Browsing by Author "Akpolat, N."

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Bazex Syndrome: Acrokeratosis Paraneoplastica in Association With Simultaneous Multiple Genitourinary Tumors
(Elsevier Inc., 2000) Atilla, M.K.; Yilmaz, Y.; Bekerecioglu, M.; Akpolat, N.; Kösem, M.; Aydin, S.
We report a patient with Bazex (Bazex-Dupre-Christol) syndrome in association with multifocal basal cell carcinoma, epidermoid carcinoma of the lung, adenocarcinoma of the prostate, and possibly undifferentiated carcinoma of the bladder. To our knowledge, this is the first report of a patient with Bazex syndrome that consisted of four tumors, including two genitourinary tumors. (C) 2000 Elsevier Science Inc.
Carcinoid Tumor of the Stomach a Rare Form of Gastrointestinal Carcinoid Tumor: a Report on Three Cases
(2001) Kotan, C.; Kösem, M.; Özgören, E.; Ilhan, M.; Sönmez, R.; Akpolat, N.
Between 1994 and 1999 three patients with gastric carcinoid tumors were diagnosed at Yüzüncü Yil University Medical Faculty, Department of Surgery. Their ages were 65, 80, and 50 years, and all were male. The major complaints were epigastric pain, dysphagia, loss of appetite and weight, postprandial vomiting and in one patient, hematemesis and melena. None of the patients had carcinoid syndrome. The tumor was located in the upper portion of the stomach in one case and distal portion of the stomach in two cases. All three patients were initially diagnosed as adenocarcinoma of the stomach due to the endoscopic appearance of the tumor and histologic evaluation of the endoscopic biopsy. Because of the diagnosis of gastric carcinoma, two of them underwent subtotal gastrectomy and the other had a total gastrectomy. Histological examination of the resected materials showed well differantiated carcinoid tumors. Two cases had lymph node metastasis. Tumor cells in the stomach were immunoreactive for chromogranin A and neuron specific enolase and Grimelius positive for argyrophil cell detection. This paper presents a literature review and describes these three cases.
The Effects of Hyaluronic Acid on Myringoplasty in Rats
(1999) Kutluhan, A.; Ugras, S.; Inalkac, E.; Akpolat, N.
Tympanic membrane perforations arise from a variety of causes. Some of them require myringoplasty. In this study, we used hyaluronic acid, a polysaccharide with high-molecular-weight which may be obtained commercially and affects modulations of cell function. An experimental myringoplasty was performed on rats in which a chronic dry tympanic membrane perforation was formed. While physiological saline was embedded in Gelfoam® which was supported under and over the graft, in group 1, hyaluronic acid embedded gelfoam was used in group 2. Better epithelization, less calcification and scar tissue were established in group 2 myringoplasties. This study shows that hyaluronic acid may be used in myringoplasty especially in myringosclerotic tympanic membrane perforations.
Elastosis Perforans Serpiginosa
(1997) Dilek, F.H.; Ugras, S.; Akpolat, N.
A 21-year-old male with brown keratotic papules on the nape of his neck was admitted to our clinic. Lesions were in characteristic arcuate and serpiginous patterns. The diagnosis of elastosis perforans serpiginosa (EPS) was confirmed by skin biopsy. The pathogenesis of EPS is still unclear. There is evidence for the transepidermal elimination of morphologically and biochemically abnormal elastic fibers. EPS was described in idiopathic, penicillamine induced and connective tissue disorder associated forms. In this article, we described and discussed the clinical and morphologic data in view of the literature.
Inflammatory Pseudotumor of the Lung Associated With Anemia: a Case Report and Review of the Literature
(2000) Yalcinkaya,; Demirtas, I.; Ayakta, H.; Akpolat, N.; Dilek, I.; Dilek, D.H.
Inflammatory pseudotumor of the lung is a benign tumor which is rarely seen. A mass in the left lung was observed in the chest roentgenogram of an 8 year-old boy while investigating for anemia. Preoperative investigations could not render the exact diagnosis. Pneumonectomy was required in exploratris thoracotomy. Histopathologic diagnosis was fibrohistiocytic type of inflammatory pseudotumor. Four months after the operation, anemia was cured without any further treatment.
The Place of Tonsillar Focal Infection in Tonsillectomy Bleeding in Chronic Tonsillitis
(2000) Kutluhan, A.; Kiroglu, F.; Akpolat, N.; Akdeniz, H.; Ugras, S.; Kiris, M.
Purpose: The aim of this study is to investigate whether there is any factor which influences tonsillectomy bleedings among clinical and histopathological findings. Methods: 380 patients who underwent tonsillectomy due to chronic tonsillitis were included in the study. The patients were divided into two groups according to peroperative bleedings. Group 1, included the patients whose bleedings stopped spontaneously or with gauze tampon and Group 2, the patients whose bleedings stopped with suturation-ligation or cauterisation. Results: Although there was no difference between the groups in age, sex, acute tonsillitis attack number, tonsil volume, lymphoide hyperplasia, lymphocyte infiltration to surface epithelium, epithelial defect, plasma cell and fibrosis; a statistical difference was present in view of polymorphonuclear leucocyte occurence against Group 1. Conclusion: We consider that an acute infection limited to the tonsils, exists in some cases with chronic tonsillitis and therefore this state may become a minor factor causing to bleeding in tonsillectomy.
The Relationship Between Ostial Patency and Medical Treatment in Acute Maxillary Sinusitis: an Experimental Study
(2002) Kutluhan, A.; Inalkaç, E.; Kiroglu, A.F.; Akpolat, N.; Kiriş, M.
OBJECTIVES: We investigated the relationship between ostial patency and medical treatment in an experimental model of acute maxillary sinusitis. DESIGN AND METHODS: Forty healthy New Zealand white rabbits were assigned to two groups. The left maxillary sinus ostia were filled with absorbable gelatin sponge in one group (n=20). In the other group, half of the ostuim was blocked by bone particles and tissue adhesive (Histoacryl). Following induction of acute maxillary sinusitis, each group was divided into four subgroups, one of which was left untreated. The other subgroups received systemic antibiotic therapy plus topical administration of physiological saline solution, a decongestant, and a steroid, respectively, for 10 days. All rabbits were monitored for four weeks. Each week nasal smear samples were obtained for neutrophil and leucocyte counts. In the end, maxillary sinus biopsies were obtained to determine the extent of healing. RESULTS: There were no significant differences between subgroups having the same ostium patency. However, compared to the subgroups with patent ostia, corresponding subgroups with semi-patent ostia exhibited significantly increased nasal smear and nasal biopsy scores starting from the second week. CONCLUSION: The degree of ostial patency seems to have a significant role in the treatment of acute maxillary sinusitis.