Browsing by Author "Yuca, S.A."
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Article Anal Protrusion of Ventriculo-Peritoneal Shunt Catheter: Report of Two Infants(2004) Yilmaz, N.; Kiymaz, N.; Yilmaz, C.; Çaksen, H.; Yuca, S.A.In general, treatment of hydrocephalus requires the application of a ventriculo-peritoneal shunt. Despite the peritoneal cavity being convenient for absorption of cerebrospinal fluid, multiple complications related to the shunt tends to develop within this area. The most frequent complications are abdominal. A rare complication can occurs with perforation of the organs located in peritoneal cavity by the catheter when infection occurs. Here we report two cases (because of unusual presentation) of shunt complication, they were operated for hydrocephalus. Acute traumatic anal protrusion of the peritoneal catheter occurred in the first case while a spontaneous anal protrusion during follow-up period, in the second case. The predisposing factors were thought to be previous abdominal infection and the use of trocar during operation in the first case and chronic irritative effect of the ventriculo-peritoneal catheter in the second case. © 2004, IOS Press. All rights reserved.Article A Case of Bartter’s Syndrome Associated With Nephrocalcinosis Presenting With Tetany(2004) Ataş, B.; Çaksen, H.; Tuncer, O.; Kirimi, E.; Arslan, S.; Erol, M.; Yuca, S.A.A 10-year-old boy was admitted to hospital with a 3 month history of intermittent spasms of the wrists and ankles, and twitching of the eyelids. He also had polyuria, polydipsia, nocturnal enuresis, fatigue and constipation since he was a toddler. Physical examination revealed normal blood pressure, myokymia on the right eyelid and bilateral carpopedal spasms. Laboratory investigation revealed hypocalcemia, hypokalemia, increased plasma renin and aldosterone, hypercalciuria, metabolic alkalosis, and bilateral medullary nephrocalcinosis. Cranial computed tomography was normal. Based on the clinical and laboratory findings he was diagnosed as having Bartter’s syndrome, which is characterized by hypochloremia, hypokalaemia and metabolic alkalosis associated with potassium renal leakage, with normal blood pressure despite increased plasma renin activity. It is well known that tetany is not uncommon in the neonatal form of Bartter’s syndrome and nephrocalcinosis is usually not present in the classic form. Interestingly, our patient had both the clinical manifestations of the neonatal form and of the classic form of Bartter’s syndrome. In conclusion, we would like to emphasize that both the clinical manifestations of neonatal and classic forms of Bartter’s syndrome (as an overlapping syndrome) might be seen in children and that Bartter’s syndrome should also be considered in children with tetany as in our case. © 2004, IOS Press. All rights reserved.Article A Case of Idiopathic Intracranial Hypertension Related With Vesicoureteral Reflux(2011) Akgün, C.; Taşkin, G.A.; Akbayram, S.; Kaya, A.; Temel, H.; Yuca, S.A.; Çaksen, H.Pseudotumor cerebri is idiopathic intracranial hypertension. The etiology of this syndrome has not been fully clarified. Excess cerebrospinal fluid production, scarcity of cerebrospinal fluid absorption, intracranial venous pressure elevation, increased intracranial blood volume are all thought to be responsible. The symptoms of the disease may be ordered according to prevalence as follows: headache due to increased intracranial pressure, blurred vision and diplopia. A thirteen-year-old female patient was brought in with complaints of headache, double and blurred vision. Systemic arterial hypertension (140/70 mmHg) was determined. Vesicoureteral reflux was detected as the hypertension etiology. In this article a rare pseudotumor cerebri case is presented secondary to vesicoureteral reflux which caused hypertension.Article A Case of Langerhans Cell Histiocytosis With Anal Fistula(Kurume University School of Medicine, 2010) Akbayram, S.; Akgun, C.; Ozen, S.; Kaya, A.; Tuncer, O.; Yuca, S.A.; Oner, A.F.Langerhans cell histiocytosis (LCH) is an uncommon clinically heterogeneous disorder characterized by the proliferation and accumulation of Langerhans cells with local infiltration of tissues and organ destruction. LCH takes many clinical forms, affecting different systems and different sites in the same system with variable outcomes. Bone, skin, lymph node, pituitary, liver, lung, bone marrow and spleen involvement can be seen in patients with LCH. Involvement of the perianal site is rare. In this article, a 16-month-old boy with multiple organ involvement including skin, liver, lung, and bone is presented. Aside from these systemic involvements, he also had a simple anal fistula. According to our best knowledge, this case of LCH with anal fistula is only the second to be reported in childhood. We would like to emphasize that LCH may be associated with anal fistula; therefore, we suggest that patients with LCH should be examined for this condition.Article Celiac Disease With Celiac Crisis(TIP ARASTIRMALARI DERNEGI, 