants were greater than 1 for Pb, Cr, Cd, and Zn. However, specifically HA2 application decreased the shoot and root BCF values in polluted soil. TF was smaller than 1 in Pb, Cr, Cd, and Zn in polluted soil. On the other hand, HA applications for Cd increased TF values. Shoot TI decreased 17.37 %, and root TI decreased 9.09% in polluted soil. CAT and APX enzyme activities and H2O2 increased significantly in polluted soil. However, HA applications decreased CAT and APX enzyme activities and H2O2 content in rapeseed. It is concluded that HA application in Pb, Cr, Cd, and Zn polluted soil has a remedial effect on the development of rapeseed by reducing heavy metal content and oxidative stress. © 2022, Centenary University. All rights reserved.
The Effect of Jasmonic Acid on Germination of Dormant and Nondormant Pear (Pyrus Communis L.) Seeds
(Ista-int Seed Testing Assoc, 2008) Yildiz, K.; Muradoglu, F.; Yilmaz, H.
Jasmonic acid (JA) stimulated germination of dormant pear (Pyrus communis L.) seeds. Treatment of seeds with JA not only increased germination level, but also accelerated germination of dormant seeds according to control seeds. However, in the seeds stratified for 30 and more days, JA did not change total ratio of germination, but delayed the germination. The retarding effect of JA on germination was larger in seeds stratified for 90 days. Although JA stimulated germination to some degree but it was not as effective as stratification under cold condition in removal of dormancy in pear seeds.
The Effect of Triclabendazole (Fasinex) in Children With Fasciolosis
(1998) Yilmaz, H.; Oner, A.F.; Akdeniz, H.; Arslan, S.
Three children infected with Fasciola hepatica (FH) were treated with triclabendazole (TCZ; Fasinex). In the first two patients, firstly, albendazole (Andazole) was administered, but did not stop the excretion of FH eggs. To these two patients, TCZ was administered in a single oral dose of 10 mg/kg postprandially. Two month later, very few eggs were found in stool samples. So, the same dose of triclabendazole was secondly given to the patients. After this therapy. FH eggs have not been found in the repeated stool examinations for a follow up of one year. To the third patient, TCZ was administered in a single oral dose of 10 mg/kg together with food. This patient has remained free of complaints and stool samples were free from FH eggs for two months. In conclusion, TCZ may be used as a treatment of choice for human fasciolosis both in adults, and children.
Effect on Biochemical Parameters in Naturally Infected Calves With Giardiasis After Treatment With Albendazole in Van Province, Turkey
(2014) Ragbetli, C.; Tanritanir, P.; Yilmaz, H.; Yoruk, I.; Ozdemir, H.
The aim of this study was to investigate the changes in the blood serum levels of some biochemical parameters, lipid-soluble vitamins and trace elements in the calves naturally infected with Giardia spp. in Van region, before and after treatment with orally 20 mg/kg-1 albendazole three successive days. Serum samples were analyzed for biochemical parameters and some vitamins. In the infected animals, concentrations of creatinine, amylase levels were lower (p< 0.05). Glucose, urea, total protein, AST, ALT, sodium, potassium, retinol and α-tocopherol levels were seen significantly higher in the after treatment group (p< 0.05). There was no statistically significant difference in the concentration of total bilirubin, chloride and vitamin D3 between groups. All the animals were not encountered cysts or trophozoites of Giardia at the end of the treatment. The results of this study would suggest albendazole to be 100% effective against giardiasis in all of the calves in Van region.
Intestinal Parasites Detected in Süphan Primary Schoolchildren in Van
(2009) Taş Cengiz, Z.; Ciçek, M.; Akbayram, S.; Yilmaz, H.
This study was performed in order to determine the distribution of intestinal parasites among students of Süphan Primary School in Van in 2005. In the study, stool specimens were taken from 395 students (166 girls and 229 boys) between 7-15 years of age. The specimens were examined by native-Lugol, flotation and trichrome staining methods in the parasitology laboratory of Health Research and Training Hospital, Yüzüncü Yil University. One or more parasite species were detected in 28.9 % of the children. Parasitosis was detected in 28.3% of the girls and in 29.3% of the boys. Giardia intestinalis, Ascaris lumbricoides, Hymenolepis nana, Blastocystis hominis, Entamoeba histolytica/Entamoeba dispar, Entamoeba coli, Trichuris trichiura, Enterobius vermicularis, Iodamoeba butschlii, Endolimax nana were detected at the rates of 15.4%, 6.6%, 6.3%, 3.3%, 1.5%, 1.3%, 0.5%, 0.3%, 0.3% and 0.3%, respectively. In conclusion, it was observed that the socioeconomic status has an important impact on the frequency of intestinal parasites among primary school students, and the parasitosis is still a problem in the province.
