Browsing by Author "Özen, S."
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Article A Case of Parasitic Myoma Diagnosed by Immunohistochemistry(2004) Kamaci, M.; Özen, S.; Zeteroǧlu, Ş.; Oral, H.; Şengül, M.; Kolusari, A.A case of parasitic myoma diagnosed by immunohistochemistry is presented. The importance of histopathological and immumohistochemical procedures in the differential diagnosis of parasitic myoma from stromal tumors was discussed.Article Non-Reactive Tuberculosis Mimicking Histopathological Features of Kikuchi's Disease: a Case Report(2002) Kösem, M.; Karakök, M.; Özbay, B.; Özen, S.Article Pigmented Villonodular Synovitis Within Baker's Cyst: the Role of Mr-Arthrography(Elsevier BV, 2003) Harman, M.; Arslan, H.; Doǧan, A.; Özen, S.; Ipeksoy, Ü.We report a case of pigmented villonodular synovitis (PVNS) within Baker's cyst in a 55-year-old man who admitted to hospital with palpable popliteal mass. The mass was examined with ultrasonography (US), magnetic resonance imaging (MRI) and magnetic resonance arthrography (MRA). MRA was the best modality in the demonstration of the connection of the lesion with the joint space. In this study, we emphasized on the importance of the MRA in the PVNS within Baker's cyst. To the best our knowledge, this is the first report that illustrates the MRA characteristics of a PVNS within Baker's cyst. © 2002 Elsevier Science Ireland Ltd. All rights reserved.Article Primary Aneurysm of the Greater Saphenous Vein: Case Report and Literature Review(2010) Ekim, H.; Başel, H.; Odabaşi, D.; Özen, S.Primary venous aneurysm is a rare vascular abnormality that can occur throughout the venous system. We report a proximal greater saphenous vein aneurysm in a twenty one-year old male. A venous duplex ultrasonographic examination showed a fusiform venous aneurysm (5 cm in diameter) of the proximal greater saphenous vein containing occluding thrombus adherent to its wall and extending to saphenofemoral junction. Operation was performed due to apparent symptoms and the potential risk for thromboembolic complications. Aneurysm was exposed through a vertical left femoral incision. It was totally filled with thrombi. Histopathological examination of the aneurysmal wall demonstrated fibrocellular thickening with irregular vascular proliferation with multiple reduplications of internal elastic lamina. Because of the risk of thromboembolism, saphenous vein aneurysm containing occluding thrombus extending to saphenofemoral junction should be treated surgically.Article Primary Venous Aneurysm of the External Jugular Vein(2002) Ekim, H.; Özen, S.Article Serum Levels of Gastrin, and Insulin-Like Growth Factor (igf-1) in Patients With Gastro-Esophageal Cancer(2007) Dülger, H.; Izmirli, M.; Şekeroǧlu, M.R.; Alici, S.; Özen, S.; Özcan, S.Gastrin and insulin-like growth factor (IGF-1) seem to play a significant role in cell proliferation of mammalian. In this study, we were aimed at investigating the serum levels of gastrin and IGF-1 in patients with gastric cancer and esophagus cancer. In 68 patients with gastric (40 patients) and esophagus (28 patients) cancer and 30 healthy adults were measured serum levels of gastrin, IGF-1, CEA, CA 19-9, CA 125 and growth hormone. All these parameters have been increased in both cancer groups (gastric and esophagus) than those of control group and these increase were significantly for serum levels of gastrin, CEA, CA 125 and growth hormone (p<0.05). It is concluded that in patients with gastric and esophagus cancer a significant increase of serum gastrin can be found and increased gastrin levels play a role in gastric and esophageal carcinogenesis.Article Small Cell Carcinoma of the Esophagus: Report of a Case With Review of the Literature(2002) Alici, S.; Özen, S.; Kotan, Ç.Primary small-cell carcinoma of the esophagus is a rare tumor that disseminates early and has a uniformly poor prognosis if untreated. We report on a patient with esophageal small-cell carcinoma treated with combination chemotherapy following surgical resection. A 48-year-old female had an ulcerated tumor in the distal part of the esophagus, which was microscopically diagnosed as esophageal small-cell carcinoma. Computed tomography (CT) of the chest and abdomen showed no lymphadenopathy or distant metastatic disease. Chemotherapy plus radiation therapy was planned but the patient refused the proposed treatment due to socieconomic reasons. Subsequently, subtotal esophagectomy with lymphadenectomy (3 periesophageal nodes) was performed in another hospital. The histopathologic diagnosis of the primary tumor was small-cell carcinoma and the resected lymph nodes also contained metastatic deposits. On the second postoperative month she was admitted with hepatic metastases. Combination chemotherapy with etoposide 120 mg/m2/day on days 1 to 3, and cisplatin 75mg/m2/day on day 1, given intravenously (i.v.) every 3 weeks was started. After 3 courses, the patient achieved complete remission. Esophageal small-cell carcinoma is an aggressive tumor. Patients with disseminated disease should receive combination chemotherapy along with symptomatic treatment.