Browsing by Author "Altiparmak, Ibrahim Halil"

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Association of Resting Heart Rate and Arterial Stiffness in Healthy Adults
(Pera Yayincilik Hizmetleri, 2016) Altiparmak, Ibrahim Halil; Erkus, Muslihittin Emre; Kocaarslan, Aydemir; Gunebakmaz, Ozgur; Kaya, Zekeriya; Sezen, Yusuf; Demirbag, Recep
Introduction: The arterial stiffness and resting heart rate (HR) are independent predictors of cardiovascular diseases. There are a few data about the association of HR with arterial stiffness in healthy men subjects. We aimed to evaluate this relationship in healthy male adults in the present study. Materials and Methods: A total of 50 volunteer healthy-nonsmoking male individuals (mean age: 40 +/- 12 years) enrolled in this observational study. According to the HR, the individuals were classified as group I, who have HR 50-70 beats/min (n=25) and group II, who have HR 71100 beats/min (n=25). History of the enrolled adults was recorded and they were physically examined. Blood pressure, body mass index and waist/hip ratio were measured in accordance with standard protocol. Arterial age and aortic pulse wave velocity (aPWV)indicating direct measurement of arterial stiffness were calculated by TensioMed (TM) Arteriograph. Results: There were no statistically significant differences between two groups with regard to age, body mass index, waist/hip ratio, systolic and diastolic blood pressure (for all p>0.05). The arterial age and aPWV were significantly higher in group II than group I (both; p<0.001). HR shows significant positive correlation with systolic blood pressure, body mass index, arterial age and aPWV (for all p<0.001). Conclusion: We conclude a relation between the HR and the increased arterial age and aortic pulse wave velocity levels in healthy male individuals. However, further studies are needed to clarify the pathophysiologic mechanisms responsible for the association between high HR and arterial stifness.
Mean Platelet Volume and Platelet Distributed Width Levels in Abo Blood Groups
(Wiley-blackwell, 2016) Celik, Hakim; Aslan, Mehmet; Kirmit, Adnan; Altiparmak, Ibrahim Halil; Kara, Erdal; Karakilcik, Ali Ziya
The Relationship Between Platelet Indices and Abo Blood Groups in Healthy Adults
(Wiley, 2019) Celik, Hakim; Duzenli, Ufuk; Aslan, Mehmet; Altiparmak, Ibrahim Halil; Kirmit, Adnan; Kara, Erdal; Karakilcik, Ali Ziya
Background ABO blood groups have been suggested to have a high correlation with cardiovascular diseases (CVDs). It has also been postulated that platelet indices, including mean platelet volume (MPV) and platelet distribution width (PDW), are very important in the development and progression of CVDs. However, despite these common associations with CVDs, as far as we know, there are no studies investigating platelet indices in ABO blood groups. Thus, the aim of this study was to investigate whether platelet indices are associated with ABO blood groups. Methods The study included 301 healthy volunteers (99 women and 202 men; mean age: 32.59 +/- 7.52 years) whose blood groups were determined by the gel column method using agglutination techniques. Platelet indices were studied by an automated blood counter. Results No considerable differences in age, gender, or Rh factors were observed among ABO blood groups. MPV was detected to be considerably lower in O and A blood group subjects than in AB and B blood group subjects. Similarly, PDW was significantly lower in O and A blood group subjects than in B blood group subjects. Additionally, MPV in the O blood group subjects was significantly lower than in the non-O blood group subjects. Conclusions Because MPV and PDW are used as markers of CVDs, individuals with O and A blood groups in this study may be considered to have a lower risk of CVDs than AB and B blood group subjects. However, prospective cohort studies involving a greater number of volunteers are needed to elucidate these relationships.