Browsing by Author "Yilmaz, Tevfik"

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Co-Occurrence of Lumbar Spondylolysis and Lumbar Disc Herniation With Lumbosacral Nerve Root Anomaly
(Medknow Publications & Media Pvt Ltd, 2014) Yilmaz, Tevfik; Turan, Yahya; Gulsen, Ismail; Dalbayrak, Sedat
Lumbosacral nerve root anomalies are the leading cause of lumbar surgery failures. Although co-occurrence of lumbar spondylolysis and disc herniation is common, it is very rare to observe that a nerve root anomaly accompanies these lesions. A 49-year-old male patient presented with sudden-onset right leg pain. Examinations revealed L5/S1 lumbar spondylolysis and disc herniation. At preoperative period, he was also diagnosed with lumbosacral root anomaly. Following discectomy and root decompression, stabilization was performed. The complaints of the patient diagnosed with lumbosacral root anomaly at intraoperative period were improved at postoperative period. It should be remembered that in patients with lumbar disc herniation and spondylolysis, lumbar root anomalies may coexist when clinical and neurological picture is severe. Preoperative and perioperative assessments should be made meticulously to prevent neurological injury.
The Effects of Caffeic Acid Phenethyl Ester on Inflammatory Cytokines After Acute Spinal Cord Injury
(Turkish Assoc Trauma Emergency Surgery, 2015) Ak, Hakan; Gulsen, Ismail; Karaaslan, Tamer; Alaca, Ilker; Candan, Aydin; Kocak, Havva; Yilmaz, Tevfik
BACKGROUND: The purpose of this study was to investigate the effects of Caffeic Acid Phenethyl Ester (CAPE) on proinflammatory cytokines, IL-1 beta and TNF-alpha, and explore its healing effect after acute spinal cord injury. METHODS: Forty-eight male Wistar-Albino rats were used in this study which was planned as three groups. All groups were divided into two sub-groups. Group la was the control group, in which only lower segment thoracic laminectomy was performed. In group lb, spinal cord trauma was performed with aneurysm clip. In the second group, serum physiologic was given systemically thirty minutes after trauma, and rats were sacrificed after the first and sixth hour. In the third group, CAPE was given systemically thirty minutes after trauma, and rats were sacrificed after the first and sixth hour. Serum IL-1 beta and TNF-alpha levels were analyzed by ELISA in the serum. Histopathological analysis was performed in damaged cord tissues. RESULTS: CAPE suppressed TNF-alpha and IL-1 beta levels in the serum. In histopathological evaluation, it was detected that CAPE decreased hemorrhage and necrosis. CONCLUSION: CAPE suppresses the levels of proinflammatory cytokines, TNF-alpha and IL-1 beta, after acute spinal cord injury in the early phase and contributes to the healing process.
Recurrent Gliosarcoma in Pregnancy
(Hindawi Ltd, 2014) Gulsen, Ismail; Ak, Hakan; Yilmaz, Tevfik; Bulut, Mehmet Deniz; Alkis, Ismet; Bayram, Irfan
Gliosarcoma is a rare tumor of the central nervous system and it constitutes about 1 to 8% of all malignant gliomas. In this report we are presenting a recurrent gliosarcoma case during a pregnancy in a 30-year-old woman. This is the first report presenting gliosarcoma in the pregnancy.