Browsing by Author "Zeteroglu, Sahin"
Now showing 1 - 6 of 6
- Results Per Page
- Sort Options
Article A Case of Transverse Vaginal Septum Diagnosed During Labor(Aves, 2005) Ustun, Yusuf; Ustun, Yaprak Engin; Zeteroglu, Sahin; Sahin, Guler; Kamaci, MansurTransverse vaginal septum is the result offliulty canalization of the embryonic vagina. We described a case of transverse vaginal septum with a small central aperture diagnosed during labor. An 18-years-old girl at 28 weeks of gestation presented to our obstetric department complaining of symptoms of preterm delivery. Pelvic and vaginal ultrasonography, with gynecologic examination established a diagnosis of transverse vaginal septum in mid vagina. An incision in the vaginal septum allowed us to see the head of the fetus in the vagina. The diagnosis of transverse vaginal septum was confirmed during labor and excision of the septum prevented the uterine rupture.Article Induction of Labor With Misoprostol in Pregnancies With Advanced Maternal Age(Elsevier Science Bv, 2006) Zeteroglu, Sahin; Sahin, Guler H.; Sahin, Huseyin A.Objective: The objective was to compare the efficacy and complications of intravaginal misoprostol application with oxytocin infusion for induction of labor in advanced aged pregnancies with a Bishop score of <6. Study design: A hundred advanced aged (>= 35 years) pregnant patients with a Bishop score of <6 were randomized into two groups. The first group (50 patients) received 50 mu g intravaginal misoprostol four times with 4 h intervals and the second group received oxytocin infusion for induction of labor starting from 2 mIU/min and was increased every 30 min with 2 mIU/min increments up to a maximum of 40 mIU/min. The time from induction to delivery, the route of delivery, fetal outcome, and maternal complications were recorded. Statistical analyses were performed using the Mann-Whitney U, Chi-squared and t tests to determine differences between the two groups. A p value <= 0.05 was considered significant. Results: Misoprostol was superior for induction of labor in advanced aged pregnancies with Bishop score of <6, as the mean time from induction to delivery was 9.61 +/- 4.12 h and 11.46 +/- 4.86 h in the misoprostol and oxytocin groups respectively, with a significant difference between the groups (p = 0.04). The rate of vaginal delivery was higher in the misoprostol group (84.0%) than in the oxytocin group (80.0%), but the difference did not reach significance (p = 0.60). The rates of placental abruption and postpartum hemorrhage were similar in both groups and no cases of uterine rupture occurred. The 1- and 5-min mean Apgar scores were 6.98 +/- 1.17 to 9.08 +/- 0.99 and 6.88 +/- 1.81 to 9.00 +/- 1.35 in the misoprostol and oxytocin groups respectively, with no significant differences between the groups (p = 0.74, p = 0.83). No cases of asphyxia were present. The rate of admission to the neonatal intensive care unit was similar in both groups. Conclusion: Intravaginal misoprostol seems to be an alternative method to oxytocin in the induction of labor in advanced aged pregnant women with low Bishop scores, as it is efficacious, cheap, and easy to use. But large studies are necessary to clarify safety with regard to the rare complications such as uterine rupture. (C) 2005 Elsevier Ireland Ltd. All rights reserved.Article A Prospective Randomized Study Comparing Misoprostol and Oxytocin for Premature Rupture of Membranes at Term(Taylor & Francis Ltd, 2006) Zeteroglu, Sahin; Engin-Ustun, Yaprak; Ustun, Yusuf; Guvercinci, Mehmet; Sahin, Guler; Kamaci, MansurObjective. The aim of this randomized trial was to compare the efficacy and safety of vaginal misoprostol and oxytocin for cervical ripening and labor induction in patients with premature rupture of membrane ( PROM) at term. Methods. Ninety-seven women with PROM at term were assigned randomly to receive intravaginal misoprostol or oxytocin. The primary outcome measure was the induction - delivery interval. Secondary outcomes included the number of women who delivered vaginally within 12 hours of the start of the induction in the two groups, the cesarean, hyperstimulation, and failed induction rates, the mode of delivery, and the neonatal outcome. Results. Forty-eight women were assigned to intravaginal misoprostol and 49 to oxytocin administration. The mean interval from induction to delivery was 10.61 +/- 2.45 hours in the misoprostol group and 11.57 +/- 1.91 hours in the oxytocin group ( p = 0.063). The rates of vaginal delivery were 83.3% and 87.7% and cesarean delivery were 16.7% and 8.2% in the misoprostol and oxytocin groups, respectively. Neonatal