Browsing by Author "Yuksel, H"

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Abdominal Malignant Mesothelioma in a Mouse
(Australian veterinary Assn, 2002) Yener, Z; Karaca, T; Yuksel, H
Angiokeratomatous Papilloma Associated With Papillomavirus in a Calf
(Amer Coll vet Pathologist, 2003) Gulbahar, MY; Yuksel, H; Aslan, L
A female 8-month-old Simmental calf was presented with a history of a gradually enlarging mass in the ventral abdominal skin since 4 months of age. The mass was well circumscribed, lightly pigmented, and rough surfaced with many fine fissures and was attached to the skin by a relatively broad pedicle. On cut section, there was a border between the reddish-black stroma and overlying epithelium, including hemorrhagic foci of variable sizes. Histologically, the tumor was papillomatous with angiokeratomatous features and irregular hyperplasia with epidermal rete ridges and dilated vascular channels filled with blood in the superficial dermis. In the epidermis, orthokeratotic hyperkeratosis, variably sized keratohyalin granules, and many koilocytes, some of which had papillomavirus (PV) genus-specific structural antigen-positive nuclei, were also observed. Cells lining the dilated vascular spaces were positive for vimentin and alpha-smooth muscle actin but negative for factor VIII-related antigen, desmin, and PV. The lesion was regarded as an angiokeratomatous papilloma and was similar to other angiomatous lesions.
Assessment of Proliferative Activity by Agnor and Pcna in Prostatic Tissues of Ram Lambs Implanted With Zeranol
(Blackwell Publishing, 2005) Gulbahar, MY; Yuksel, H; Guvenc, T; Okut, H
The aim of this study was to assess cellular proliferation using silver-stained nucleolar organizer regions (AgNOR) and the proliferating cell nuclear antigen (PCNA) in various tissues in the prostate of ram lambs implanted with increasing zeranol doses and to compare the sensitivity of different tissues of lamb prostate to zeranol. Twenty-four Akkaraman lambs were implanted with increasing zeranol doses, including 12 mg (n = 8), 24 mg (n = 8) and 96 mg (n = 8), with eight lambs serving as controls. After 33 days, the prostate tissues of the lambs were stained using AgNOR and PCNA techniques. The prostate tissues were divided into two compartments - the epithelial tissues, including glandular acinus, collecting duct and penile urethra, and the non-epithelia] tissues.. including interstitial tissue and striated muscle. AgNOR dots and PCNA index on each prostatic tissue were counted under a light microscope and were evaluated statistically. AgNOR staining in the treatment groups showed a higher score in the non-epithelial tissues than the epithelial components, whereas the PCNA index was significant in the epithelia] tissues and non-epithelial, tissues had very low. PCNA immunostaining. According to the PCNA index, collecting duct epithelium showed more sensitivity to increasing zeranol doses and according to AgNOR counts, there was no difference of sensitivity to zeranol among tissues of the same origin. Both AgNOR counts and PCNA indexes seem to be valuable proliferating markers for the epithelial components of ram prostate, but PCNA index had no significance in relation to the non-epithelial components in contrast to AgNOR counts. Therefore, the controversial results arising from the combined use of both techniques as proliferating markers for the ram prostate should be considered in further studies.
Congenital Synchronous Adenomas of Meibomian and Moll Glands of the Eyelid in a Calf
(Czech Academy Agricultural Sciences, 2005) Yuksel, H; Gulbahar, MY; Aslan, L
This report describes meibomian adenoma (MA) and moll gland adenoma in a female, 1.5-months-old, crossbreed calf. Macroscopically, the mass was 3 x 1.5 x 0.5 cm in size and 5.35 g in weight; its shape was gray-reddish and it was localized on the right lower eyelid. Microscopically, the mass was composed of lobules of various sizes separated with a septum, which included well-differentiated sebaceous cells and apocrine secretory epithelium, with no an association of both gland types.
Pathological Changes in the Carp Exposed To Iron Sulphate
(indian veterinary Journal, 2006) Yuksel, H; Ural, M; Dorucu, M; Karadas, E