Browsing by Author "Başaranoğlu, M."

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Assessment of Thyroid Nodules in Children: a Single Center Experience
(Yuzuncu Yil Universitesi Tip Fakultesi, 2020) Bitkin, E.Ç.; Karaman, S.; Başaranoğlu, M.
Thyroid nodules in children are less common than adults, but with a higher risk of malignancy, metastasis and recurrence. Therefore, detection, follow-up and treatment of thyroid nodules in children is very important. Our study retrospectively analyzed the demographic features, concomitant diseases and ultrasonography (USG) findings of thyroid nodules in children and aimed to obtain information about incidence of malignancy. We retrospectively analyzed the clinical, laboratory, thyroid USG, Fine needle aspiration biopsy (FNAB) and surgical results of 45 pediatric patients with thyroid nodules. Forty-five patients were included in the study, female domination was present, and most of the patients were adolescents. Six (13.3%) of the patients had a family history of thyroid cancer, and one had a history of radiation. Thyroid-related disease was present in 53.3% of the patients. Five patients had non-thyroid disease. Thyroid function tests were within normal limits in 33 (73.3%) of the patients. In our patients with pediatric thyroid nodules, FNAB was underwent in 46.6% according to the nodule size, and malignancy was detected in 2.2% of our patient group. Careful evaluation of thyroid nodules that are rarely seen in adults but higher in malignancy than adults should be evaluated. Diagnostic research for thyroid cancer is mostly done in adult patients, our study contributes to the assessment of risk conditions in thyroid nodules in children. © 2020, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Concurrent Acute Rheumatic Fever and Acute Poststreptococcal Glomerulonephritis: a Case Report
(Yuzuncu Yil Universitesi Tip Fakultesi, 2023) Çetin, M.; Gökçeoğlu, A.U.; Başaranoğlu, M.; Karaman, K.
Acute poststreptococcal glomerulonephritis and acute rheumatic fever are both postinfectious non-purulent sequelae of A group βhemolytic Streptococcus infections. In spite of prominent falls in the incidence, Acute Rheumatic Fever remains (ARF) an important cause of morbidity and mortality associated with acquired heart disease in underdeveloped territories. Acute poststreptococcal glomerulonephritis (APSGN) still remains a frequent form of glomerulonephritis in third-world countries, particularly in areas where the disease occurs in epidemics. Both diseases may be seen simultaneously in the same patient, but both diseases have different epidemiological, immunological and bacteriological features, however, this is a rare condition. We present a case of a 6.5 year old child with concurrent APSGN and ARF. © 2023, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Does Growth Hormone Therapy Enlarge Pituitary Adenomas
(Galenos Publishing House, 2022) Bitkin, E.Ç.; Kara, C.; Karaman, S.; Başaranoğlu, M.; Yokuş, A.; Tuncer, O.
Objective: Pituitary adenomas are detected incidentally in some cases of childhood growth hormone deficiency. Growth hormones may affect tumor growth. This study analyzed the reliability of growth hormone therapy in patients with non-functioning pituitary adenomas. Methods: The study group included 16 hypopituitary patients with incidentally detected non-functioning pituitary adenoma and treated with recombinant growth hormone. Age- and sex-matched 16 healthy children with incidental pituitary adenoma detected during investigation of chronic headache were selected as the control group. The data of the two groups were retrospectively reviewed and compared regarding the change in adenoma size over time. Results: Changes in adenoma size in the patient and control groups were -0.1 (-0.8-0.3) mm and -0.1 (-0.5-0.3) mm, respectively (p=0.664). Adenoma size growth was detected in 3 patients in the patient group and 5 patients in the control group (p=0.685). Conclusion: Our data suggest that recombinant growth hormone therapy does not produce pituitary adenomas, and thus its use is safe in growth hormone deficient children with incidentally detected non-functioning pituitary adenomas. © Copyright 2022 by Medical Journal of Bakırköy published by Galenos Yayınevi.
Evaluation of the Causes of Early and Late Thrombocytopenia in the Newborn
(OrtadogÂ u Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S., 2018) Karaman, K.; Demir, N.; Çetin, M.; Geylan, H.; Değer, İ.; Başaranoğlu, M.; Öner, A.F.
