Browsing by Author "Asirci, Ismail"

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    Serum Ykl-40 Levels in Patients With Esophageal Squamous Cell Carcinoma
    (Libertas Acad, 2011) Yilmaz, Ozkan; Kemik, Ozgur; Kemik, Ahu; Sumer, Aziz; Dulger, A. Cumhur; Asirci, Ismail; Kotan, Cetin
    Aims and background: YKL-40 is a glycoprotein secreted by macrophages, neutrophils and malignant tumor cells. YKL-40 is expressed and secreted by several types of tumors. The aim of this study examined the clinical usefulness of YKL-40 for detection in esophageal squamous cell carcinoma (ESCC). Methods: Using ELISA kits, we measured the concentration of YKL-40 in serum from 100 patients with ESCC and compared this concentration with healthy population. Results: We found significantly higher serum levels of YKL-40 in patients with ESCC compared to the healthy population (P < 0.0001). Conclusions: These results suggested that regarding serum YKL-40 as a tumor marker could be benefical in the early clinical diagnosis.