2010) Dogan, M.; Yuca, S.A.; Acikgöz, M.; Doǧan, S.Z.; Kaya, A.; Cesur, Y.Celiac crisis is a life threatening and very rare complication of Celiac disease. Clinically, it is characterized by severe diarrhea, dehydration and metabolic disturbances like hypokalemia, hypomagnesemia, hypocalcemia, hypoproteinemia. A 2.5-years-old-girl with diarrhea, weight loss, abdominal distention, extremities edema, vomit which occurred after the beginning of supplementary nutrition was presented to emphasize that celiac crisis should be keep in mind in patient with gastrointestinal symptoms, which are best known in celiac disease, metabolic disturbance and abdominal distention.Article Comparison of Various Treatments in Childhood Brucellosis(2006) Yuca, S.A.; Ceylan, A.; Çaksen, H.; Kirimi, E.; Yilmaz, C.; Bay, A.The aim of this study was to evaluate the effectiveness of different drug combinations for treatment of brucellosis in children. Sixty children (mean age 9.2 ± 3.1 years, range 10 months to 15 years) were treated with four different drug combinations. The diagnosis of brucellosis was established by positive serum agglutination titer, and/or the isolation of Brucella species from blood cultures. The most frequent findings were fever and arthritis in 12 (20%) and 13 (21.6%) patients respectively. The children under 8 years old comprised Group 1 and 2, and older than 8 years comprised Group 3 and 4 according to treatment regimens. Nine patients (Group 1) were treated with trimethoprim-sulfamethoxazole (TMP-SMZ) for 45 days plus ceftriaxone for 5 days and, rest nine patients (Group 2) were managed with TMP-SMZ for 45 days plus gentamicin for 5 days. Twenty-one patients (Group 3) were managed with doxycycline for 45 days and ceftriaxone for 5 days and, other 21 (Group 4) patients were managed with doxycycline for 45 days and gentamicin for 5 days. All patients recovered. Relapse and improvement rates were similar for all groups (P >0.05). Each regimen was effective in the treatment of childhood brucellosis. Using cheaper drugs such as doxycycline and gentamicin in children 8 years of age and older, and TMP-SMZ and gentamicin in children 7 years of age or younger for the treatment of brucellosis in children is a practical and useful approach in our region and in the developing countries. © 2006 - IOS Press and the authors.Article Congenital Primary Hypothyroidism Associated With the Rare Form of Nonimmune Hydrops Fetalis(2010) Yuca, S.A.; Cesur, Y.; Kirimi, E.; Sari, S.; Kaya, A.; Doǧan, M.We present a male newborn born with diffuse edema and ascites. A diagnosis of congenital primary hypothyroidism was made based on thyroid hormone levels of total T4 1.74 μg/dL, free T4 0.30 ng/dL and TSH >75 μIU/mL and thyroid hormone replacement therapy was initiated. At day 15 of therapy, the thyroid function tests of the patient reached normal limits, and his edema and ascites regressed. In this report we present a newborn case of hypothyroidism that was accompanied by nonhydrops fetalis. We want to emphasize that congenital hypothyroidism may present with severe symptoms such as hydrops.Article The Effect of 25-Hydroxyvitamin D3 on the Immune System(Freund Publishing House Ltd, 2009) Dogan, M.; Erol, M.; Cesur, Y.; Yuca, S.A.; Zehra Doǧan, S.Aim: To examine the effect of 25-OH vitamin D3 on the immune system in patients with nutritional rickets. Methods: Fifty-three patients were included in our study between April 2002 and March 2004. Diagnosis of rickets was based on clinical, biochemical and radiological examinations. Cell surface markers (CD), complement factors (C), and immunoglobulin (Ig) levels were determined to find out any relationship between rickets and immune system deficiency. Results: Among the causes of admission to hospital, fever (66%) and coughing (62.2%) were the most frequent. Pneumonia was accompanied by rickets in 47.1% of the cases. Plasma CD4 levels before the treatment were higher than those in the post-treatment period, whereas CD20 and CD56 levels were lower. Conclusion: B cell and natural killer cell reduction which occur because of vitamin D deficiency may contribute to the development of pneumonia and other infections in patients with nutritional rickets. © Freund Publishing House Ltd.Article Ellis-Van Creveld Syndrome(TIP ARASTIRMALARI DERNEGI, 2008) Cesur, Y.; Yuca, S.A.; Üner, A.; Yuca, K.; Arslan, D.Ellis-van Creveld syndrome (EVCS) or chondroectodermal dysplasia is a rare autosomal recessive disorder characterized by a variable spectrum of clinical findings. Classical EVC syndrome comprises a tetrad of clinical manifestations of chondrodystrophy, polydactyly, ectodermal dysplasia, and cardiac defects. The patient presented with short stature, polydactyly, triangular face and dental dismorphism was found appropriately as radiographic with ectodermal dysplasia. In addition to the presence of single atrium, mitral, tricuspid and pulmonary valve insufficiency and pulmonary hypertension wererevealed by echocardiography. Her history involved a sister who was dead in 3-month-ages.Article A Forgotten Difficult Entity:ozena