Intestinal Parasitoses Detected in Primary Schoolchildren in the Van Province
(2009) Taş Cengiz, Z.; Akbayram, S.; Ciçek, M.; Yilmaz, H.
This study was carried out on school children in primary schools in the Van province in order to investigate the distribution of intestinal parasitoses. The study was conducted in 7-15 year-old primary schoolchildren during the years from 2003-2005. Stool specimens were taken from 2975 school children; of these, 1289 were female and 1686, male. The specimens were examined by native-Lugol, flotation and trichrome staining methods in the parasitology laboratory of the Health Research and Training Hospital, Yüzüncü Yil University. One or more parasite species were detected in 1916 (64.4%) stool specimens of 2975 children. Parasitosis was detected in 65.7% of females and in 63.4% of males. Blastocystis hominis, Giardia intestinalis, Entamoeba coli, Iodamoeba butschlii, Chilomastix mesnili, Endolimax nana, Entamoeba histolytica/Entamoeba dispar, Entamoeba hartmanni, Enteromonas hominis, Retortamonas intestinalis, Dientamoeba fragilis, Trichomonas hominis, Ascaris lumbricoides, Hymenolepis nana, Trichuris trichiura, Enterobius vermicularis and Fasciola hepatica were detected in 27.4%, 16.4%, 14.9%, 3.9%, 2.9%, 1.8%, 1.1%, 0.6%, 0.5%, 0.5%, 0.4%, 0.2%, 7.5%, 5.3%, 0.7%, 0.6% and 0.03% of the specimens, respectively. In conclusion, there are still high rates of intestinal parasitoses in school children in this region because care is not taken in hygiene and the socioeconomic status is low in the Van province.
A Nasopharyngeal Human Infestation Caused by Linguatula Serrata Nymphs in Van Province: a Case Report
(2011) Yilmaz, H.; Cengiz, Z.T.; Ciçek, M.; Dülger, A.C.
The reason for the presentation of this case is that Linguatula serrata, a parasite rarely encountered in humans, was found in a patient in Van province. The patient, who was 26 years old, lived in Erciş a town in Van province, East Turkey. She was admitted to the Outpatient Clinic of Infectious Diseases of Erciş Government Hospital with a complaint of coughing a few worms about 4 cm long from the oral cavity, and also sore throat, partial voice loss and vomiting. The polyclinic doctor suspected that the worm was a parasite but he could not make a diagnosis, and the patient was referred to Health Research and Training Hospital, Yüzüncü Yil University. The parasite was examined in the Parasitology Laboratory and it was observed that this parasite was the nymph of L. serrata whose mouth was surrounded with four hooks and had approximately 90 body segments with small hooks. No medical treatment was given to the patient except that gargling with saline solution was recommended. As a result, we think that physicians should consider L. serrata infestation in patients applying to health foundations with complaints such as pharyngitis accompanied by pharyngeal pain, coughing, sneezing and vomiting.
Organic Acid, Phenolic Profile and Antioxidant Capacities of Pomegranate (Punica Granatum L.) Cultivars and Selected Genotypes
(Elsevier Science Bv, 2012) Gundogdu, M.; Yilmaz, H.
In this study, organic acid and phenolic compound contents and antioxidant capacities of some standard Turkish pomegranates and formerly selected 5 promising local pomegranate genotypes in Pervari region of Siirt Province (Gundogdu, 2006) were determined. With respect to antioxidant capacities, the highest value (14.67 mmol TE L-1) was determined in Silifke awl pomegranate fruits among all examined cultivars and genotypes. Considering the organic acid contents of pomegranate juices, citric acid was identified to be the predominant organic acid and the highest value (2.1823 g L-1) was identified in 56PER19 genotype. No acetic acid content was identified in the examined cultivars and genotypes. In terms of phenolic compound contents, the highest value of gallic acid (6.361 g L-1) was identified in Cevlik pomegranate cultivar. The findings of study indicated that pomegranate cultivars and genotypes have important phytonutrients. Rather than the content of energy; the rich content of minerals, vitamins, organic acids and phenolic compounds make pomegranate an important source material for fruit processing industry. (C) 2012 Elsevier B.V. All rights reserved.