Objective: Thrombocytopenia is the most common hematological disorder that is encountered in the neonatal intensive care unit (NICU). The incidence of thrombocytopenia in neonates may varies greatly depending upon admitted patients population of unit. This study was performed on neonates admitted to Yuzuncu Yil University of Dursun Odabaş Medical Center of NICU, the incidence and causes of thrombocytopenia. Material and Methods: This retrospective study was conducted on the medical records of all neonates hospitalized at our hospital between May 2012 and March 2015 and those with thrombocytopenia were included in the study. The laboratory results of these newborns were retrospectively screened from the computer program and files, and included in the study were those with a thrombocytopenia level of less than 150.000/μL. Results: About 2780 patients were admitted to our neonatal intensive care unit during the study period. Of the 2780 neonates, 117 (4.2%) had thrombocytopenia (60.7% early onset and 39.3% late onset). Seventy-two of them (61.5%) were preterm. Intrauterine growth restriction, maternal hypertension, respiratory distress syndrome and sepsis were more common causes. Severe thrombocytopenia (<50.000/µL rate was found in 27% of neonates. In addition, although the rate of thrombocytopenia in asfixia was reported in the literature as 12-14%, this rate was 6.8% in our cases. There was no relation between occurrence of thrombocytopenia and gender. Conclusion: This study reveals that the causes of neonatal thrombocytopenia may show variations. In our study, intrauterine growth restriction, maternal hypertension, respiratory distress syndrome, and sepsis seem to be important risk factors for thrombocytopenia in neonates. Copyright © 2018 by Türkiye Klinikleri.
Evaluation of the Effect of Sound Intensity on Vital Signs in Neonatal Intensive Care Unit
(Yuzuncu Yil Universitesi Tip Fakultesi, 2020) Başaranoğlu, M.; Karaman, S.; Sönmez, B.; Tuncer, O.
Newborns, and especially prematures, suffer acute and chronic damage from noise during hospitalization. Therefore, it is important to monitor the noise levels of both the in-tub and out-of-tub environment. In this study we aimed to evaluate the effects of sound level measurement, noise sources and sound level on the vital signs of infants in Neonatal Intensive Care Unit. We measured the sound levels at three different time point and two different sites during the day to determine the sources of the noise using the Benetech Sound Level Meter GM1352. During each measurement, the number of people in two sections of the NICU, the number of devices working, and the vital signs of the patients were recorded. The average noise level in the first region was 58.58±10.7 dB and the average noise level in the second region was 50.17±6.407 db. There was a significant decrease in SaO2 values, especially during periods when the volume was high (p<0.01). It was also determined that the number of breaths, pulse and sleeplessness levels increased during periods when the sound level rose above a certain level. As a source of noise the number of people working devices used and the presence of the nurse desk in the section were found. İt was determined that the recommended sound level in our unit was generally exceeded and that these levels had various adverse effects on infants. It is necessary to take measures to reduce the negative effects of noise on babi es. © 2020, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
A Quadricuspid Aortic Valve That Was Misdiagnosed as Rheumatic Carditis: A 13-Year Case
(OrtadogÂ u Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S., 2021) Çetin, M.; Başaranoğlu, M.; Karaman, S.; Doğan, E.
Quadricuspid aortic valve anomaly is a very rare congenital heart anomaly. Its incidence is 0.01-0.04 percent. This anomaly is characterized by the presence of four aortic valves of the same or different sizes. This may often lead to progressive aortic regurgitation or rarely aortic valve stenosis. In aortic valve evaluation with transthoracic echocardiographic, if a careful examination is not performed, the diagnosis of quadricuspid aortic valve may be overlooked or may be misdiagnosed as insidious acute rheumatic carditis. Here, we presented a 13-year-old patient with quadricuspid aortic valve who was admitted to another center with chest pain, and was mistakenly diagnosed with insidious rheumatic carditis due to the aortic regurgitation detected on his transthoracic echocardiographic examination. We aimed to draw attention to this rare congenital heart valve disease. Copyright © 2021 by Türkiye Klinikleri.
Retrospective Evaluation of Our Patients With Lymphadenopathy
(Yuzuncu Yil Universitesi Tip Fakultesi, 2020) Karaman, S.; Uslu, E.; Başaranoğlu, M.; Kamaşak, T.; Bitkin, E.Ç.
Lymphadenopathy (LAP) is a common clinical finding in childhood. It is mostly reactive and has a good prognosis. Childhood cancers rarely occur. In our study, it was aimed to investigate the clinical and laboratory features of patients who were sent to the general child outpatient clinic due to LAP. The records of patients with LAP who applied to our General Children's outpatient clinics between January 2018 and December 2019 retrospectively. Age, gender, duration of complaint, treatment, systemic signs and symptoms, feat ures of lymph node, laboratory results was recorded The median age of 90 patients included in the study was 7 years; It takes place between 3-19 years. The complaints of the application were the most common neck swelling and submandibular and axillary sore after the second. Thirty (33%) of our cases had sore throat. Spleen and liver size were detected in 18 cases. In our study, 16% of cases were performed biopsy. Reactive hyperplasia in nine cases, nodular fasciitis in one case, granulomatous lymphadenitis in two cases, malignancy in two cases and Castleman Disease in one case were detected. We found that childhood lymphadenopathy frequently develops due to benign causes. © 2020, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.