Browsing by Author "Yurttas, V"

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Effects of Topical Chlorhexidine Applied To the Rabbit Nasal Mucosa
(Elsevier Sci Ltd, 2003) Çankaya, H; Özen, S; Kiroglu, F; Yurttas, V
Objective: To search the effects of administration of various concentrations of a wide-spectrum antimicrobial agent, chlorhexidine, to the nasal mucosa. Material and methods: About 0.20, 0.12, 0.06 and 0.03%, concentrations of chlorhexidine gluconate were applied to the rabbit nasal mucosa as one puff twice a day throughout 5 days. Another group, treated with serum saline to the nose, behaved as the control group. On the fifth day following drug administration, specimens were taken from nasal mucosa of the rabbits and examined under light microscope. Results: As a result of comparison between drug treated group and control group, with increasing drug concentrations progressively increased neutrophil infiltration in mucosa, ciliary loss in cells, and occasional metaplasia were observed. Conclusion: There is a linear, positive and strong association between concentrations of chlorhexidine and its irritative effects on rabbit nasal mucosa. While 0.20 and 0.12% concentrations of chlorhexidine cause excess irritation on the nasal cavity, 0.06 and 0.03% concentrations of chlorhexidine gluconate causes lower irritation and effects on the animals which have experimentally induced rhinosinusitis must be evaluated. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
Monostotic Fibrous Dysplasia Originating From Ethmoid Bone
(Annals Publ Co, 2004) Kutluhan, A; Kiroglu, AF; Yurttas, V; Arslan, H; Özen, S
We present a case of monostotic fibrous dysplasia of the ethmoidal sinus in an 11-year-old boy. This condition is of interest to the otorhinolaryngologist because of the difficulty of differential diagnosis and treatment. This tumorlike growth was not restricted to the right ethmoidal sinus, but also compressed the orbit and the globe. Endoscopic and transnasal removal of the mass with a drill was performed under general anesthesia. No residual tumor was observed 6 months later.
Possible Role of Helicobacter Pylori in the Etiopathogenesis of Chronic Otitis Media
(Lippincott Williams & Wilkins, 2005) Kutluhan, A; Yurttas, V; Akarca, US; Aydin, A; Tuncer, I; Ugras, S
Objective: To investigate a possible contribution from Helicobacter pylori to the etiopathogenesis of chronic otitis media. Study Design: Prospective clinical trial. Methods: Tympanomastoidectomy, radical mastoidectomy, and modified radical mastoidectomy procedures were performed according to the pathology of ear disease. Biopsy specimens were taken from middle ear, mastoid antrum, and tympanic orifice of eustachian tube. Helicobacter pylori DNA was extracted from these biopsy specimens by using nested polymerase chain reaction. Results: Helicobacter pylori DNA was detected in 3 (7.9%) of 38 chronic otitis media patients. Conclusion: Even though it is possible to detect Helicobacter pylori in middle ear cleft in chronic otitis media, its role in the etiopathogenesis of the issue is controversial.
When Can Lateral Sinus Thrombosis Be Treated Conservatively
(B C decker inc, 2004) Kutluhan, A; Kiris, M; Yurttas, V; Kiroglu, AF; Ünal, Ö
Objective: The purpose of this study was to review the clinical manifestations, radiologic findings, and treatment modalities of our cases with lateral sinus thrombosis (LST). Method: Documents of patients with LST, diagnosed and treated from 1995 to 2001. in our clinic, were examined retrospectively. Results: Four patients with the diagnosis of LST were treated during this period. Among the clinical manifestations of these patients, the most frequently encountered symptoms were earache and headache, in addition to otorrhea and hearing loss. Four cases had chronic otitis media, three with cholesteatoma and one with polyps. Delta sign was detected in three cases on computed tomography, whereas a suspicious image was noted in one case. This case underwent magnetic resonance angiography, and the diagnosis of LST was established conclusively. In two cases, because pus was aspirated via lateral sinus punctures performed intraoperatively, these sinuses were explored and obliterated following radical mastoidectomy. Because pus was not aspirated via punctures of the other two cases, their sinuses were not explored. Only radical mastoidectomy was performed surgically for these cases. Dual antibiotics and low-dose anticoagulant therapy were given concomitantly to all cases in the postoperative period. Recanalizations of the nonobliterated lateral sinuses were detected with Doppler ultrasonography of internal jugular vena at 15 days and 3 months after the termination of postoperative treatment. Conclusion: Clinical findings and radiologic techniques play an important role in the diagnosis of LST. In the treatment, if pus is found in the lateral sinuses, it is necessary to explore, clean, and obliterate them, whereas in cases in which the aspirates do not contain pus, mastoidectomy is sufficient. On the other hand, a low dose of anticoagulant can be used together with antibiotics in the nonobliterated lateral sinuses.