Serum Levels of Gastrin, and Insulin-Like Growth Factor (igf-1) in Patients With Gastro-Esophageal Cancer
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Date
2007
Journal Title
Journal ISSN
Volume Title
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Abstract
Gastrin and insulin-like growth factor (IGF-1) seem to play a significant role in cell proliferation of mammalian. In this study, we were aimed at investigating the serum levels of gastrin and IGF-1 in patients with gastric cancer and esophagus cancer. In 68 patients with gastric (40 patients) and esophagus (28 patients) cancer and 30 healthy adults were measured serum levels of gastrin, IGF-1, CEA, CA 19-9, CA 125 and growth hormone. All these parameters have been increased in both cancer groups (gastric and esophagus) than those of control group and these increase were significantly for serum levels of gastrin, CEA, CA 125 and growth hormone (p<0.05). It is concluded that in patients with gastric and esophagus cancer a significant increase of serum gastrin can be found and increased gastrin levels play a role in gastric and esophageal carcinogenesis.
Description
Keywords
Esophagus Cancer, Gastric Cancer, Gastrin, Igf-1
Turkish CoHE Thesis Center URL
WoS Q
Q4
Scopus Q
Q4
Source
UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi
Volume
17
Issue
3
Start Page
138
End Page
142