Browsing by Author "Ayakta, H"

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Ca 125 Levels in Patients With Non-Hodgkin Lymphoma and Other Hematologic Malignancies
(Wiley, 2005) Dilek, I; Ayakta, H; Demir, C; Meral, C; Ozturk, M
Cancer antigen (CA 125) is a glycoprotein commonly used as a tumor marker. In this study, CA 125 levels were measured in 149 patients and 26 healthy control subjects. The study group included 69 non-Hodgkin lymphomas (NHL), 25 Hodgkin disease (HD), 20 acute myelocytic leukemia (AML), 14 chronic lymphocytic leukemia (CLL), 12 chronic myelocytic leukemia (CML), and nine multiple myeloma (MM) patients. CA 125 was elevated in 37 of the patients and in none of the control subjects. Average CA 125 level in NHL patients was significantly higher than the controls (56.2+/-9.2 U/ml, 7.99+/-1.05 U/ml respectively) (P<0.05). CA 125 levels were significantly higher in NHL patients with abdominal involvement (113.6+/-23.4 U/ml), with B-symptoms (72.3+/-13.2 U/ml), higher stage of the disease (stages III and IV -75.3+/-14.9 U/ml), bulky disease (99.9+/-30.4 U/ml) and in those with serosal involvement (103.1+/-18.5 U/ml) (P<0.05 for all). CA 125 levels were also elevated in seven patients with HD and in a patient with CLL with pleural effusion. In conclusion, for patients with NHL, high levels of CA 125 were associated with B-symptoms, advanced stage, bulky disease, abdominal, and serosal involvement. Therefore, CA 125 might be used as a marker to predict prognosis and to detect advanced disease in NHL.
Fibrosing Mediastinitis and Thrombosis of Superior Vena Cava Associated With Behcet's Disease
(Elsevier Sci Ireland Ltd, 2003) Harman, M; Sayarlioglu, M; Arslan, H; Ayakta, H; Harman, E
We present CT, MRI and venography findings in 13-year boy with mediastinal fibrosis and superior vena cava (SVC) thrombosis associated with Behcet's disease. Fibrosing mediastinitis is an excessive fibrotic reaction that occurs in the mediastinum and may lead to compression of mediastinal structures (especially vascular). This condition is usually idiopathic, though many (and perhaps most) cases in the USA are thought to be caused by an abnormal immunologic response to Histoplasma capsulatum infection. SVC syndrome secondary to extrinsic compression by mediastinal fibrosis combined with Behcet's disease has rarely been described. Radiological investigations of this syndrome are necessary to avoid a useless anticoagulant therapy. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.
Spontaneous Pregnancy in a Patient With Sheehan's Syndrome
(Elsevier Sci Ireland Ltd, 2003) Algün, E; Ayakta, H; Harman, M; Topal, C; Aksoy, H