Report of Two Cases(2010) Yuca, S.A.; Yuca, K.; Kiroǧlu, A.F.; Yakut, F.Atrophic rhinitis or ozena is a chronic nasal disease characterized by progressive atrophy of the nasal mucosa and underlying bone, accompanied by the formation of foul smelling, thick, dry crusts in the greatly enlarged nasal cavities. Although the incidence of ozena is greatly diminished, it is still encountered rarely. The etiology of ozena still remains enigmatic but hereditary, infectious, developmental, endocrine and nutritional factors have been implicated. We describe two patients with endoscopical, clinical evidence and computed tomography findings of atrophic rhinitis along with a review of the current literature.Article Infantile Digital Fibromatosis (Inclusion Body Fibromatosis) Observed in a Baby Without Finger Involvement(2013) Kaya, A.; Yuca, S.A.; Karaman, K.; Erten, R.; Dogan, M.; Bektas, M.S.; Ustyol, L.A 9-day-old male baby was hospitalized after his birth due to some swells under the skin. The hard consistency nodules observed under the skin all over the body of the patient were of different size, and presented lesions, among which the biggest was 1 × 1 cm. No lesions were observed on the fingers. By superficial ultrasonography, multiple isoechoic hypoechoic lesions were observed among the muscle plan. In thoracolumbar magnetic resonance imaging, multiple massif lesions retaining peripheral contrast (the biggest was 1.7 × 1.4 cm large) had been observed under the skin muscle plans, between the muscles of the extremities. The biopsy was positive for smooth muscle actin, but negative for desmin, S100, and CD34. These findings were diagnosed as infantile digital fibromatosis (IDF) (inclusion body fibromatosis). The case was presented with an objective to illustrate and remind that IDF can be observed in babies without finger involvement.Article Juvenile Nasopharyngeal Angiofibroma(2010) Garça, M.F.; Yuca, S.A.; Yuca, K.Review of the literature was performed to define the optimal treatment of patients with juvenile nasopharyngeal angiofibroma (JNA). The prognosis for this disease is extremely good if diagnosed well in time and if the tumor has not extended intracranially. Preoperative selective arterial embolization has decreased intraoperative blood loss and facilitated resection of larger tumors. Transnasal endoscopic resection preserves both the anatomy and physiology of the nose, requires less rehabilitation days after surgery, and is highly successful for selected patients. Radiation therapy is generally reserved for larger and/or unressectable tumors but has severe complications. Radiosurgery has several advantages over surgery or classic radiation therapy. However, further experiences and studies are required to confirm the usefulness of radiosurgery on JNA.Article Prevalence of Overweight and Obesity in Children and Adolescents in Eastern Turkey(2010) Yuca, S.A.; Yilmaz, C.; Cesur, Y.; Doǧan, M.; Kaya, A.; Başaranoǧlu, M.Objective: The aim of this study was to estimate the prevalence of overweight and obesity in school children in Eastern Turkey. Methods: This study included 9048 school children aged 6-18 years. The subjects were classified as overweight and obese, according to the International Obesity Task Force. Results: We found prevalence of overweight of 11.1% in the studied population. It was detected that 2.2% of the population in the study was obese; 2.1% of males and 2.3% of females. While the prevalence of obesity was extremely low before 9 ages and after 15, it reached to high values at puberty and just before pubertal period in boys. The prevalence of overweight was higher in girls and reached to peak point at pubertal ages. Generally, the prevalence of obesity and overweight was slightly higher in girls than in boys, although the boys were more obese in prepubertal ages. Conclusion: Overweight and obesity are concerns for children and adolescents in low socio-economic status regions as well. © Journal of Clinical Research in Pediatric Endocrinology.Article Vitamin D Deficiency Rickets in Infants Presenting With Hypocalcaemic Convulsions(University of the West Indies, 2013) Cesur, Y.; Yuca, S.A.; Kaya, A.; Yilmaz, C.; Bay, A.Aim: Hypocalcaemia evaluation of the clinical, biochemical and radiological features of 91 infants with rickets who presented as hypocalcaemic convulsions. Subjects andMethods: Ninety-one hypocalcaemic infants who were brought to hospital with convulsion and diag-nosed with rickets related to vitamin D deficiency according to their clinical, biochemical and radio-logical features were retrospectively reviewed. Results: Mean values of the laboratory data were as follows: calcium 5.55 ± 0.79 mg/dL, phosphorus 4.77 ± 1.66 mg/dL, alkaline phosphatase 1525.5 ± 925.4 U/L and parathormone 256.8 ± 158.3 pg/mL. Serum 25-OH vitamin D levels were below normal (< 20 ng/mL) in 37 infants. Conclusion: Vitamin D deficiency should be considered in infants presenting with hypocalcaemia. To avoid complications such as convulsions, clinicians should give vitamin D supplementation to such infants.