Browsing by Author "Şahin, H.A."

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Calcium Antagonists
(2000) Şahin, I.; Onbaşi, K.; Şahin, H.A.; Onbaşi, O.; Üstün, Y.
Calcium antagonists are a heterogeneous group of drugs which block the entry of calcium into the smooth muscle, resulting in vasodilation. They are used for the treatment of hypertension, angina pectoris, supraventricular tachycardia, atrial fibrillation and flutter, subarachnoid hemorrhage. Also they can be used for the treatment of biliary and intestinal colic, migraine, esophageal spasm, preterm labor, left ventricular diastolic dysfunction, Raynaud's phenomenon, and bipolar disorders. These drugs can be divided into three groups: The dihydropyridine group (nifedipine, nitrendipine, nisoldipine, nicardipine, isradipine, felodipine, amlodipine, lacidipine, nimodipine), phenylalkylamine group (verapamil) and the benzothiazepine group (diltiazem). They can also be used in the elderly patients and patients with COPD, diabetes, renal insuffiency, gout, hyperlipidemia with safety. The short acting group has been shown to increase the risc of myocardial infarction. For this reason, the long-acting drugs have been shown to be more safe. Calcium antagonists have a broad indication spectrum of usage for therapy of several diseases.
Helicobacter Pylori
(2001) Onbaşi, K.T.; Şahin, H.A.; Şahin, I.; Güler Şahin, H.; Onbaşi, O.
Helicobacter pylori is a Gram-negative organism and appears to be the most common worldwide human infection. Infection due to Helicobacter pylori can lead to the development of gastritis, peptic ulcer disease, gastric cancer and MALT lymphoma. Helicobacter pylori can be viewed as a true pathogen. Helicobacter pylori was identified in 1983, but we are still in dark about many aspects of the organism itself, its transmission, how it causes disease, and how we should clinically managing this infection. In spite of the large number of studies in this field there are still unexplained questions.
Prevention of Cancer Through Lifestyle Changes
(2006) Uǧurluer, G.; Şahin, H.A.
Cancer is one of the leading causes of death and an abundance of evidence suggests that lifestyle factors including smoking, typical high-fat, refined-sugar diet and physical inactivity play role in the development of majority of cancers. It has been estimated that 30-40 percent of all cancers can be prevented by lifestyle and dietary measures. In this paper the effects of diet and physical inactivity on frequently seen cancers and protective effects of foods are reviewed. Diet and physical inactivity take place among major factors for cancer promotion by inducing insulin resistance and hyperinsulinemia. Elevated levels of serum insulin impact on liver primarily, increasing the production of insulin-like growth factor I (IGF-I) while reducing the production of insulin-like growth factor binding protein 1 (IGFBP-1) and resulting in stimulation of tumor cell growth and inhibition of apoptosis (programmed cell death). Adopting a diet low in fat and high in fiber-rich starch foods, combined with regular aerobic exercise might control insulin resistance, reduce serum markers of cancer and consequently the risk for many different cancers.
Raynaud's Phenomenon in Healthy Population Who Admitted To the Hospital in Van Region, Turkey
(2003) Şahin, I.; Onbaşi, K.T.; Onbaşi, O.; Üstün, Y.; Mercan, R.; Şahin, H.A.; Görpelioǧlu, S.
Raynaud's phenomenon is a vasospastic disease and is characterized with ischemia of the digits, nose and ears. The vasospasm can be triggered by cold weather, cold water or emotional stress and is followed by triphasic color changes. First white color (ischemia), than blue color (congestion and cyanosis) and at last red color change (reactive hyperemia) can be observed. The prevalence is reported between 0,5 to 20 percent in different studies and is dependent on genetic, occupational, and environmental factors. The purpose of our study was to determine the prevalence of RP in a eastern part of Turkey among healthy subjects. A total of 251 people were included to the study. This cross-sectional study was conducted between April 2000 and July 2000 at the University Hospital and at the State Hospital in Van, Turkey. The participants were interviewed and examined to diagnose RP and a questionnaire and color charts were used. A total of 251 (134 women (53.4%), 117 men (46.6%)) subjects participated in this study. The overall mean age was 28.93±11.15. Definite RP was detected in 10 subjects according to at least two color changes (3.98%). They consisted of 6 women and 4 men. Mean age was 23.5±5.38. Four patients responded positively two color changes and six patients for three color changes. All patients who had symptoms had told their symptoms appeared in both hands. Probable RP was diagnosed in 20 patients with only one color change (7.96%). Mean age was 27.05±11.01 in probable RP group. Only 11 of 30 patients applied to any medical unit for RP (36.6%). The prevalence of RF was less found than literature perhaps it can be said that there is a strong influence of the climate in comparison to other contributing factors.
The Role of Family Physicians in the Primary Health Care of the Elderly
(2006) Tekin, N.; Şahin, H.A.
The current situation and problems of elderly care in Turkey are overviewed in this article. Ageing is an emerging phenomenon in the World and Turkey and contributing to a change in the country's age group composition. Elderly patients with chronic health problems are a common presentation in general practice. The family physicians, who take clinical education on geriatrics during their residency, can play an important role for the primary health care of the elderly and for the health care given in the geriatric care centers. Asa a result this will help the improvment of geriatrics and family medicine disciplines.
Telemedicine
(2003) Şahin, H.A.; Şahin, H.G.; Onbaşi, K.T.; Şahin, I.
Advances in telecommunication and computer industry are turning the concept of a global community into a reality. In the medical industry, telemedicine would be useful in improving health care quality, creating alternatives for transportation of patients and health care professionals. It would allow the exchange of data and radiographs before the transfer of patients between referring and receiving hospitals, increase self-diagnostics and home monitoring, allow real-time video teleconferencing between remotely located users over computer systems, provide rehabilitation and long-term support to the people with disabilities, thus saving lives and reducing medical costs due to early detection of serious pathology. Telemedicine offers new possibilities for multidisciplinary care of patients, allowing direct communications between different, complementary and geographically distant specialists. Thus, it is possible to form committees in small hospitals where all specialties are not represented. New and enhanced telecommunication links between community and academic hospitals show promise for reducing isolation and enhance lifelong learning opportunities for rural health care providers, reduce unnecessary referrals to specialists, and consequent savings to the patients, accompanied by more efficient usage of specialists' time.