outcomes were not significantly different. Of the cases, 8.3% in the misoprostol group and 8.2% in the oxytocin group revealed uterine contraction abnormalities. Conclusion. Our study demonstrates that, intravaginally, misoprostol results in a similar interval from induction of labor to delivery when compared to oxytocin.Article Protective Effect of Erythropoietin on Ischemia-Reperfusion Model in Rat Ovary(Ortadogu Ad Pres & Publ Co, 2010) Kolusari, Ali; Kamaci, Mansur; Zeteroglu, Sahin; Altunay, Hikmet; Sahin, H. GulerObjective: In this study, the purpose was to investigate the effects of erythropoietin (EPO) on ischemia-reperfusion model that was made by experimental ovarian torsion- detorsion. Material and Methods: Twenty five Wister albino type rats were used in the study. They were randomly divided into three groups. Ten rats consisted the group that received no erythropoietin after the detorsion performed on 24th hour after ovarian torsion (group 1); 10 rats consisted the group that received intraperitoneal EPO after the detorsion that was performed at the 24th hour of ovarian torsion (group 2) and five rats consisted the sham group (group 3). After the surgical operation, right ovaries of all groups were excised on 7th day and blood samples were taken. Histopathologic findings and blood parameters of three groups were compared. Statistical analyses were made by SPSS package. One way ANOVA and t-test for independent samples were used. Results: Histopathologic findings of the group that received EPO were statistically different from the group that did not received EPO. In the group that did not receive EPO, tissue integrity deteriorated with partial necrosis and in some, there was near to total necrosis. In the group that received EPO, no necrosis was seen. After the treatment in the EPO administered group, the blood hemoglobin, hematocrit and red blood cell count were high and the differences were statistically significant. Conclusion: In ischemia-reperfusion model that was performed by ovarian torsion-detorsion, the histopathologic findings of the group that received EPO were different from the other groups, and the difference was statistically significant. In the cases of surgical detorsion that was made after ovarian torsion, intraperitoneal EPO injection had positive effects on tissue life.Letter Re: Comment To "peripartum Hysterectomy in a Teaching Hospital in the Eastern Region of Turkey(Elsevier Ireland Ltd, 2006) Zeteroglu, Sahin; Sahin, Guler; Kamaci, MansurArticle Uterine Artery Catheterisation and Selective Leiomyoma Embolization: Patient Acceptance and Clinical Outcome(Galenos Yayincilik, 2007) Zeteroglu, Sahin; Caliskan, Eray; Harman, Mustafa; Sengul, Muzaffer; Coskun, Ebru; Tiras, Bulent; Kamaci, MansurObjective: To evaluate the patient acceptance and clinical outcome after selective uterine leiomyoma embolization. Materials and Methods: Twenty-four women with symptomatic uterine fibroid were recruited for this study. Selective uterine leiomyoma embolization proceeded until complete vascular occlusion was achieved. The main outcome measure was the decrease in the leiomyoma volume and factors that predict it. Pearson correlation analysis and linear regression analysis were performed to identify possible correlates and predictors of decrease in leiomyoma volume. Patient satisfaction was assessed by asking the subjects to indicate their degree of satisfaction on a five-point scale. Results: The mean age of the patients was 41.5 +/- 4.9 (Range: 28-52). The mean leiomyoma volume before the procedure was 157 +/- 214 cm(3) which was calculated to be 44 +/- 66 cm3 with a 76 +/- 17% (Range: 30-99%) decrease in the mean leiomyoma volume at the end of one year. Correlation analysis revealed that only preoperative estradiol level was positively correlated with the extent of decrease in the leiomyoma volume (r=0.54, p=0.005). This was also proved in the regression analysis (beta=0.25, p=0.01). During the follow-up 17 (70.8%) patients had complete remission of the symptoms, 5 (20.8%) had partial remission and 2 (8.3%) had no clinically significant change. Twenty patients (83.3%) were completely satisfied, 2 were satisfied and 2 were dissatisfied with the leiomyoma embolization procedure. Discussion: There is a positive correlation between the preoperative estradiol level and the extent of the decrease in the leiomyoma volume after the embolization procedure. As leiomyoma is a hormone dependent tumor, the shrinkage of the leiomyoma seems also dependent on the estradiol levels before the precedure besides the incurred ischemic necrosis secondary to arterial embolization.