Browsing by Author "Aslan, K."
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Article Enzyme Inhibition Properties of Calendula Officinalis, Matricaria Chamomilla, and Anthemis Pseudocotula: Kinetics and Molecular Docking Studies(ACG Publications, 2025) Aslan, K.; Kiziltas, H.; Guven, L.; Karagecili, H.; Arslan, D.; Gulcin, İ.This study determined the enzyme inhibition potential of three species (Calendula officinalis, Matricaria chamomilla, and Anthemis pseudocotula) from the Asteraceae family through in silico, followed by in vitro studies. Quinic acid, fumaric acid, gallic acid, chlorogenic acid, vanillic acid, quercetin, apigenin, and isorhamnetin were determined by LC-MS/MS in all of the species. Metabolic enzymes are essential catalysts regulating biochemical reactions within living organisms, facilitating energy production, detoxification, and biosynthesis. These enzymes play a crucial role in maintaining cellular homeostasis and are tightly regulated to ensure optimal metabolic function. High docking scores were also obtained for butyrylcholinesterase (BChE), α-glycosidase, α-amylase, and human carbonic anhydrase I and II enzymes (hCA I and hCA II). Among the extracts, Anthemis pseudocotula was concluded to be the best inhibitor for the enzymes, which was further determined by in vitro enzyme inhibition tests. Besides, it was concluded that all extracts showed anti-cholinergic, anti-diabetic, and anti-glaucoma properties. This is the first study determining the enzyme inhibition property of Anthemis pseudocotula and the three species' hCA I and hCA II inhibition activities. © 2025 ACG Publications. All rights reserved.Conference Object Microaggressions Towards People With Mental Illness(Cambridge Univ Press, 2024) Ayhan, C. H.; Sukut, O.; Bilgin, H.; Tanhan, F.; Aslan, K.Conference Object The Relationship Between Internal Stigmatisation, Recovery and Treatment Adherence in Individuals With Schizophrenia(Cambridge Univ Press, 2024) Keskiner, M. S.; Aktas, S.; Aktas, M. C.; Ayhan, H.; Aslan, K.Conference Object Variables Predicting Psychological Help Seeking Attitudes: Self-Stigma, Mental Health Literacy, and Depression/Anxiety(Cambridge Univ Press, 2024) Gundogdu, H.; Aslan, K.; Ayhan, H. C.; Aktas, C. M.
