Elastosis Perforans Serpiginosa

Abstract

A 21-year-old male with brown keratotic papules on the nape of his neck was admitted to our clinic. Lesions were in characteristic arcuate and serpiginous patterns. The diagnosis of elastosis perforans serpiginosa (EPS) was confirmed by skin biopsy. The pathogenesis of EPS is still unclear. There is evidence for the transepidermal elimination of morphologically and biochemically abnormal elastic fibers. EPS was described in idiopathic, penicillamine induced and connective tissue disorder associated forms. In this article, we described and discussed the clinical and morphologic data in view of the literature.